Investigating the druggability of SARS-CoV-2 nucleocapsid protein RNA interactions
The Allain (IBC), Gossert (BNSP) and Leitner (IMSB) groups investigated the druggability of the SARS-CoV-2 Nucleocapsid protein RNA interactions by a hybrid structure determination approach, which led to the identification of primary fragment hits. T.....»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
Dell confirms it is investigating data breach after employee info leaked
A hacker says they stole employee info on more than 10,000 people and Dell is currently looking into it......»»
iPhone 16 Pro users experiencing touchscreen issues, some taps and swipes ignored
An increasing number of iPhone 16 Pro owners are reporting intermittent issues with their phone’s touchscreen responsiveness. Users experience taps and swipes seemingly being ignored, which affects various interactions like scrolling, pressing butt.....»»
Man dies days after e-scooter hit-and-run in Koreatown; police investigating
Man dies days after e-scooter hit-and-run in Koreatown; police investigating.....»»
New biosensor illuminates physiological signals in living animals
Eric Schreiter and Luke Lavis thought they had figured it out. In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Genetic tracing at the Huanan Seafood market further supports COVID animal origins
A new international collaborative study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of meta.....»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
“Dead Internet theory” comes to life with new AI-powered social media app
SocialAI takes the social media "filter bubble" to an extreme with 100% fake interactions. Enlarge (credit: gremlin via Getty Images) For the past few years, a conspiracy theory called "Dead Internet theory" has picked u.....»»
Recent PS5 firmware update may have caused big issues in some games
Square Enix is investigating a possible PS5 issue that made its game Final Fantasy 16 unplayable for some users......»»
How job-hopping managers undermine corporate culture
As most successful companies will know, building effective corporate culture is very rewarding, but also challenging. It requires senior managers to create shared values and embed those values in their decisions and interactions with staff......»»
An unexpected protein connection in maize growth and defense could enhance crop resilience
Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored......»»
Team discovers naturally occurring DNA-protein hybrids
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»
Leveraging body-camera footage to analyze police training impact
A study used body-worn camera footage as a source of data on police-community interactions. Nicholas Camp and colleagues analyzed transcripts from 615 police stops made in California by Oakland Police Department police officers before and after a pro.....»»
Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»
What killed fish for miles in the South River? Atlanta officials are investigating
Officials are investigating a pollution incident that occurred earlier this month a few miles south of downtown Atlanta, which local water advocates say sent toxins into a tributary of the South River and killed fish for miles downstream......»»
Technique to study how proteins bind to DNA is easily misused: Researchers offer a solution
Researchers at University of California San Diego have published new guidelines that could help scientists significantly improve their results when quantifying the interactions between DNA and proteins. Understanding these interactions is critical to.....»»
Edible insects show promise as sustainable nutritional source
As the global population grows and traditional livestock production increasingly strains environmental resources, there is a rising interest in alternative protein sources. Edible insects, particularly grasshoppers, are abundant in regions like Camer.....»»
Study shows plant-derived secondary organic aerosols can act as mediators of plant-plant interactions
A study published in Science reveals that plant-derived secondary organic aerosols (SOAs) can act as mediators of plant-plant interactions. This research was conducted through the cooperation of chemical ecologists, plant ecophysiologists and atmosph.....»»