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Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein

Recent failed clinical trials of a drug designed to clear the mutant Huntingtin protein that causes Huntington's disease (HD) heightens the need for new approaches for the devastating, incurable, progressive neurodegenerative genetic disorder. Scient.....»»

Category: biomedSource:  sciencedailyJun 3rd, 2021

A toxic chemical was blamed for killing thousands of Teesside crabs, but a study explains why pyridine isn"t the culprit

In October 2021, thousands of dead and dying crabs and lobsters washed up along 45 miles (70km) of coastline in north-east England. This mass-mortality event coincided with the redevelopment of one of the UK's largest ports at Teesside......»»

Category: topSource:  physorgRelated NewsSep 17th, 2024

An unexpected protein connection in maize growth and defense could enhance crop resilience

Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored......»»

Category: topSource:  marketingvoxRelated NewsSep 17th, 2024

Team discovers naturally occurring DNA-protein hybrids

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»

Category: topSource:  marketingvoxRelated NewsSep 17th, 2024

8-year-old girl drove mom"s SUV on Target run: "We did let her finish her Frappuccino"

8-year-old girl drove mom"s SUV on Target run: "We did let her finish her Frappuccino".....»»

Category: topSource:  theglobeandmailRelated NewsSep 16th, 2024

Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane

For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»

Category: topSource:  physorgRelated NewsSep 16th, 2024

The Jackery Explorer 300 Plus portable power station is $240 today normally $300

Target is offering the Jackery Explorer 300 Plus portable power station at a fantastic discount today. Here's why you should care, and shop it......»»

Category: topSource:  marketingvoxRelated NewsSep 16th, 2024

Target dropped the price of this Lenovo ThinkPad from $875 to $500

The Lenovo ThinkPad L13 Yoga Gen 2 is on sale at Target. Save $375 when you purchase in-store or online, but act fast!.....»»

Category: topSource:  digitaltrendsRelated NewsSep 15th, 2024

Hurry! Target is having a mini sale on Beats headphones this weekend

Target is having a huge sale on Beats headphones! Save big on four exciting models while these discounts are still in effect. But act fast!.....»»

Category: topSource:  digitaltrendsRelated NewsSep 14th, 2024

This 17-inch gaming laptop deal from Acer cuts $200 off the Nitro

Experience PC gaming on-the-go with the awesome Acer Nitro 17.3-inch Gaming Laptop, now on sale at Target for a limited time only!.....»»

Category: topSource:  digitaltrendsRelated NewsSep 14th, 2024

Study shows microbial diversity differences in volcanic cones and craters

Volcanic activity alters the Earth's surface and promotes the development of new ecosystems, providing valuable models for studying soil formation processes such as microbial composition and vegetation succession. Increasing evidence suggests that so.....»»

Category: topSource:  physorgRelated NewsSep 13th, 2024

Edible insects show promise as sustainable nutritional source

As the global population grows and traditional livestock production increasingly strains environmental resources, there is a rising interest in alternative protein sources. Edible insects, particularly grasshoppers, are abundant in regions like Camer.....»»

Category: topSource:  physorgRelated NewsSep 13th, 2024

Target dropped the price of this 55-inch TV to under $300 today

The 55-inch TCL S5 Series 4K TV is already pretty affordable, but it's even cheaper from Target after a $70 discount brings its price down to only $280 today......»»

Category: topSource:  digitaltrendsRelated NewsSep 13th, 2024

Hurry! The 9th Gen iPad has a big price cut at Target

The 9th Gen iPad is getting a solid markdown at Target today! For a limited time, you’ll be able to buy it for only $230!.....»»

Category: topSource:  digitaltrendsRelated NewsSep 12th, 2024

Target is selling the Samsung Tab A7 for just $100 today

Are you looking for a new tablet on the cheap? For a limited time, Target is selling the Samsung Galaxy Tab A7 Lite for only $100!.....»»

Category: topSource:  digitaltrendsRelated NewsSep 12th, 2024

Chinese hackers target Windows servers with SEO poisoning campaign

So far, a couple dozen websites, scattered mostly throughout Asia, were compromised......»»

Category: topSource:  marketingvoxRelated NewsSep 12th, 2024

A CGE model for provincial analysis of China"s carbon neutrality target

Computable General Equilibrium (CGE) models have become increasingly prevalent, offering valuable insights into the complex and interconnected economic and environmental impacts of climate mitigation strategies. The China Regional Energy Model (C-REM.....»»

Category: topSource:  physorgRelated NewsSep 11th, 2024

Canon’s smallest EOS R camera just got a $200 discount

The The Canon EOS R100, a mirrorless camera that's perfect for beginners, is available for an affordable price of $400 from Target following a $200 discount......»»

Category: topSource:  digitaltrendsRelated NewsSep 11th, 2024

Target slashed the prices of Ninja air fryers this week

The Ninja Foodi Digital Air Fry Oven and the Ninja Foodi XL Pro Air Fry Oven are both on sale from Target at $70 off, but we're not sure for how much longer......»»

Category: topSource:  digitaltrendsRelated NewsSep 11th, 2024

This Cuisinart air fryer is usually $230, but it’s on sale for $100

The Cuisinart Air Fryer Toaster Oven, a full-size toaster oven with a built-in air fryer, is on sale from Target for an affordable $100 after a $130 discount......»»

Category: topSource:  digitaltrendsRelated NewsSep 11th, 2024

Illuminate your game room, or any room, with the Govee Glide RGBIC kit — 50% off

This Govee Glide RGBIC lighting kit is the perfect way to illuminate any room in your house. They're 50% off today at Target......»»

Category: topSource:  digitaltrendsRelated NewsSep 11th, 2024