How talin protein maintains intercellular connection while transmitting force
In multicellular organisms, cell migration and mechanosensing are essential for cellular development and maintenance. These processes rely on talin, the key focal adhesion—or FA—protein, central in connecting adjacent cellular matrices and enabli.....»»
MicroRNA, Protein Folding and Machine-Learning Work Win the Science Nobels
A roundup of the science Nobels, the latest COVID updates and the Europa Clipper launch delay......»»
Australia is going to more than double the size of Ukraine"s Abrams tank force
Australia is going to more than double the size of Ukraine"s Abrams tank force.....»»
Over 40 missing children found in Erie County by national task force, local law enforcement
Over 40 missing children found in Erie County by national task force, local law enforcement.....»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
Bacteria discovered in healthy vertebrate brains point to a potential role in brain function
Researchers at the University of New Mexico have identified the presence of bacteria in the healthy brains of fish. Understanding this connection between bacteria and animal brains could have future implications for the study of Alzheimer's disease......»»
Glowing proteins enable real-time, 3-D study of essential enzymes
Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival. Malfunction o.....»»
Calcium transport protein in bacteria offers insights for drug development and food safety
Researchers at Umeå University have revealed details on how bacteria use calcium to regulate vital processes in a way that differs from human cells. This breakthrough is significant in the fight against antibiotic resistance and for increasing safet.....»»
Protein USP50 identified as key in DNA replication balance
A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study......»»
Expansion in situ genome sequencing innovation makes hidden DNA-protein interactions visible
Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The innovation allowed researchers to link nucleus abnormaliti.....»»
Can walls of oysters protect shores against hurricanes? Darpa wants to know.
Colonized artificial reef structures could absorb the power of storms. On October 10, 2018, Tyndall Air Force Base on the Gulf of Mexico—a pillar of American air superiority—f.....»»
Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry
The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»
"Killer electrons": Lightning storms play cosmic pinball with space weather
When lightning strikes, the electrons come pouring down. In a new study, researchers at the University of Colorado Boulder, led by an undergraduate student, have discovered a novel connection between weather on Earth and space weather. The team utili.....»»
Targeting "undruggable" diseases: Researchers reveal new levels of detail in targeted protein degradation
Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and ne.....»»
Oxidative stress: How protein recycling protects against cell death
Researchers at LMU University Hospital have discovered a new molecular switch that protects against cell death......»»
Scientists discover how innate immunity envelops bacteria
The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now......»»
Rocket Report: ULA investigating SRB anomaly; Europa Clipper is ready to fly
US Space Force payloads will ride on the first flight of Impulse Space's cryogenic space tug. Welcome to Edition 7.15 of the Rocket Report! It's a big week for big rockets, with S.....»»
Zoom debuts its new customizable AI Companion 2.0
Zoom unveiled its next-generation AI assistant for Workplace that promises to deliver an AI-first work platform for human connection......»»
AI-driven approach challenges traditional views on protein structure
In a recently published article in Nature Communications,, a team offers an AI-driven approach to explore structural similarities and relationships across the protein universe. The team includes members from the University of Virginia—including Phi.....»»
Dark energy: Could the mysterious force we think of as constant actually vary over cosmic time?
,As I finished my Ph.D. in 1992, the universe was full of mystery—we didn't even know exactly what it is made of. One could argue that cosmologists had made little progress in our understanding of these basic facts since the discovery of the cosmic.....»»
Hurricane Milton shreds Florida stadium roof
Hurricane-force winds ripped open the roof of a baseball stadium in Florida, leaving shredded remnants of the dome in its wake Thursday morning......»»