Martynoside found to rescue 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A
Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic stem cells, and its disrupt.....»»
A glimpse into the formation of the mitoribosome
SciLifeLab Fellow Alexey Amunts and his team together with researchers from the Czech Academy of Sciences report an assembly intermediate of the ribosome in mitochondria. It reveals 22 associated factors that cooperatively organize the biogenesis pro.....»»
Dragonflies perform upside down backflips to right themselves
The findings add to current knowledge of how insects fly and keep stable in the air. They could also help to inspire new designs in small aerial vehicles like drones, which can be useful for search-and-rescue attempts and building inspection......»»
COVID-19 vs. conservation: How the northern white rhino rescue programme overcame challenges
The COVID-19 pandemic has changed the life of people everywhere and affected economic, cultural, social and political processes. Research and conservation are not exempt from these negative effects, whereas positive consequences of an 'anthropause' o.....»»
Changing cropping systems in impaired watersheds can produce water quality gains
Growing the right crop in the right place within an impaired watershed can achieve significant water quality improvements, according to Penn State researchers, who conducted a novel study in the drainage of a Susquehanna River tributary in an agricul.....»»
COVID-19 vs. conservation—how the northern white rhino rescue program overcame challenges
The BioRescue research project, a program aiming at saving the northern white rhinoceros from extinction, exemplifies the challenges to overcome when conducting research and conservation in an international consortium in times of a global pandemic. C.....»»
Researchers identify "rescue" mechanism that helps cells survive malfunctioning split
Cells replicate their genetic material and divide into two identical clones to perpetuate life. Some cells pause in the process with a single, undivided nucleus. When the cell resumes division after such a pause, the nucleus can become caught in the.....»»
Unlocking "the shape of water" in mechanisms of antibiotic resistance
New high-resolution structures of the bacterial ribosome determined by researchers at the University of Illinois Chicago show that a single water molecule may be the cause—and possible solution—of antibiotic resistance......»»
Facebook and Instagram’s AI-generated image captions now offer far more details
Every picture posted to Facebook and Instagram gets a caption generated by an image analysis AI, and that AI just got a lot smarter. The improved system should be a treat for visually impaired users, and may help you find your photos faster in the fu.....»»
To learn at home, kids need more than just teaching materials. Their brains must also adapt to the context
Research during the first phase of remote teaching in Victoria reported some students found the workload "too high," missed interactions with peers, felt their thinking ability was impaired, and reported a difficulty coping with study and life more g.....»»
Filling a crucial gap in aquafarming: Ion beam breeding to the rescue
A research team led by scientists at the RIKEN Nishina Center for Accelerator-Based Science (RNC) has successfully created larger-than-usual strains of zooplankton—which are used in fish nurseries—by creating mutations with a heavy ion beam. The.....»»
OneWeb has now raised $1.4B, with $400M from SoftBank and Hughes, to help fund its first satellite fleet
After a troubled year that saw broadband satellite operator OneWeb file for bankruptcy, get rescue finance from the UK government and Bharti, and then emerge out of that with a launch of part of its fleet last month, the London-based company today an.....»»
OneWeb picks up $1.4B more from SoftBank and Hughes to help fund its first satellite fleet
After a troubled year that saw broadband satellite operator OneWeb file for bankruptcy, get rescue finance from the UK government and Bharti, and then emerge out of that with a launch of part of its fleet last month, the London-based company today an.....»»
Indigenous peoples wary of UN biodiversity rescue plan
As crunch UN talks to reverse the accelerating destruction of nature loom, indigenous peoples are sounding an alarm over proposed conservation plans they say could clash with their rights......»»
Fluoride to the rescue? Addressing the challenge of antibiotic-resistant bacteria
Scientists have long been aware of the dangerous overuse of antibiotics and the increasing number of antibiotic-resistant microbes that have resulted. While over-prescription of antibiotics for medicinal use has unsettling implications for human heal.....»»
Imagine being blind and trying to attend a virtual event. Try that next time you stage one.
How do you make a virtual event accessible for people who are blind or visually impaired? When I started work on Sight Tech Global back in June this year, I was confident that we would find the answer to that question pretty quickly. With so many vir.....»»
Not even 5G could rescue smartphone sales in 2020
This was going to be the year of 5G. It was going to be the year the next-generation wireless technology helped reverse some troubling macro trends for the industry — or at the very least helped stem the bleeding some. But the best laid plans,.....»»
Detailed structure of ribosomes in nerve cells revealed
Protein synthesis is a finely tuned process in the cell by macromolecules known as ribosomes. Which regulators are responsible for controlling protein synthesis in the brain, and how do they exert their control on the ribosome? To address this questi.....»»
The pandemic helped me discover YouTube, and yes, I know I’m late to the party
Before 2020, I didn't watch YouTube very often, but when the pandemic struck, I found myself with plenty of time on my hands. YouTube came to my rescue......»»
Two dead as super cyclone levels Fiji villages
Super cyclone Yasa flattened entire villages as it tore through Fiji, aid agencies said Friday, with a baby among two confirmed deaths and rescue workers racing to the worst-hit communities......»»
Seeking to avoid "full lockdown," cells monitor ribosome collisions
Ribosomes are the machines in the cell that use instructions from mRNA to synthesize functional proteins. There are hundreds of thousands of ribosomes in each cell, and they mostly process their instructions faithfully. But sometimes ribosomes get st.....»»