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Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein

Recent failed clinical trials of a drug designed to clear the mutant Huntingtin protein that causes Huntington's disease (HD) heightens the need for new approaches for the devastating, incurable, progressive neurodegenerative genetic disorder. Scient.....»»

Category: biomedSource:  sciencedailyJun 3rd, 2021

GTA 5 for PS5 is just $20 at Target today

Grand Theft Auto V has been out for a minute, but now you can own the 2022 PS5 edition for only $20 when you purchase at Target!.....»»

Category: topSource:  digitaltrendsRelated NewsAug 30th, 2024

Our favorite TV deals in the Target Labor Day Sale

Target rolled out TV deals for its Labor Day Sale, with all the best TV brands. We've highlighted our favorite offers if you need help deciding what to buy......»»

Category: topSource:  digitaltrendsRelated NewsAug 30th, 2024

The best overall headphones of 2024 just got a $70 price cut at Target

The Sony WH-1000XM5 are the best headphones around and they're on sale now at Target making now the ideal time to buy......»»

Category: topSource:  digitaltrendsRelated NewsAug 30th, 2024

Scientists unlock the secrets of how a key protein converts DNA into RNA

Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»

Category: topSource:  physorgRelated NewsAug 29th, 2024

I just found this bass-heavy Vizio 20-inch home theater sound bar for $70

Want to improve your home cinema? Don't miss this Vizio 20-inch sound bar deal at Target. It's already priced competitively, more so with the discount......»»

Category: topSource:  digitaltrendsRelated NewsAug 29th, 2024

Target is selling Lenovo laptops for $150, with a catch

Buying refurbished laptops can save you a nice chunk of change, just like this phenomenal Target sale on the refurbished Lenovo IdeaPad Slim 3!.....»»

Category: topSource:  digitaltrendsRelated NewsAug 29th, 2024

Protein mutant stability can be inferred from AI-predicted structures

Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»

Category: topSource:  informationweekRelated NewsAug 29th, 2024

Study shows an electrically-activated protein regulates spermatogenesis

Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»

Category: topSource:  theglobeandmailRelated NewsAug 29th, 2024

Why ransomware attackers target Active Directory

Ransomware attacks have surged 78% year-over-year, affecting various sectors and organizations and significantly impacting supply chains. In this Help, Net Security video, Craig Birch, Technology Evangelist, and Principal Security Engineer at Cayosof.....»»

Category: securitySource:  netsecurityRelated NewsAug 29th, 2024

This is the best cheap tablet deal this back to school season

The 2023 release of the Amazon Fire HD 10, a cheap but dependable tablet for students, is on sale for $90 after a $50 discount from both Amazon and Target......»»

Category: topSource:  digitaltrendsRelated NewsAug 29th, 2024

This 24-inch Vizio is perfect for a spare room and it’s $130 today

The 24-inch Vizio D-Series LED is already inexpensive, and then Target went and knocked the price down by an extra $20!.....»»

Category: topSource:  digitaltrendsRelated NewsAug 29th, 2024

Chloroplast manipulation: A new strategy in pathogen warfare uncovered

A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»

Category: topSource:  physorgRelated NewsAug 28th, 2024

Simulation model shows ribosome tunnel"s impact on protein structures

Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»

Category: topSource:  physorgRelated NewsAug 28th, 2024

Expel partners with Wiz to enhance security for cloud environments

Expel announced a new strategic partnership with Wiz, a cloud-native application protection platform (CNAPP). The partnership provides an integration offering MDR for Wiz toxic risk combinations (including vulnerabilities, secrets, malware, and threa.....»»

Category: securitySource:  netsecurityRelated NewsAug 28th, 2024

APT group exploits WPS Office for Windows RCE vulnerability (CVE-2024-7262)

ESET researchers discovered a remote code execution vulnerability in WPS Office for Windows (CVE-2024-7262). APT-C-60, a South Korea-aligned cyberespionage group, was exploiting it to target East Asian countries. When examining the root cause, ESET d.....»»

Category: securitySource:  netsecurityRelated NewsAug 28th, 2024

Roku streaming devices are on sale at Target this week

The Roku Express 4K+ and the Roku Streaming Stick 4K are both on sale from Target. If you need a streaming device, you should take advantage of these deals......»»

Category: topSource:  digitaltrendsRelated NewsAug 27th, 2024

The basic Amazon Kindle has a rare discount at Target

The 2022 Amazon Kindle, which is the latest release of the basic model of the e-book reader, is on sale with a rare $15 discount from Target, but not for long......»»

Category: topSource:  digitaltrendsRelated NewsAug 27th, 2024

Target releases new CarPlay app with Drive Up order support

Target is rolling out its new CarPlay app this week. With this app, you can easily manage your Target Drive Up orders and find nearby Target locations using CarPlay. more….....»»

Category: topSource:  theglobeandmailRelated NewsAug 27th, 2024

Ford promotes EV design chief Todd Willing to global head of design

Ford tapped a 21-year veteran with global experience who led exterior design of the 2017 GT supercar to replace the recently departed Anthony Lo......»»

Category: topSource:  autonewsRelated NewsAug 27th, 2024

Save over $200 on this robot vacuum and mop with this Target deal

The Shark Matrix Plus robot vacuum and mop is an extremely helpful cleaning device that you can currently get for $480 from Target, following a $220 discount......»»

Category: topSource:  digitaltrendsRelated NewsAug 27th, 2024