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Most "silent" genetic mutations are harmful, not neutral, a finding with broad implications

In the early 1960s, University of Michigan alumnus Marshall Nirenberg and a few other scientists deciphered the genetic code of life, determining the rules by which information in DNA molecules is translated into proteins, the working parts of living.....»»

Category: topSource:  physorgJun 8th, 2022

Scientists discover chemical probes for previously "undruggable" cancer target

Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»

Category: topSource:  informationweekRelated NewsOct 15th, 2024

How profits from big pharma"s use of genetic information could revolutionize nature conservation

The blue blood of threatened horseshoe crabs contains a chemical essential for testing the safety of vaccines. So these ancient creatures are highly sought after by pharmaceutical companies worldwide, contributing to declines in their populations......»»

Category: topSource:  informationweekRelated NewsOct 15th, 2024

Bacteria discovered in healthy vertebrate brains point to a potential role in brain function

Researchers at the University of New Mexico have identified the presence of bacteria in the healthy brains of fish. Understanding this connection between bacteria and animal brains could have future implications for the study of Alzheimer's disease......»»

Category: topSource:  physorgRelated NewsOct 15th, 2024

How "vaccinating" plants could reduce pesticide use and secure global food supplies

In a growing and changing world, we need to find ways of putting food on everyone's table. Pesticides have enabled mass cultivation on an incredible scale, but they can have harmful secondary effects on humans and wildlife, and pests are rapidly evol.....»»

Category: topSource:  physorgRelated NewsOct 15th, 2024

Astronomers detect very-high-energy gamma-ray emission surrounding distant pulsar

Using the Large High-Altitude Air Shower Observatory (LHAASO), an international team of astronomers have detected very-high-energy (VHE) gamma-rays around the pulsar PSR J0248+6021, which may be the pulsar's halo or a pulsar wind nebula. The finding.....»»

Category: topSource:  physorgRelated NewsOct 15th, 2024

Report: Climate emergencies threaten our collective security, but governments are flying blind into the storm

You probably missed it, but a few months ago a report was published that inspected how the UK government prepared for major emergencies. What it found has profound implications for the whole country......»»

Category: topSource:  physorgRelated NewsOct 14th, 2024

China"s child policies will increase its future carbon emissions, researchers say

Relaxing its restrictions on family size would make it more difficult for China to achieve its goal to be carbon neutral by 2060, according to a new study by UCL researchers......»»

Category: topSource:  physorgRelated NewsOct 14th, 2024

Adaptability of trees persists after millions of years of climate change, finds study

Seven of the most common forest trees in Europe have been shown to be able to shelter their genetic diversity from major shifts in environmental conditions. This is despite their ranges having shrunk and the number of trees having fallen sharply duri.....»»

Category: topSource:  physorgRelated NewsOct 14th, 2024

Scientists develop a new method to study gene function in cells and tissue

The Gaublomme lab has developed a new optical pooled screening approach called CRISPRmap, which enables the coupling of optical properties of single cells to targeted genetic perturbations. Optical phenotypes are typically inaccessible for sequencing.....»»

Category: topSource:  pcmagRelated NewsOct 14th, 2024

Is life possible on a Jupiter moon? NASA goes to investigate

Is there anywhere else in our solar system that could support life? An imposing NASA probe is due to lift off on Monday on a five-and-a-half-year journey to Europa, one of Jupiter's many moons, to take the first detailed step toward finding out......»»

Category: topSource:  theglobeandmailRelated NewsOct 14th, 2024

The PS Vita’s forgotten Silent Hill game deserves a revival

With Silent Hill 2's excellent remake out now, the more obscure parts of Konami's series deserve to make a comeback too......»»

Category: topSource:  digitaltrendsRelated NewsOct 13th, 2024

Europa Clipper mission to investigate potential habitability of Jupiter"s moon

A NASA spacecraft is ready to set sail for Jupiter and its moon Europa, one of the best bets for finding life beyond Earth......»»

Category: topSource:  physorgRelated NewsOct 12th, 2024

GM touts broad profitability to build investor confidence amid EV shift

CFO Paul Jacobson said GM expects flat financial results in 2025 even if pricing declines and that the automaker's outlook should inspire confidence about its earnings potential......»»

Category: topSource:  autonewsRelated NewsOct 11th, 2024

Stellantis confirms CEO Carlos Tavares to retire in 2026 amid broad management shake-up

The confirmation comes weeks after Stellantis said it was searching for his successor, though at the time it said it was possible he could remain after his contract expires......»»

Category: topSource:  autonewsRelated NewsOct 11th, 2024

AI decodes microbes" message in milk safety testing approach

By combining the genetic sequencing and analysis of the microbes in a milk sample with artificial intelligence (AI), researchers were able to detect anomalies in milk production, such as contamination or unauthorized additives. The new approach could.....»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Up in smoke: DIY tech to combat wildfires

As wildfires become a more frequent and dangerous part of life, especially in the Pacific Northwest, finding solutions that everyone can use is more important than ever. By June 2024, the Pacific Northwest had already seen more trees burn than in all.....»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Magnetoelectric nanodiscs offer remote brain stimulation without implants or genetic modification

Novel magnetic nanodiscs could provide a much less invasive way of stimulating parts of the brain, paving the way for stimulation therapies without implants or genetic modification, MIT researchers report......»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Advanced model predicts gene architecture via nucleosome position

DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner that allows it to function efficiently. Nucleosomes facilitate DNA compaction and also play a crucial role in regulating ge.....»»

Category: topSource:  informationweekRelated NewsOct 10th, 2024

Genetic tweaks show potential for making oats more nutritious and increasing shelf life

A recent study from McGill University proposes a way to enhance the nutritional value of oats by increasing their content of oleic acid, a type of healthy fat known for its cardiovascular heart benefits and potential to lower diabetes......»»

Category: topSource:  theglobeandmailRelated NewsOct 10th, 2024

Yes, nature is complex—but saving our precious environment means finding ways to measure it

Nature loss directly threatens half the global economy. The rapid destruction of biodiversity should alarm the many Australian businesses dependent on nature, such as those in agriculture, tourism, construction and food manufacturing. Yet nature cons.....»»

Category: topSource:  physorgRelated NewsOct 10th, 2024