New approach will help identify drugs that can "glue" proteins together
A new screening method that can test the effectiveness of therapeutic molecules designed to 'glue' proteins together in the body has been developed......»»
Study reveals how one enzyme hitches a ride on another to recognize tRNA
Imagine your body as a highly organized factory where workers tirelessly assemble proteins around the clock. These proteins are the machines and scaffolds that make up your body and are essential for various functions. In this factory, special delive.....»»
Boosting "natural killer" cell activity could improve cancer therapy
Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells—which kill infected, damaged, or malignant cells in the body—more effective against cancer. The approach, they say, could enable new treatment.....»»
Model shows how plankton survive in a turbulent world
How do particles move in turbulent fluids? The answer to this question can be found in a new model presented in a thesis from the University of Gothenburg. The model could help speed up the development of new drugs......»»
New fluorescent reporting system illuminates accumulation of unfolded proteins in endoplasmic reticulum
The endoplasmic reticulum (ER) is a major organelle responsible for protein folding and trafficking. Protein folding stress in the ER can lead to the accumulation of unfolded or misfolded proteins, known as ER stress, which activates the unfolded pro.....»»
Researchers identify potential hazards in biosolid fertilizers
Fertilizers manufactured from the sludgy leftovers of wastewater treatment processes can contain traces of potentially hazardous organic chemicals, according to a new study by Johns Hopkins University researchers......»»
Scientists identify safe havens we must preserve to prevent "the sixth great extinction of life on Earth"
In a new article, a coalition of conservationists and researchers have shown how we can protect Earth's remaining biodiversity by conserving just a tiny percentage of the planet's surface. This affordable, achievable plan would make it possible for u.....»»
AI-based approach matches protein interaction partners
Proteins are the building blocks of life, involved in virtually every biological process. Understanding how proteins interact with each other is crucial for deciphering the complexities of cellular functions, and has significant implications for drug.....»»
Apple Intelligence goes against the entire Apple ethos — in a good way
Apple's walled garden is getting upended by its more open approach to AI partnerships......»»
Non-coding RNA acts as "superhighway" for gene expression, study finds
The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins—yet it exists in large quantities......»»
Security Bite: Meta will start using your data to train its AI next week, but you may be able to opt out
9to5Mac Security Bite is exclusively brought to you by Mosyle, the only Apple Unified Platform. Making Apple devices work-ready and enterprise-safe is all we do. Our unique integrated approach to management and security combines state-of-the-art App.....»»
New computational tool helps interpret AI models in genomics
Artificial intelligence continues to squirm its way into many aspects of our lives. But what about biology, the study of life itself? AI can sift through hundreds of thousands of genome data points to identify potential new therapeutic targets. While.....»»
Radioactive drugs strike cancer with precision
Tumor-seeking radiopharmaceuticals promise targeted treatments with fewer side effects. Enlarge / Pharma interest and investment in radiotherapy drugs is heating up. (credit: Knowable Magazine) On a Wednesday morning in.....»»
An efficient protein delivery system with spider minor ampullate silk protein nanoparticles
In a study published in the journal MedComm, researchers have developed an efficient protein delivery carrier based on spider silk proteins (spidroins), derived from Araneus ventricosus minor ampullate silk protein (MiSp). The MiSp-based nanoparticle.....»»
New insights into how cell shape influences protein transport rates
When a cell spreads out or changes its shape to adapt to its environment, the transport rate of proteins between the nucleus and cytoplasm changes. Previously, scientists assumed this change was caused by a shift in the size of the nuclear envelope's.....»»
A simple, fast, and versatile method for selective bromination of indole alkaloids
The development of drugs through chemical modifications of naturally occurring indole alkaloids has emerged as an attractive research area. However, due to their reactivity, the selective functionalization at the C5 position of the indole ring has be.....»»
Community-led disaster resilience model benefiting those that need it most
A new report from Monash University's Fire to Flourish program has identified how a community-led approach to disaster resilience is delivering positive impacts for affected communities......»»
Concentric AI’s compliance feature helps organizations identify and address compliance risks
Concentric AI announced it has incorporated new industry compliance capabilities into its Semantic Intelligence DSPM solution. With these new innovative features, Concentric AI now identifies data risk within organizations’ environments applicable.....»»
Study reveals molecular mechanisms of somatostatin receptor 5 activation by neuropeptides and drugs
Somatostatin receptors (SSTRs) constitute a crucial family of G protein-coupled receptors (GPCRs) that play pivotal roles in regulating hormone secretion and inhibiting tumor growth......»»
Old drugs new tricks—novel approach shows "enormous potential" for rapid antibiotic discovery
An innovative project to re-purpose existing drugs for their potential as antibiotics has uncovered a highly promising candidate with a potent and unique way of killing drug resistant bacteria......»»
Boosting the synthesis of stable sugar compounds with a novel nature-inspired approach
Researchers from the National University of Singapore (NUS) have developed a new biomimetic concept to convert naturally occurring sugars into diverse classes of stable glycosides and glycoproteins without using protecting-group chemistry. This innov.....»»