Must mRNA be cloaked in a lipid coat to serve as a vaccine?
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»
Scientists are testing mRNA vaccines to protect cows and people against bird flu
The bird flu outbreak in U.S. dairy cows is prompting development of new, next-generation mRNA vaccines—akin to COVID-19 shots—that are being tested in both animals and people......»»
Misleading COVID-19 headlines from mainstream sources did more harm on Facebook than fake news, study finds
Since the rollout of the COVID-19 vaccine in 2021, fake news on social media has been widely blamed for low vaccine uptake in the United States—but research by MIT Sloan School of Management Ph.D. candidate Jennifer Allen and Professor David Rand f.....»»
As bird flu spreads in cows, US close to funding Moderna’s mRNA H5 vaccine
If trials are successful, US government likely to buy doses for vaccine stockpile. Enlarge (credit: Digicom Photo/Science Photo Library via Getty) The US government is nearing an agreement to bankroll a late-stage trial.....»»
New approach uses "cloaked" proteins to deliver cancer-killing therapeutics into cells
An interdisciplinary collaboration has designed a way to "cloak" proteins so that they can be captured by lipid nanoparticles, which are akin to tiny bubbles of fat. These bubbles are small enough to sneak their hidden cargo into living cells, where.....»»
Unveiling a novel AAK1 inhibitor: How chemical proteomics unlock therapeutic potential
Enhancing drug development for life-threatening diseases like cancer hinges on a deep understanding of protein kinases, making it a focal point for researchers. These enzymes, encoded by more than 500 human genes, serve as critical players in cellula.....»»
Genetic mutation responsible for new coat pattern in cats in Finland identified
A team of geneticists and animal welfare specialists from the U.K. and one from the U.S. has identified the genetic mutation responsible for a newly discovered cat coat color pattern in Finland. In their study, published in the journal Animal Genetic.....»»
Lipid nanoparticle-mRNA regimen reverses inflammation and aids recovery from diabetic wounds in mice
Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown t.....»»
There’s New Hope for an HIV Vaccine
A trial vaccine has succeeded in generating low levels of antibodies needed to target HIV. It’s a first but much-needed step toward preventing infection......»»
Keurig’s single-serve coffee maker just got a bold discount
The Keurig K-Select coffee maker, which can brew cups of coffee at different sizes from K-Cup pods, is on sale from Best Buy for $120 following a $30 discount......»»
Protein assembly research shows molecular roll of the dice delivers winning combinations
Australian researchers have shed light on the shape-shifting capabilities of protein assemblies, with results that could revolutionize fields from biomanufacturing to vaccine development......»»
Genes spatially organize for efficient mRNA splicing, study shows
The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 times smaller than the width of a human hair, genes a.....»»
MATE transporter facilitates bitter saponin transport from cytoplasm to vacuole
Domestic soybeans serve as an important source of healthy edible plant oil and high-quality plant protein in our food culture. In addition to the well-known components of oil (approximately 20%), protein (approximately 40%), and carbohydrates (approx.....»»
An adjuvant made in yeast could lower vaccine cost and boost availability
Vaccines save lives, as proven during the recent pandemic, but one component of most vaccines—including the Novavax COVID-19 vaccine—goes unheralded: a molecule or other compound that primes the immune system to mount a more robust defense agains.....»»
What can early Earth teach us about the search for life?
Earth is the only life-supporting planet we know of, so it's tempting to use it as a standard in the search for life elsewhere. But the modern Earth can't serve as a basis for evaluating exoplanets and their potential to support life. Earth's atmosph.....»»
Decoding development: mRNA"s role in embryo formation
A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights into how pluripotent cells a.....»»
FortiGate 200G series boosts campus connectivity for Wi-Fi 7
Fortinet announced a new next-generation firewall (NGFW) appliance with the security and networking performance needed to serve as the backbone of the modern campus. Built on the Fortinet operating system, FortiOS, and the latest, fifth-generation Fo.....»»
Developing a tech platform for fast, robust series production of nanoparticles
Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are neede.....»»
Researchers turn to two crops to tackle environmental harm of apparel made with synthetic fibers
From risottos to sauces, mushrooms have long been a staple in the kitchen. Now fungi are showing the potential to serve up more than just flavor—as a sustainable, bendy material for the fashion industry......»»
How to upload a custom coat of arms in Manor Lords
The banner you fly in Manor Lords should represent yourself as closely as possible. If the options provided don't do the trick, here's how to add your own......»»
Ubiquiti releases new Dream Machine Pro Max to serve large deployments with thousands of devices
When released a few years ago, the Dream Machine Pro became a popular device for small and medium-sized businesses. I’ve deployed and managed a handful of them in various environments and found them to be a great device. It’s a really easy and af.....»»