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Lipid epoxides target pain, inflammatory pathways in neurons

When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report. T.....»»

Category: biomedSource:  sciencedailyFeb 12th, 2021

Researchers develop database for catalytic bioparts with experimental evidence

Catalytic bioparts are fundamental to the design, construction and optimization of biological systems for specific metabolic pathways. A research team from the Chinese Academy of Sciences (CAS) has recently developed a Registry and Database of Biopar.....»»

Category: topSource:  physorgRelated NewsOct 17th, 2024

Electrophysiology study shows how ant toxin causes extreme pain

University of Queensland researchers have uncovered the workings of ant venom by measuring electric currents through individual channels in cells to understand how it causes pain......»»

Category: topSource:  physorgRelated NewsOct 17th, 2024

North Korean hackers use newly discovered Linux malware to raid ATMs

Once, FASTCash ran only on Unix. Then came Windows. Now it can target Linux, too. In the beginning, North Korean hackers compromised the banking infrastructure running AIX, IBM’.....»»

Category: topSource:  arstechnicaRelated NewsOct 15th, 2024

Scientists discover chemical probes for previously "undruggable" cancer target

Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»

Category: topSource:  informationweekRelated NewsOct 15th, 2024

New bacteria-based therapy shows promise for fighting cancer

Even as cancer remains a leading cause of death globally, bacteria-based cancer therapy presents an exciting and innovative treatment option. Owing to their ability to penetrate the rigid stromal barrier, bacteria can naturally target solid tumors an.....»»

Category: topSource:  physorgRelated NewsOct 15th, 2024

Study unveils cobalt(III) reaction mechanism with nitriles, opening pathways for drug development

A research team led by Professor Jaeheung Cho from the Department of Chemistry at UNIST has published a study in the Journal of the American Chemical Society reporting the reaction mechanism of cobalt(III)-based metal complexes with nitrile substance.....»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Scammers target Airbnb and Booking.com users

ESET researchers discovered that the organized scammer network Telekopye has expanded its operations to target users of popular accommodation booking platforms like Booking.com and Airbnb. They have also increased the sophistication of their victim s.....»»

Category: securitySource:  netsecurityRelated NewsOct 11th, 2024

Scientists accelerate uranium beam with record power

Scientists and engineers at the Facility for Rare Isotope Beams (FRIB) have reached a new milestone in isotope studies. They accelerated a high-power beam of uranium ions and delivered a record 10.4 kilowatts of continuous beam power to a target. The.....»»

Category: topSource:  physorgRelated NewsOct 10th, 2024

Simbian unveils AI Agents to address the top pain points for SOC analysts

Simbian announced a suite of AI Agents that work alongside security teams to enhance the intelligence, speed, and coverage of their entire security program. The suite of AI Agents, which runs on the Simbian Security Accelerator Platform, addresses th.....»»

Category: securitySource:  netsecurityRelated NewsOct 10th, 2024

Best Target Prime Day deals: Our favorite Circle Week deals to shop right now

With the discounts that you can get from these Target Prime Day deals, you'll be able to buy a TV or other appliance for your home for much cheaper than usual......»»

Category: topSource:  digitaltrendsRelated NewsOct 8th, 2024

Study reveals relationship between nitrogen-cycling microbial communities and nitrogen removal

Excess nitrogen (N) input to the inland water bodies and marine ecosystem has contributed to a cascade of environmental issues, so N removal pathways are critical in aquatic and terrestrial ecosystems for maintaining homeostasis. Associated functiona.....»»

Category: topSource:  physorgRelated NewsOct 8th, 2024

Samsung says it’s in “crisis,” apologizes for missing profit target

Performance has not met expectations as company tries closing fab gap with TSMC. Samsung Electronics has issued a public apology and acknowledged the company is considered to be i.....»»

Category: topSource:  informationweekRelated NewsOct 8th, 2024

FAA gives SpaceX the OK to launch just one Falcon 9 on asteroid mission for Europe

The Federal Aviation Administration on Sunday announced it was approving just one SpaceX Falcon 9 mission, although SpaceX has submitted its mishap report into why the second stage from last week's Crew-9 mission failed to hit its planned target on r.....»»

Category: topSource:  theglobeandmailRelated NewsOct 7th, 2024

100+ domains seized to stymie Russian Star Blizzard hackers

Microsoft and the US Justice Department have seized over 100 domains used by Star Blizzard, a Russian nation-state threat actor. “Between January 2023 and August 2024, Microsoft observed Star Blizzard target over 30 civil society organizations.....»»

Category: securitySource:  netsecurityRelated NewsOct 4th, 2024

Study: Wildfires will make the land absorb much less carbon, even if warming is kept below 1.5°C

One of the aims of the Paris Agreement was to "pursue efforts" to keep global warming below 1.5°C, but even this ambitious target would not stop the land's ability to absorb carbon weakening as wildfires become fiercer and more frequent, according t.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Private US companies targeted by Stonefly APT

Undeterred by the indictment issued against one of its alleged members, North Korean APT group Stonefly (aka APT45) continues to target companies in the US, Symantec threat analysts warned. About Stonefly Also known as Andariel and OnyxFleet, Stonefl.....»»

Category: securitySource:  netsecurityRelated NewsOct 3rd, 2024

AI model detects impervious surfaces in aerial images

In accordance with the German Sustainability Strategy, new impervious surfaces are to be limited to less than 30 hectares per day nationwide. In order to verify whether this target is met, it must be possible to monitor soil sealing at regular interv.....»»

Category: topSource:  physorgRelated NewsOct 1st, 2024

Seeing double: Designing drugs that target "twin" cancer proteins

Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»

Category: topSource:  physorgRelated NewsOct 1st, 2024

3D structure of key protein could advance development of hormone-free male contraceptive pill

Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»

Category: topSource:  theglobeandmailRelated NewsOct 1st, 2024

Indigenous US farm workers face greater job-related pain compared to undocumented peers, study suggests

Farming is a notoriously hard profession with long hours spent operating dangerous equipment and performing other arduous tasks. New Rice University research finds that Indigenous farm employees—many of whom have legal status in the U.S. after movi.....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024