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Martynoside found to rescue 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A

Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic stem cells, and its disrupt.....»»

Category: topSource:  physorgAug 8th, 2023

Snakes in the city: Ten years of wildlife rescues reveal insights into human-reptile interactions

A new analysis of a decade-long collection of wildlife rescue records in NSW has delivered new insights into how humans and reptiles interact in urban environments......»»

Category: topSource:  physorgRelated NewsOct 1st, 2024

Nepal surveys flood wreckage as death toll reaches 209

Search and rescue teams in Nepal's capital picked through wrecked homes on Monday after waters receded from monsoon floods that killed at least 209 people around the Himalayan republic......»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

More than 60 dead from storm Helene as rescue, cleanup efforts grow

Rescuers struggled on Saturday with washed-out bridges and debris-strewn roads in the search for survivors of devastating Storm Helene, which killed at least 63 people across five states and caused massive power outages......»»

Category: topSource:  physorgRelated NewsSep 29th, 2024

59 dead in Nepal as downpours trigger floods

Floods and landslides triggered by heavy downpours in Nepal killed at least 59 people across the Himalayan country, with rescue teams searching for 44 missing, police said Saturday......»»

Category: topSource:  physorgRelated NewsSep 28th, 2024

SpaceX launches rescue mission to return stranded astronauts

A SpaceX rocket soared into the sky Saturday with two passengers on board, leaving two seats empty to return American astronauts who have been stranded for months on the International Space Station, NASA said......»»

Category: topSource:  physorgRelated NewsSep 28th, 2024

US hurricane deaths rise to 44, fears of more "catastrophic" flooding

At least 44 people died across five US states battered by powerful storm Helene, authorities said Friday, after torrential flooding prompted emergency responders to launch massive rescue operations......»»

Category: topSource:  physorgRelated NewsSep 28th, 2024

Genetic rescue for rare red foxes? Research uncovers options to restore Lassen red fox population

A rescue effort can take many forms—a life raft, a firehose, an airlift. For animals whose populations are in decline from inbreeding, genetics itself can be a lifesaver......»»

Category: topSource:  marketingvoxRelated NewsSep 26th, 2024

Tropical and subtropical industrial fisheries account for about 70% of methylmercury fished from the ocean: Study

Industrial fishing practices are increasing human exposure to methylmercury, a neurotoxicant associated with developmental delays in children and impaired cardiovascular health in adults......»»

Category: topSource:  physorgRelated NewsSep 24th, 2024

Harnessing exosomes and hydrogels for advanced diabetic wound healing

Diabetes, a widespread condition affecting approximately 13% of American adults, is often accompanied by complications such as impaired wound healing. If left unchecked, this can lead to severe outcomes, including the need for amputation......»»

Category: topSource:  physorgRelated NewsSep 20th, 2024

Fungi to the rescue: South African scientists use innovative approach to protect apple trees

Gardeners the world over dread the appearance of aphids on their plants. There are around 4,000 species of these sap-sucking insects and about 250 are pests that can wreak havoc on crops in a garden or orchard......»»

Category: topSource:  pcmagRelated NewsSep 17th, 2024

NASA admits tension with Boeing over space rescue plan

NASA admitted on Wednesday there was "tension" during meetings with Boeing executives about how to bring home two astronauts stranded on the International Space Station, but denied reports of shouting matches......»»

Category: topSource:  physorgRelated NewsSep 4th, 2024

Simulation model shows ribosome tunnel"s impact on protein structures

Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»

Category: topSource:  physorgRelated NewsAug 28th, 2024

Bayesian yacht disaster: How specialist search and rescue teams work underwater

Search and rescue for missing persons is always challenging for the specialist recovery teams involved, regardless of the environment they're working in......»»

Category: topSource:  physorgRelated NewsAug 24th, 2024

Russian pensioners urge Vladimir Putin to rescue Starliner astronauts

"They don't know how to get back. We ask you to help them." Enlarge / Screenshot from Putin's squad video on bringing Starliner's astronauts home. (credit: Putin's Squads Z Soc Sprav) One of the odder propaganda phenome.....»»

Category: topSource:  arstechnicaRelated NewsAug 20th, 2024

Surf spots are global ally in climate fight, study finds

A first-of-its-kind study, published today in Conservation Science and Practice, has found that the forests, mangroves and marshes surrounding surf breaks store almost 90 Mt (million metric tons) of climate-stabilizing "irrecoverable carbon," making.....»»

Category: topSource:  pcmagRelated NewsAug 12th, 2024

NASA weighs SpaceX rescue for stranded Boeing Starliner crew

What was meant to be a weeklong trip to the International Space Station (ISS) for the first NASA astronauts to fly with Boeing could extend to eight months, with the agency considering bringing them home on a SpaceX spaceship......»»

Category: topSource:  physorgRelated NewsAug 7th, 2024

iPhone’s Emergency SOS via satellite feature ‘literally saved their lives,’ rescue team says after wildfire left hikers stranded

A group of stranded hikers in British Columbia is crediting Apple’s Emergency SOS via Satellite feature for allowing them to call for help. As reported by the CBC, the hikers were stranded on a glacier after wildfires began to approach them—and t.....»»

Category: topSource:  pcmagRelated NewsJul 29th, 2024

Discovery of a tRNA modification enzyme that also acts on nucleosides

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»

Category: topSource:  physorgRelated NewsJul 18th, 2024

AMD just snatched the performance crown, even with an impaired Ryzen 9 9950X

An early sample of AMD's Ryzen 9 9950X has been tested, and it already manages to beat the Intel Core i9-14900KS......»»

Category: topSource:  digitaltrendsRelated NewsJul 18th, 2024

How Drones Are Revolutionizing Search and Rescue

As drones get less expensive and computer vision systems improve, rescuers are getting help from artificial eyes in the sky.....»»

Category: scienceSource:  sciamRelated NewsJul 10th, 2024