Martynoside found to rescue 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A
Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic stem cells, and its disrupt.....»»
Novel protein involved in mitochondrial gene expression identified
Researchers at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet have characterized a novel GTPase involved in ribosome production in mitochondria. The study, published in Nature Communications, provides new insights into.....»»
Whale had fishing lines "embedded" into body: Rescue took multiple days
A whale entangled in fishing gear was recently cut free by rescuers during a multiday operation off the coast of South Africa, video footage shows......»»
Carbon credits are useful for stabilizing the climate, but are they used effectively?
To have any chance of achieving the goal adopted in the Paris Agreement of stabilizing the global climate at less than 1.5°C above the pre-industrial average, humanity would have to become carbon neutral between 2050 and 2070 and show a negative car.....»»
Replanting trees can help prevent devastating landslides like the one in Papua New Guinea, but it"s not a silver bullet
More than 2,000 people are now feared dead after a huge landslide buried a village in the highlands of Papua New Guinea, Australia's nearest neighbor. Rescue efforts are being stymied by the fact the land is still sliding and moving. The disaster has.....»»
Research comes to the rescue to make firefighters" clothing safer
A pair of new University of Alberta studies show how to make firefighters' clothing safer to wear, maintain and manufacture......»»
He fell ill on a cruise. Before he boarded the rescue boat, they handed him the bill
He fell ill on a cruise. Before he boarded the rescue boat, they handed him the bill.....»»
Sonos has heard the music: VoiceOver improvements, local playback, and more return to new app
Sonos launched a brand-new version of its app this month. And it received lots of critical feedback from users over missing features, broken VoiceOver for vision-impaired users, and more. Now the company has acknowledged some of the problems and laun.....»»
New Sonos app breaks accessibility for visually impaired users, here’s what this advocate recommends
The new Sonos app launched today and was met with swift and intense backlash for removing many features and capabilities that long-standing customers value. While the company made an official statement on the matter, it hasn’t appeared to address a.....»»
Fish residues can compensate for raw materials shortages and improve our health in the bargain
More than a million tons of fish residues can rescue the food and cosmetic industries from raw materials shortages—and create new jobs. The key factors here are oils rich in omega-3, collagen and gelatin......»»
Brazil mounts frantic rescue effort as flooding kills at least 78
Authorities in southern Brazil scrambled Sunday to rescue people from raging floods and mudslides in what has become the region's largest ever climate catastrophe, with at least 78 dead and 115,000 forced from their homes......»»
Cold sintering may rescue plastic, ceramics, battery components from landfills
Recycling does not necessarily prevent an item from eventually ending up in a landfill, according to Enrique Gomez, interim associate dean for equity and inclusion and professor of chemical engineering in the Penn State College of Engineering. Instea.....»»
Study says California"s 2023 snowy rescue from megadrought was a freak event. Don"t get used to it
Last year's snow deluge in California, which quickly erased a two decade long megadrought, was essentially a once-in-a-lifetime rescue from above, a new study found......»»
How marketing classes can rescue "ugly produce" from becoming food waste
At a time of rising food costs and growing food insecurity, a large percentage of food grown for consumption never reaches our tables......»»
Hospital prices for the same emergency care vary up to 16X, study finds
Hospitals' "trauma activation fees" are unregulated and extremely variable. Enlarge / Miami Beach, Fire Rescue ambulance at Mt. Sinai Medical Center hospital. ] (credit: Getty | Jeffrey Greenberg/) Since 2021, federal la.....»»
Apple Watch fall detection helps rescue cyclist after crash during downpour
Apple Watch is a must-have accessory for every cyclist. That’s become time and again it has proven critical for helping cyclists after a crash. Eric Zollinger from New York is the latest wearer to know firsthand. more….....»»
A physicist uses X-rays to rescue old music recordings
Researchers are developing a technique that uses the special synchrotron X-ray light from the Swiss Light Source SLS to non-destructively digitize recordings from high-value historic audio tapes—including treasures from the Montreux Jazz Festival a.....»»
Netflix won’t make a Vision Pro app, so Supercut to the rescue
Apple Vision Pro is the best way to watch video, but Netflix hasn’t received the memo. Fortunately, young and aspiring developers are ready to show up and ship. Enter Christian Privitelli, the 19-year-old Australian developer of Supercut. more.....»»
Blind people can hear and feel April"s total solar eclipse with new technology
While eclipse watchers look to the skies, people who are blind or visually impaired will be able to hear and feel the celestial event......»»
Sawfish are spinning, and dying, in Florida waters as rescue effort begins
Endangered smalltooth sawfish, marine creatures virtually unchanged for millions of years, are exhibiting erratic spinning behavior and dying in unusual numbers in Florida waters. Federal and state wildlife agencies are beginning an effort to rescue.....»»
Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment
Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. During this phase, a cell's D.....»»