Interdisciplinary approach provides new insights into molecular mechanisms of cholera infection
Cholera infections caused by Vibrio cholerae bacteria can be life-threatening and the trigger is the cholera toxin produced by the bacteria. It binds to the surface of intestinal cells—more precisely, to certain "sugar lipids" (GM1 gangliosides, GM.....»»
Path of Exile 2 bugs making you feel exiled? Fixes are on the way
Path of Exile 2 is now out in early access, but it was a bumpy start. The team at Grinding Gear Games have laid out their approach to fixing the bugs......»»
Brian Cox still isn’t sure about Jeremy Strong’s method acting approach
The actor has maintained that he thinks his former co-star would be a better actor if he ditched the method approach......»»
Hybrid model links micro and macro scales in complex systems
In fields ranging from immunology and ecology to economics and thermodynamics, multi-scale complex systems are ubiquitous. They are also notoriously difficult to model. Conventional approaches take either a bottom-up or top-down approach. But in dist.....»»
Analysis provides new insights into the replication of BK polyomavirus, a major cause of kidney transplant failure
BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research at the University of Alabama at Birmingham reveals new aspects of BKPyV replication, offering possible drug targets to pro.....»»
Detecting problems during protein synthesis with a firefly luciferase-based reporter
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo. Inspired by natural mechanisms found in bacteria, th.....»»
Digital twin model enables precise simulation of forest landscapes, depicting a forest in 100 years
Forest ecosystems of the future will have to cope with very different conditions to those of today. For this reason, researchers at the Technical University of Munich (TUM) state that a strategic approach to forest management is crucial. To this end,.....»»
Interdisciplinary research reveals impressive adaptation mechanisms of microscopic algae
Researchers from the University of Jena and the Leibniz Institutes in Jena have published new findings on the adaptability of the microalgae Chlamydomonas reinhardtii. The interdisciplinary study, largely carried out by scientists from the Cluster of.....»»
Apple"s iPhone 17 Slim is a wrongheaded approach that ignores what people really want
Rumors continue to swirl that Apple will launch a new iPhone 17 Slim in 2025. Why does Apple think anyone wants it?A render of what the iPhone 17 Slim could look likeIn a world where people want their devices to last for longer than ever on a single.....»»
Experiments provide evidence that interaction of light with a hydrocarbon molecule produces strained molecular rings
When molecules interact with ultraviolet (UV) light, they can change shape quickly, producing strain—stress in a molecule's chemical structure due to an increase in the molecule's internal energy. These processes typically take just tens of picosec.....»»
Scientists identify mutation that could facilitate H5N1 bird flu virus infection and potential transmission in humans
Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one change can increase the risk of becoming a pandemic virus?.....»»
Spectroscopy and AI method provide unique window into protein structure and mechanism of action
The lab of Hassane Mchaourab, director of the Center for Applied Artificial Intelligence in Protein Dynamics and professor of molecular physiology and biophysics, has developed a methodological blueprint that couples experimental double electron–el.....»»
New research explores social dimension of sustainable diets
New research supported by the Interdisciplinary Research Innovation Fund (RAFINS) at the Friedman School highlights an often overlooked aspect of sustainable diets research: How the production and consumption of food impacts people, communities, and.....»»
Four months of camera collar footage provide unprecedented insights into the lives of threatened Andean bears
A team of wildlife ecologists at Asociación para la Conservación de la Cuenca Amazónica, in Peru, working with a colleague from the Osa Conservation, in the U.S., has recorded four months of previously undocumented natural behaviors of Andean bear.....»»
Middesk Address Risk Insights strengthens onboarding processes
Middesk introduced Address Risk Insights, a critical new addition to its core Know Your Business (KYB) product Verify and its recently introduced risk scoring Signal product. A first for the KYB space, Address Risk Insights helps companies assess the.....»»
A path towards applying topology in quantum computing
Can insights from topology—the study of the properties of 3D objects that persist when an object is stretched or compressed—be applied in the field of quantum information processing? Juan Lin, Shou-Bang Yang, Fan Wu, and Zhen-Biao Yang, researche.....»»
A key transcription factor unlocks new potential in stem cell-based embryo models
Researchers from the A*STAR Institute of Molecular and Cell Biology (IMCB) have identified Nr1h2, a critical transcription factor essential for early embryo development. Published in Nature Communications, their findings enhance our understanding of.....»»
AI model enables reliable and accurate protein-ligand complex prediction
Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the heart of many cellular processes, from enzyme catalysis to signal transduction. The foundational knowledge of protein–li.....»»
Discovery of molecular switch explains how bacteria control their protein biosynthesis through cell metabolism
Protein biosynthesis—the process whereby cells produce protein molecules, which are essential for life and growth—is a highly complex and strictly regulated affair. An interdisciplinary team led by LMU biologist PD Dr. Jürgen Lassak has now disc.....»»
Children"s toys offer insights into cultural adaptation in Little Ice Age Greenland
A study published in the European Journal of Archaeology by Ph.D. candidate Mathilde Vestergaard Meyer and Dr. Felix Riede explores the contribution of children's toys in coping with environmental change in Greenland during the Little Ice Age......»»
New catalyst can convert methane into useful polymers
Although it is less abundant than carbon dioxide, methane gas contributes disproportionately to global warming because it traps more heat in the atmosphere than carbon dioxide, due to its molecular structure......»»