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Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein

Recent failed clinical trials of a drug designed to clear the mutant Huntingtin protein that causes Huntington's disease (HD) heightens the need for new approaches for the devastating, incurable, progressive neurodegenerative genetic disorder. Scient.....»»

Category: biomedSource:  sciencedailyJun 3rd, 2021

Illuminate your game room, or any room, with the Govee Glide RGBIC kit — 50% off

This Govee Glide RGBIC lighting kit is the perfect way to illuminate any room in your house. They're 50% off today at Target......»»

Category: topSource:  digitaltrendsRelated NewsSep 11th, 2024

“HAIL HOLY TERROR”: Two US citizens charged for running online “Terrorgram Collective”

White accelerationist terror meets social media. The US government recently announced multiple charges against the alleged leaders of the "Terrorgram Collective," which does just what it sounds like—it promotes terrorism on the Tel.....»»

Category: topSource:  arstechnicaRelated NewsSep 11th, 2024

Target is selling Lenovo Chromebooks for $100, with a catch

If you're hunting for a very budget-oriented laptop that won't break the bank, this Lenovo laptop is worth grabbing, even with the catch......»»

Category: topSource:  digitaltrendsRelated NewsSep 10th, 2024

Target slashed the price of this CLX gaming PC with RTX 4080

The CLX Horus gaming PC is stacked with high-end hardware including the latest 4080 graphics card, masses of storage, and 64GB RAM. It's on sale now at Target......»»

Category: topSource:  digitaltrendsRelated NewsSep 10th, 2024

Lucid teases midsize model for 2026; says Gravity EV will use Tesla"s NACS plug next year

Lucid's three-row Gravity crossover will use Tesla's NACS plug next year while its lower-cost midsize model will target the Tesla Model Y in 2026, CEO Peter Rawlinson tells Automotive News......»»

Category: topSource:  autonewsRelated NewsSep 10th, 2024

Lucid teases "midsize" model for 2026; says Gravity EV will use Tesla"s NACS plug next year

Lucid's three-row Gravity crossover will use Tesla's NACS plug next year while its lower-cost 'midsize' model will target the Tesla Model Y in 2026, CEO Peter Rawlinson tells Automotive News......»»

Category: topSource:  autonewsRelated NewsSep 10th, 2024

BYD sets higher annual sales target, brokerage report shows

The goal would put BYD almost at par with Ford, which ranked sixth by global sales in 2023 with 4.4 million vehicles sold......»»

Category: topSource:  autonewsRelated NewsSep 10th, 2024

Target just slashed $500 off Samsung’s flagship soundbar, the HW-Q990D

The Samsung HW-Q990D soundbar will elevate your home theater setup's audio. It's expensive though, so don't miss this chance at a $500 discount from Target......»»

Category: topSource:  digitaltrendsRelated NewsSep 9th, 2024

Could alternative meat meet a growing demand?

Inside a UC Davis engineering lab, tiny round pellets swirl in a brown liquid inside a 5-liter glass tank. The tank, a bioreactor, is brewing edible fungi high in protein and designed to look and taste like meat......»»

Category: topSource:  theglobeandmailRelated NewsSep 9th, 2024

Researchers examine protein arrangement in cell membrane that triggers programmed cell death

How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from the fields of physics, chemistry and medicine at Heinrich Heine University Düsseldorf (HHU) have combined and further develo.....»»

Category: topSource:  physorgRelated NewsSep 9th, 2024

Scientists learn how to drug wily class of disease-causing enzymes

UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable.".....»»

Category: topSource:  physorgRelated NewsSep 9th, 2024

Glitch in protein synthesis could affect tumor growth

During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation machinery carouses along the string of nucleotides that m.....»»

Category: topSource:  theglobeandmailRelated NewsSep 9th, 2024

Beats Solo 4 headphones are on sale for a limited time

The Beats Solo 4 wireless headphones were just recently released, but you can purchase them for only $150 from Target following a limited-time $50 discount......»»

Category: topSource:  digitaltrendsRelated NewsSep 7th, 2024

Solving the side effect problem of siRNA drugs for genetic disease treatment

Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence genes other than the target ones, causing side eff.....»»

Category: topSource:  physorgRelated NewsSep 6th, 2024

Save $20 when you buy an Amazon Fire Stick this weekend

The Amazon Fire TV Stick 4K is a great inexpensive way to improve your streaming setup and it's on sale now at Target but for a limited time only......»»

Category: topSource:  digitaltrendsRelated NewsSep 6th, 2024

New Galileo satellites operational after successful in-orbit testing

Three months after their launch from Cape Canaveral, Galileo satellites 29 and 30 have reached their target positions at an altitude of 23,222 km, where they have been fully tested and declared operational......»»

Category: topSource:  physorgRelated NewsSep 5th, 2024

We gave this OLED TV a 9 out of 10, and it’s on sale today

The LG G4 Series is the TV we’d buy if we had all the dough in the world. To that end, the 55-inch model is actually on sale at Target this week!.....»»

Category: topSource:  digitaltrendsRelated NewsSep 5th, 2024

The popular LG C4 OLED TV has a huge price cut at Target

The LG C4 OLED is one of our favorite TVs in 2024, and Target is selling the 65-inch size for just $1,700 today!.....»»

Category: topSource:  digitaltrendsRelated NewsSep 5th, 2024

Algorithm maps protein degradation patterns to improve infection diagnosis and treatment

Peptides are small fragments of proteins, mainly found in the skin and mucous membranes. Some peptides act as a barrier, protecting the body against infections by fighting off microorganisms like bacteria, viruses, and other pathogens, while others p.....»»

Category: topSource:  physorgRelated NewsSep 5th, 2024

Researchers develop molecular biosensors that only light up upon binding to their targets

Biosensors—devices that use biological molecules to detect the presence of a target substance—have enormous potential for detecting disease biomarkers, molecules-in-action in diverse biological processes, or toxins and other harmful substances in.....»»

Category: topSource:  physorgRelated NewsSep 5th, 2024