Modifications to amino acids in sperm could be behind infertility
Sperm play a critical role in the creation of new life, delivering essentially half of the genetic material required......»»
Giant panda skin cells transformed into stem cells to help ensure their survival
A team of biologists in China has reprogrammed skin cells from giant pandas into induced pluripotent stem cells (iPSCs), opening the door to creating primordial germ cells that could serve as precursors to sperm and egg cells......»»
CRISPR/Cas9 modifies Euglena to create potential biofuel source
News about biofuels sometimes mentions used cooking oil as a feedstock, but if these substances contain animal fat, they can solidify in colder temperatures. This happens because, chemically, the fatty acids of these and many other saturated fats hav.....»»
Glitch in protein synthesis could affect tumor growth
During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation machinery carouses along the string of nucleotides that m.....»»
Compounds from nucleic acids in food show anticancer effects
When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor A.....»»
Tomato ripening study highlights cell wall component interactions
Tomato fruit ripening involves intricate biochemical and structural changes, particularly within the cell wall, which are vital for the fruit's final texture and quality. These changes include modifications in polysaccharides and proteins, but the sp.....»»
New genetic sensor for DNA methylation discovered
DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and is a major way that DNA is epigenetically marked. Epigenetic modifications can act as on–off switches to regulate gene expression and hel.....»»
Exploring bamboo charcoal"s slow-release properties for enhanced anti-acne formulations containing bamboo vinegar
Bamboo vinegar is a concentrated liquid obtained from bamboo under high temperature and anaerobic conditions. It contains more than 200 organic components, including organic acids, phenols, ketones, alcohols, and esters, among which acetic acid is th.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Researchers discover high levels of non-coding RNAs in testes, suggesting new roles in sperm function and evolution
Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had been previously esti.....»»
Researchers create ADP- or ATP-containing molecules with improved yield and consistency
Adenosine diphosphate (ADP) or adenosine triphosphate (ATP)-containing important biological molecules can modify macromolecules like proteins and nucleic acids to alter their function in the cell. Synthesizing ADP- and ATP-containing molecules using.....»»
New nanoparticle delivery method targets sickle cell mutations in bone marrow
Current gene therapies to treat sickle cell disease are complex, time-consuming, and are sometimes linked to serious side effects like infertility or blood cancer. To address these challenges, Johns Hopkins researchers have developed special nanopart.....»»
Signatures of life could survive near surfaces of the moons Enceladus and Europa, NASA experiment suggests
Europa, a moon of Jupiter, and Enceladus, a moon of Saturn, have evidence of oceans beneath their ice crusts. A NASA experiment suggests that if these oceans support life, signatures of that life in the form of organic molecules (e.g. amino acids, nu.....»»
Discovery of a tRNA modification enzyme that also acts on nucleosides
The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»
Asexual reproduction usually leads to a lack of genetic diversity. Not for these ants
Genetic diversity is essential to the survival of a species. It's easy enough to maintain if a species reproduces sexually; an egg and a sperm combine genetic material from two creatures into one, forming a genomically robust offspring with two disti.....»»
Team investigates chemical modifications to gain deeper insights into genetic regulation mechanisms
University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation, according to the paper, "Drosophila.....»»
Tiny TnpB: The next-generation genome editing tool for plants unveiled
Genome editing stands as one of the most transformative scientific breakthroughs of our time. It allows us to dive into the very code of life and make precise modifications. Imagine being able to rewrite the genetic instructions that determine almost.....»»
How to mitigate fraud on iOS devices using App Attest and DeviceCheck
App developers can minimize fraud by using App Attest and DeviceCheck, two tools provided by Apple. Here's how to use them to prevent unauthorized modifications to your app, and to prevent users from illegitimately acquiring premium content.App Attes.....»»
Photoenzymatic synthesis achieves efficient oxidation of fatty acids
A research team designed and built a photoenzymatic cascade by combining photochemical water oxidation/O2 reduction with P450 peroxygenase catalysis to achieve efficient visible-light-driven oxidation of a range of fatty acids (C12-C20), leading to p.....»»
AI approach optimizes development of antibody drugs
Proteins have evolved to excel at everything from contracting muscles to digesting food to recognizing viruses. To engineer better proteins, including antibodies, scientists often iteratively mutate the amino acids—the units that are arranged in a.....»»