Is the Psychedelic Therapy Bubble About to Burst?
A new paper argues that excitement has veered into misinformation—and scientists should be the ones to set things straight......»»
Lifesaving gene therapy for kids is world’s priciest drug at $4.25M
It's unclear if government and private insurance plans can cover the costs. Enlarge / A mother with her twin 6-year-old boys who have metachromatic leukodystrophy, a genetic disease that leaves them unable to move. Photo taken on.....»»
Advances and applications of nanoparticles in cancer therapy
The research team of Prof. Changyang Gong from the Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University has published a new review showing that rapid growth in nanoparticles as delive.....»»
Research seeks to develop mRNA lipid nanoparticles for next-generation oral cancer tumor suppressor therapy
A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of t.....»»
In vivo production of CAR-T cells using virus-mimetic fusogenic nanovesicles
Chimeric antigen receptors (CARs) are synthesized membrane proteins that enable lymphocytes to recognize and respond to the specific antigens of target cells. Despite the impressive efficacy of CAR-T cell therapy in treating B-cell lymphoma or leukem.....»»
Using adavosertib-encapsulated MOFs for p53-mutated gallbladder cancer treatment via synthetic lethality
Since the revelation of poly(ADP-ribose) polymerase (PARP) inhibitors and their remarkable results in the treatment of BRCA1/2 mutant cancers, synthetic lethality (SL) in antitumor therapy has attracted increasing attention. SL is a phenomenon in whi.....»»
Engineered MgO nanoparticles: A promising path to synergistic cartilage and bone therapy
In a recent study published in Science Advances, researchers from Nanjing Drum Tower Hospital and others have unveiled a promising approach for treating osteoarthritis (OA) using engineered magnesium oxide (MgO) nanoparticles......»»
Q&A: Bringing forest therapy indoors can improve your health
For centuries, people have found solace in walks through the forest and the practice of "forest bathing." Now, researchers at UBC are delving into the science behind this tradition to understand its benefits better and make them accessible to all......»»
Tsetse fly fertility damaged after just one heat wave, study finds
The fertility of both female and male tsetse flies is affected by a single burst of hot weather, researchers at the University of Bristol and Stellenbosch University in South Africa have found......»»
Team achieves successful mass production of metalenses designed for application in the ultraviolet region
Ultraviolet rays find diverse applications in medical and health care, serving purposes such as disinfection, sterilization, and therapy. They are also used in the semiconductor industry for creating microcircuits and patterns......»»
Gender bias leads to lower-rated female films, researchers say
"Barbie" might have won the dance-off against "Oppenheimer" at the box office, but a new Robert H. Smith School of Business study may explain why the hot-pink bubble burst well before this Oscar weekend......»»
You need to try PlayStation VR2’s most psychedelic game yet
If you need a good reason to dust off your PlayStation VR2, you'll want to check out the psychedelic Akka Arrh......»»
Lipid nanoparticles research closing in on genetic treatments for hereditary lung disease, vision loss
Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and in.....»»
Was F1 too boring? Watch these races instead
F1 might be a foregone conclusion, but F2 and the WEC should thrill and delight. Enlarge (credit: Getty Images) Formula 1's 2024 season burst into action this past weekend at the Bahrain Grand Prix. The 10 teams had just.....»»
Hydrogel spheres compose a microporous structure for localized mRNA delivery
In a significant leap forward in the realm of regenerative medicine, a team at the Terasaki Institute for Biomedical Innovation has introduced a pioneering approach to mRNA therapy using microspheres made of gelatin methacryloyl (GelMA)—a gelatin-b.....»»
Nanotweezers manipulate bacteriophages with minimal optical power, a breakthrough for phage therapy
Scientists at EPFL have developed a game-changing technique that uses light to manipulate and identify individual bacteriophages without the need for chemical labels or bioreceptors, potentially accelerating and revolutionizing phage-based therapies.....»»
Further study of bright gamma-ray burst GRB 230307A shows it was caused by neutron stars merging
An international team of astronomers and astrophysicists has found evidence that the bright gamma-ray burst GRB 230307A observed last year was caused by two neutron stars merging, not from a collapsing massive star. In their study, published in the j.....»»
LHAASO discovers giant ultra-high-energy gamma-ray bubble, identifying the first super PeVatron
The Large High Altitude Air Shower Observatory (LHAASO) has discovered a giant ultra-high-energy gamma-ray bubble structure in the Cygnus star-forming region, which is the first time that the origin of cosmic rays with energy higher than 10 Peta-Elec.....»»
Damage to cell membranes causes cell aging, finds new study
Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury. To cope with such damage, cells are equipped w.....»»
Junk DNA in birds may hold key to safe, efficient gene therapy
The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes into the human genome to.....»»
Study finds new inhalable therapy is a big step forward in lung cancer research
Lung cancer is one of the most common cancers and has one of the lowest survival rates in the world. Cytokines, which are small signaling proteins, such as interleukin-12 (IL-12), have demonstrated considerable potential as robust tumor suppressors......»»