Martynoside found to rescue 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A

Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic stem cells, and its disrupt.....»»