Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein
Recent failed clinical trials of a drug designed to clear the mutant Huntingtin protein that causes Huntington's disease (HD) heightens the need for new approaches for the devastating, incurable, progressive neurodegenerative genetic disorder. Scient.....»»
The internet can be toxic—but there are also online oases where mutual care flourishes
The internet can be a toxic place. Disinformation, hate speech and trolling are not just abundant—they are encouraged by the economy of clicks which governs many online platforms. There are no good clicks, no bad clicks, only clicks. By that metric.....»»
Increasing protein in staple crops could help alleviate global protein shortage
A Mississippi State biologist's research in improving global nutrition and sustainability is featured this week in New Phytologist......»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
Proof-of-concept study uses X-rays to target mock-up asteroids in a vacuum
An X-ray pulse may be able to vaporize the surface of an asteroid and change its trajectory, according to a proof-of-concept paper published in Nature Physics. A laboratory experiment that mimics the deflection of an asteroid model using this techniq.....»»
Elon Musk shares new target date for Starship voyage to Mars
But it's worth noting that the SpaceX CEO's forecasts often slip......»»
New biosensor illuminates physiological signals in living animals
Eric Schreiter and Luke Lavis thought they had figured it out. In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?
Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?.....»»
How much auto demand will the Fed"s half-point rate cut produce?
The Federal Reserve cut its benchmark rate target 0.5 percentage points on Sept. 18, which could reduce the market interest rates that Cox Automotive polling indicates are dealerships' No. 1 challenge......»»
Copper-based nanocapsules shown to enhance radiotherapy effectiveness
In a study published in Nature Nanotechnology, researchers discovered that cuproptosis may serve as a new target for radiosensitization in re-irradiation......»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
This Whirlpool mini fridge is only $110 today at Target — normally it’s $150
Want a place to store cold drinks and snacks? This Whirlpool mini fridge deal at Target is just what you need to shop. Check it out......»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
8-year-old who drove to an Ohio Target in mom"s SUV caught on dashcam video: Watch
8-year-old who drove to an Ohio Target in mom"s SUV caught on dashcam video: Watch.....»»
Half-point Fed rate cut could spur consumer demand at auto dealerships
Car dealerships might see higher demand from consumers following the Federal Reserve's decision Sept. 18 to cut its benchmark rate target 0.5 points, according to Edmunds......»»
Southern California suspects burglarize Target, hide stolen goods in baby stroller
Southern California suspects burglarize Target, hide stolen goods in baby stroller.....»»
Don’t want a PS5 Pro? Grab the PS5 Slim 1TB manufacturer refurbished for $425
Don't want the new $700 PS5 Pro? No problem. Why not consider this refurbished PS5 Slim 1TB for a discount at Target......»»
A toxic chemical was blamed for killing thousands of Teesside crabs, but a study explains why pyridine isn"t the culprit
In October 2021, thousands of dead and dying crabs and lobsters washed up along 45 miles (70km) of coastline in north-east England. This mass-mortality event coincided with the redevelopment of one of the UK's largest ports at Teesside......»»
An unexpected protein connection in maize growth and defense could enhance crop resilience
Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored......»»
Team discovers naturally occurring DNA-protein hybrids
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»