New and improved drug-delivery molecules for skeletal muscle
Researchers from Tokyo Metropolitan University have created a new drug-delivery molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RN.....»»
More bad news for psychedelic drug company: FDA expands probe after rejection
Psychedelic drug company Lykos already slashed staff and overhauled leadership. Enlarge / President of Multidisciplinary Association for Psychedelic Studies (MAPS) Rick Doblin speaks onstage during the 2023 Concordia Annual Sum.....»»
Closing the RNA loop holds promise for more stable, effective RNA therapies
New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego. The advance holds promise for a range of diseases, offering a more enduri.....»»
Telegram CEO Pavel Durov awaits charges in France as firm denies law-breaking
Telegram accused of not cooperating on drug trafficking and child sexual content. Enlarge / Pavel Durov, CEO and co-founder of Telegram, speaks at TechCrunch Disrupt SF 2015 on September 21, 2015, in San Francisco, California. (c.....»»
Controlling molecular electronics with rigid, ladder-like molecules
As electronic devices continue to get smaller and smaller, physical size limitations are beginning to disrupt the trend of doubling transistor density on silicon-based microchips approximately every two years, according to Moore's law. Molecular elec.....»»
For metro governments, bigger may not be economically better
When big cities gobble up smaller ones nearby, residents often are told a consolidated government is more efficient, providing improved services and other economic benefits......»»
The promise of synthetic cells
For over a decade, scientists have made extraordinary progress on the long-held dream of fabricating an entire cell from nonliving molecules and materials......»»
Judge upholds $350,000 award against Michigan dealership for wrongful repossession
A federal judge upheld a $350,000 punitive damages award against a Michigan dealership in a spot delivery and wrongful repossession case......»»
Test of a prototype quantum internet runs under New York City for half a month
To introduce quantum networks into the marketplace, engineers must overcome the fragility of entangled states in a fiber cable and ensure the efficiency of signal delivery. Now, scientists at Qunnect Inc. in Brooklyn, New York, have taken a large ste.....»»
Extreme rainfall event study demonstrates improved forecasting via physics-guided machine learning
A research team focused on the extreme rainfall event of "21·7" in Henan in 2021. By analyzing anomalous physical characteristics and understanding multi-model forecast biases, they significantly enhanced the accuracy of precipitation intensity fore.....»»
Ultra-sensitive photothermal microscopy technique detects single nanoparticles as small as 5 nm
The detection of individual particles and molecules has opened new horizons in analytical chemistry, cellular imaging, nanomaterials, and biomedical diagnostics. Traditional single-molecule detection methods rely heavily on fluorescence techniques, w.....»»
Labor board confirms Amazon drivers are employees, in finding hailed by union
“We are Amazon workers”: Delivery drivers celebrate labor board finding. Enlarge (credit: Jaroslaw Kilian | iStock Editorial / Getty Images Plus) Amazon may be forced to meet some unionized delivery drivers at the ba.....»»
New "chiral vortex" of light allows chemists to "see" molecules through the mirror
An entirely new structure of light is helping to measure chirality in molecules more accurately and robustly than ever before, in a major potential step for the pharmaceutical industry......»»
Researchers synthesize molecular aggregates for solar energy applications
No molecule stands alone—they need others, at least when it comes to being able to display useful photophysical, electronic, and chemical properties. When individual molecules combine into an aggregate, or a complex of two or more molecules, they b.....»»
Chemists succeed in upscaling a common reagent for industrial level applications
The metallic element samarium, when bound with other elements, is an incredibly useful chemical reagent for synthesizing molecules that can lead to new pharmaceuticals. Discovered in a Russian mine in 1879, the element was named after the mineral it.....»»
FDA green-lights fall COVID-19 boosters
Updated mRNA vaccines from Pfizer and Moderna are ready to roll. Enlarge (credit: Getty Images) As the COVID-19 case count continues to tick upward, the US Food and Drug Administration has approved an updated vaccine for.....»»
Engineers design lookalike drug nanocarrier to evade lung"s lines of defense
A drug-carrying molecule designed to cure disease by slipping past the lung's natural defenses offers new hope for people with chronic or deadly respiratory diseases, say its creators, researchers in assistant professor Liheng Cai's Soft Biomatter La.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
AI tackles one of the most difficult challenges in quantum chemistry
New research using neural networks, a form of brain-inspired AI, proposes a solution to the tough challenge of modeling the states of molecules......»»
Improving the accuracy of global cropland mapping
To address the needs of the agricultural monitoring community, IIASA scientists fused two of the latest high-quality, high-resolution, remotely sensed cropland products to produce an improved cropland map for early warning and food security assessmen.....»»
Novel silica nonwoven fabric scaffold enhances understanding of cell-to-cell interactions
Communication and coordination among different cells are fundamental aspects that regulate many functions in our body. This process, known as paracrine signaling, involves the release of signaling molecules by a cell into its extracellular matrix (EC.....»»