Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases
A recent study from the lab of Tanya Kalin, MD, Ph.D., professor of Child Health and Internal Medicine at the University of Arizona College of Medicine—Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung ca.....»»
Transparent worms with glowing proteins may help fertility treatments
The development of maternal egg cells is pivotal for survival—but also precarious. During meiosis, the DNA-containing chromosomes can easily be broken or lost, causing infertility, miscarriage or genetic disorders like Down syndrome. Scientists hav.....»»
Spatial interactomics tool maps protein interactions to fight lung cancer
As Ahmet F. Coskun and his team of researchers continue their mission to create a 3D atlas of the human body, mapping cells and tissues, they're making discoveries that could lead to better treatments for the most common type of lung cancer......»»
DNA repair by cooperation between proteins: A look inside the cell"s repair hub
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells......»»
Sugar-like nanoparticle covering could boost cancer drug delivery
A spoonful of sugar might actually help medicine go down, according to recent research from the University of Mississippi. And it could reduce the harmful side effects of cancer treatment. Instead of a literal spoonful of sugar, however, the research.....»»
Study reveals how caregiving for loved ones shapes lives of Cleveland"s chronically homeless
Shortly after Jerome's mother died of cancer, he experienced what he described as a "mental breakdown" and, before too long, found himself without a home. Taking care of his mother had drained him—both emotionally and financially......»»
Researchers discover the essential role of light in the organization of retinal cells
New work from the laboratory of Michel Cayouette, Director of the Cellular Neurobiology Research Unit at the Montreal Clinical Research Institute (IRCM) and Professor in the Faculty of Medicine at the Université de Montréal, reveals for the first t.....»»
Human Cell Atlas achieves leap in the understanding of the human body
Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the publication on 20 November of a collection of more than.....»»
Nanofibers made of copper-binding peptides disrupt cancer cells
While toxic in high concentrations, copper is essential to life as a trace element. Many tumors require significantly more copper than healthy cells for growth—a possible new point of attack for cancer treatment......»»
Can going to a haunted house boost the immune system?
Study found marked decrease in inflammatory markers and white blood cells after visiting a haunted house. Spooky season has come and gone, but those Halloween revelers who took in.....»»
By exerting "crowd control" over mouse cells, scientists make progress towards engineering tissues
Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs. In a paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist Matt Thomson characteriz.....»»
Porch pirates appear to be accessing AT&T data to track iPhone deliveries
A new report today suggests that porch pirates – thieves who steal packages left on doorsteps shortly after delivery – have accessed tracking data from AT&T systems to follow iPhone deliveries. There has been a marked uptick in iPhones being s.....»»
Human brain organelles study shows dopamine neurons must work a lot harder than those in primate relatives
A team of neurologists, bioengineers and radiologists has found that two neurons in the human brain that code for dopamine production have to work harder than similar cells in primate relatives. The group has posted a paper describing their work on t.....»»
Viscosity of materials key to cell differentiation: New insights could improve design of biomaterials
An IBEC-led study has revealed how mesenchymal stem cells respond to the viscosity of their environment, a key aspect in their differentiation process......»»
How marine worms regenerate lost body parts: Return of cells to stem cell-like state could be key
Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others are not is not fully understood. Molecular biologists Alexander Stockinger, Leonie Adelmann and Florian Raible from the Max Per.....»»
Selenoproteins open new strategies for treating certain cancers in children
Selenoproteins are crucial for several biological functions, including the breakdown of harmful substances, immune system support, and regulating metabolic processes. However, in specific contexts, these proteins can be misused and shield cancer cell.....»»
Genes of ancient animal relatives used to grow a mouse: Study reveals hidden history of stem cells
An international team of researchers has achieved an unprecedented milestone: the creation of mouse stem cells capable of generating a fully developed mouse using genetic tools from a unicellular organism, with which we share a common ancestor that p.....»»
Study uncovers role of tissue viscoelasticity in cell response
To the casual eye, a memory foam mattress would appear to have no relationship to the behavior of cells and tissues. But an innovative study carried out at the Centro de Investigaciones Cardiovasculares (CNIC) in Madrid shows that viscoelasticity—t.....»»
Telescope for NASA"s Roman mission complete, delivered to Goddard
NASA's Nancy Grace Roman Space Telescope is one giant step closer to unlocking the mysteries of the universe. The mission has now received its final major delivery: the Optical Telescope Assembly, which includes a 7.9-foot (2.4-meter) primary mirror,.....»»
Using genetic code expansion to study membrane proteins
Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it possible to modify proteins directly in living cells to giv.....»»
Scientists engineer stable protein complexes for targeted cancer therapies
Researchers from Auburn University, partnering with the University of Basel in Switzerland, have discovered a new way to make a cancer-targeting protein complex more stable, opening doors to better cancer treatments. Led by Dr. Rafael Bernardi from A.....»»