Immune function remodeled by mitochondrial shape
A new study focused on the immune system's Th17 cells suggests that the shape and function of their mitochondria is important in autoimmune and inflammatory disorders, such as multiple sclerosis. T helper 17 (Th17) cells are a type of CD4+ T immune c.....»»
Surprise finding in study of environmental bacteria could advance search for better antibiotics
In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial.....»»
Revealing the mysteries within microbial genomes with a new high-throughput approach
A new technique developed at Lawrence Berkeley National Laboratory (Berkeley Lab) will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the role.....»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
Waste into gold: Oyster shells repurposed as magic "Seawool"
Growing up on Taiwan's west coast where mollusk farming is popular, Eddie Wang saw discarded oyster shells transformed from waste to function—a memory that inspired him to create a unique and environmentally friendly fabric called "Seawool"......»»
Genetic study uncovers onion bulb shape, size secrets
A new study by the Department of Plant and Agroecosystem Sciences, University of Wisconsin details the genetic mechanisms influencing the shape and volume of onion bulbs, along with the effects of daylength on the bulbing process. This research provi.....»»
Technology to predict the deformation of DNA origami structures induced by DNA-binding molecules
A research team has developed a technology that can quickly predict the mechanochemical shape changes of DNA origami nanostructures. The team includes Professor Do-Nyun Kim's research team from the Department of Mechanical Engineering at The College.....»»
DNA Topoisomerase insights hold potential for drug discovery and plant protection
Insights into the function of DNA Topoisomerase VI (Topo VI) may provide a springboard for drug discovery and crop protection......»»
Image: Upper Lake Powell area in Utah
Erosion, tectonic uplift, and a human-built dam have all helped shape the Upper Lake Powell area in Utah......»»
Male and female lions socialize differently throughout their lives, study reveals
New research from the University of Oxford on wild lions has revealed that males and females experience vastly different changes to their social network throughout their lives, and that this may shape their survival......»»
GM’s new Detroit headquarters is taking shape — but don’t overlook revamped Warren Tech Center
GM, which is leaving the Renaissance Center to be the marquee office tenant of the new $1.4 billion Hudson’s development, will build out an “indoor/outdoor showroom” at the Woodward Avenue site......»»
"Miseries of the Balkhash": Fears for Kazakhstan"s magical lake
Seen from the sky, with its turquoise waters stretching out into the desert expanses in the shape of a crescent, you can see why they call Lake Balkhash the "pearl of Kazakhstan"......»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
A Band-Aid for the heart? New 3D printing method makes this, and much more, possible
In the quest to develop life-like materials to replace and repair human body parts, scientists face a formidable challenge: Real tissues are often both strong and stretchable and vary in shape and size......»»
Hidden players in climate change: How microscopic proteins could shape our future
In the narrative about climate change, we often focus on the big and visible—like shrinking glaciers and churning hurricanes. But there's another world, microscopic and hidden, that's just as crucial and the focus of a new study by Amy Gladfelter,.....»»
Atmospheric rivers shape long-term changes in Arctic moisture variability
Recent decades have seen rapid warming in the Arctic, known as Arctic amplification, which has impacted the Arctic's cryosphere and ecosystems and influenced global weather and climate through changes in atmospheric circulation......»»
Researchers discover high levels of non-coding RNAs in testes, suggesting new roles in sperm function and evolution
Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had been previously esti.....»»
Study identifies universal blueprint for mammalian brain shape
Researchers have developed a new approach for describing the shape of the cerebral cortex, and provide evidence that cortices across mammalian species resemble a universal, fractal pattern......»»
ACE-ing protein detection in single cells
Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals. This has enabled a much deep.....»»
How bacteria attach their cloaks of invisibility to immune defenses
Bacteria have different strategies for protecting themselves. Some bacterial pathogens surround themselves with a shell made of many sugar chains that lie close together, also known as capsular polymers. This protects the bacteria from drying out and.....»»