How inflammatory signalling molecules contribute to carcinogenesis
Researchers have managed to identify a previously unknown molecular connection between an inflammatory signalling molecule and one of the main oncogenes......»»
The secret to sleepy cells" control of inflammatory secretions
Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells. This drowsy condition is known to provide heal.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
AI tackles one of the most difficult challenges in quantum chemistry
New research using neural networks, a form of brain-inspired AI, proposes a solution to the tough challenge of modeling the states of molecules......»»
Novel silica nonwoven fabric scaffold enhances understanding of cell-to-cell interactions
Communication and coordination among different cells are fundamental aspects that regulate many functions in our body. This process, known as paracrine signaling, involves the release of signaling molecules by a cell into its extracellular matrix (EC.....»»
First visualization of valence electrons reveals fundamental nature of chemical bonding
The distribution of outermost shell electrons, known as valence electrons, of organic molecules was experimentally observed for the first time by a team led by Nagoya University in Japan. As the interactions between atoms are governed by the valence.....»»
From embers to crisis: The expanding threat of wildfires under global warming
Globally, wildfires are on the rise, driven by climate change, which exacerbates droughts and high temperatures. These fires contribute significantly to carbon emissions and particulate matter (PM2.5), with severe consequences for both climate stabil.....»»
Researchers shed light on how to make photopolymerization much more efficient
Polymers are materials made out of long, repeating chains of molecules, and it is the interaction between these chains that dictates most of a polymer's physicochemical properties. In accordance with this intuitive understanding of polymers, which da.....»»
Peering into the mind of artificial intelligence to make better antibiotics
Artificial intelligence (AI) has exploded in popularity. It powers models that help us drive vehicles, proofread emails and even design new molecules for medications. But just like a human, it's hard to read AI's mind......»»
Research reveals pharmaceuticals are polluting England"s National Parks
Research from the University of York and the Rivers Trust has revealed widespread contamination of rivers in the parks, with antidepressants, anticonvulsants, antimicrobials, anti-inflammatory substances, lipid regulators and diabetes treatments bein.....»»
New cobalt complex triggers ferroptosis in cancer cells
In programmed cell death, certain signaling molecules initiate a kind of suicide program to cause cells to die in a controlled manner. This is an essential step to eliminate damaged cells or to control the number of cells in certain tissues, for exam.....»»
Research team finds evidence of hydration on the asteroid Psyche
Using data from NASA's James Webb Space Telescope, a Southwest Research Institute-led team has confirmed hydroxyl molecules on the surface of the metallic asteroid Psyche. The presence of hydrated minerals suggests a complex history for Psyche, impor.....»»
Common equine painkiller disrupts assisted reproduction technique efficiency in mares
Researchers at the Texas A&M School of Veterinary Medicine & Biomedical Sciences (VMBS) have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells—.....»»
A hopper could explore more than 150 km of Triton"s surface in two years
Neptune's largest moon, Triton, is one of the most biologically interesting places in the solar system. Despite being hard to reach, it appears to have active volcanoes, a thin atmosphere, and even some organic molecules called tholins on its surface.....»»
Wobbly molecules closer look with a new theoretical framework
While new technologies, including those powered by artificial intelligence, provide innovative solutions to a steadily growing range of problems, these tools are only as good as the data they're trained on......»»
New surfactant from cashew nut shell liquid boosts industrial reactions
Industries and chemical labs synthesize a wide variety of organic molecules every day. Most of these chemical reactions happen in the liquid phase to allow the substrates to interact easily. However, many substrates and catalysts are sensitive to wat.....»»
A new robotic platform to reproduce and study complex ciliary behavior
Cilia are sensory structures extending from the surface of some cells. These hair-like structures are known to contribute to the sensorimotor capabilities of various living organisms, including humans......»»
Research team uses tunable laser to develop straightforward broadband spectroscopy method with Hz-level precision
Since the first demonstration of the laser in the 1960s, laser spectroscopy has become an essential tool for studying the detailed structures and dynamics of atoms and molecules. Advances in laser technology have further enhanced its capabilities. Th.....»»
Chemists synthesize plant-derived molecules that hold potential as pharmaceuticals
MIT chemists have developed a new way to synthesize complex molecules that were originally isolated from plants and could hold potential as antibiotics, analgesics, or cancer drugs......»»
PhAI—an AI system that figures out the phase of x-rays that crystals have diffracted
A trio of chemists at the University of Copenhagen has developed an AI application that can be used to figure out the phase of x-rays that crystals have diffracted as part of efforts to predict the structure of small molecules......»»
Technology to predict the deformation of DNA origami structures induced by DNA-binding molecules
A research team has developed a technology that can quickly predict the mechanochemical shape changes of DNA origami nanostructures. The team includes Professor Do-Nyun Kim's research team from the Department of Mechanical Engineering at The College.....»»