Mechanisms of drug side effects uncovered
Researchers have discovered how drugs can affect various membrane-spanning proteins in addition to their intended target, potentially causing unwanted side effects. The results illuminate one of the central problems of drug discovery and point to new.....»»
Attacks on health care during war are becoming more common, creating devastating ripple effects
The head of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, has warned attacks on health-care workers, patients and facilities "must not become the norm.".....»»
The most common authentication method is also the least secure
Despite the rise in cyber threats, many people do not have a holistic view of security, according to Yubico. The results of the survey uncovered concerning patterns and behaviors when it comes to personal and workplace cybersecurity, including the ex.....»»
Geologists discover mysterious subduction zone beneath Pacific, reshaping understanding of Earth"s interior
University of Maryland scientists uncovered evidence of an ancient seafloor that sank deep into Earth during the age of dinosaurs, challenging existing theories about Earth's interior structure. Located in the East Pacific Rise (a tectonic plate boun.....»»
Exploring the role of hydrogen sulfide in the expression of iron uptake genes in E. coli
Antibiotic resistance and oxidative stress response are important biological mechanisms that help bacteria thrive, especially pathogenic bacteria like Escherichia coli. Hydrogen sulfide (H2S), a chemical messenger molecule, regulates several intracel.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
Seal species carries "genetic scars" after being hunted to the edge of extinction, new research reveals
Northern Elephant seals have staged a remarkable comeback after narrowly escaping extinction by hunting, but new research reveals lasting genetic effects in the present population......»»
Plant lineage study provides insights into the ecological and evolutionary effects of different reproductive strategies
Hang Sun's group from Kunming Institute of Botany, Chinese Academy of Sciences has demonstrated the ecological and evolutionary effects of changes in plant reproductive strategies on phylogenetic evolution. The study is published in the journal Scien.....»»
Future climate change predicted to shift flood-generating mechanisms and intensify extreme flooding events
The Delaware River Basin, a coastal watershed in the Mid-Atlantic region, has a long history of severe flooding with significant socioeconomic impacts. Recent research uses a process-based modeling approach to analyze hydrometeorological (like rainfa.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Advancing synthetic Ephedra-type alkaloids with a two-step enzymatic approach
Ephedra-type alkaloids, a class of naturally occurring compounds derived from plants in the genus Ephedra, have long held interest in the pharmaceutical industry due to their stimulant and airway widening effects. These alkaloids are used for the tre.....»»
Study reveals mallards" flight responses ineffective in preventing vehicle collisions
An article published in PeerJ Life & Environment has uncovered insights into how mallards (Anas platyrhynchos) respond to approaching vehicles, revealing that these common waterbirds are poorly equipped to avoid collisions, particularly at high speed.....»»
Thermal effects in spintronics systematically assessed for first time
Spintronics—devices that use microscopic magnetism in conjunction with electric current—could lead to computing technology as fast as conventional electronics but much more energy efficient. As such devices are developed and studied, an important.....»»
Neutron experiments settle 40-year debate on enzyme for drug design
In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers......»»
Researchers explore environmental impacts of genetically modified crops
Genetically modified (GM) crops are widely used around the world, but their effects on the environment need to be better understood......»»
Quantum sensing approach captures nanoscale electrochemical evolution in battery
Battery performance is heavily influenced by the non-uniformity and failure of individual electrode particles. Understanding the reaction mechanisms and failure modes at nanoscale level is key to advancing battery technologies and extending their lif.....»»
The Quest 3 may undergo a significant pricing change
With Meta Connect just a day away, leaks suggest that the launch of the Quest 3S could have major effects on the Quest 3 models......»»
65% of websites are unprotected against simple bot attacks
Companies across industries are seeing more bot-driven attacks, both basic and advanced, according to DataDome. An analysis of over 14,000 websites uncovered alarming gaps in protection against cyber fraud, particularly within consumer-centric indust.....»»
Gun violence in Philadelphia plummeted in 2024—researchers aren"t sure why, but here are 3 factors at play
Philadelphia experienced a surge in shootings and homicides during the COVID-19 years that disproportionately affected young Black and Latino men in economically disadvantaged neighborhoods with drug markets......»»
Can our stockpiles of Tamiflu protect against a bird flu pandemic?
Governments are banking on this old drug in the event of an H5N1 outbreak. Enlarge / A box and a tablet of Roche Pharmaceuticals' Tamiflu pills for influenza. (credit: Nikos Pekiaridis/NurPhoto via Getty Images) Since re.....»»
High-pressure reactions can turn nonporous rocks into sponges
In deep Earth, rocks take up and release water all the time, and the effects can be wide reaching. Dehydration can cause rocks to crack and trigger earthquakes, and over geologic timescales, this water cycling can influence plate tectonics and move c.....»»