How hydrophobicity shapes protein assemblies
Through a nuanced balance of electrical and hydrophobic forces, biological molecules self-assemble into the large functional structures that maintain life's vital functions. Understanding how proteins self-assemble requires knowledge of both forces......»»
Newly discovered protein stops DNA damage
Researchers from Western University have discovered a protein that has the never-before-seen ability to stop DNA damage in its tracks. The finding could provide the foundation for developing everything from vaccines against cancer, to crops that can.....»»
Surprise finding in study of environmental bacteria could advance search for better antibiotics
In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial.....»»
How color shapes which animals we fear—and which we protect
Around the world, animals that exhibit rare color morphisms—including lighter-colored variants with albinism or leucism and dark-colored variants with melanism—are often the subject of both veneration and fear in humans......»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
Study finds protein reduces toxicity of graphene oxide for drug delivery
A new study has discovered ways to reduce the toxicity of graphene oxide (GO), an ultra-thin sheet of nanomaterial derived from graphite, laying the groundwork to use it as a drug delivery system......»»
International team discovers key protein that helps cells maintain their identity
A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell. The discovery is the result of an international research collaboration, led by Professors Genevieve.....»»
Researchers identify body"s "quality control" regulator for protein folding, could lead to targeted treatments
Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
A new mechanism for shaping animal tissues
A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, Germany, the Exce.....»»
The molecular shield: How tea plants combat drought through protein phosphorylation
Drought stress poses a significant challenge to agriculture, causing substantial yield losses in many crops. Tea plants, known for their rich flavonoid content which enhances both quality and health benefits, are particularly affected. Under drought.....»»
Researchers develop AI model that predicts the accuracy of protein–DNA binding
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the t.....»»
Largest protein yet discovered builds algal toxins
While seeking to unravel how marine algae create their chemically complex toxins, scientists at UC San Diego's Scripps Institution of Oceanography have discovered the largest protein yet identified in biology......»»
Heat stress survival: Unraveling the HsfA2-ACTIN dynamics in lily varieties
A research team has identified that the heat stress transcription factor HsfA2 and actin-interacting protein (AIP) LACTIN interact at the protein level in Lilium longiflorum "White Heaven," mediating gene expression and protecting cells from heat str.....»»
A review of the Epichloë festucae antifungal protein Efe-AfpA
A research team has reviewed the mechanisms behind endophyte-mediated disease resistance in strong creeping red fescue (Festuca rubra subsp. rubra) and identified the antifungal protein Efe-AfpA produced by Epichloë festucae as a key factor against.....»»
How ribosomes in our cells enable protein folding
Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature......»»
Scientists take atomic look at a protein complex that grants access to our DNA
To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions. However, in the cell nucleus, this access is limited b.....»»
Carlos Ghosn calls Nissan-Honda-Mitsubishi deal a ‘disguised takeover" by Honda
Fugitive former Nissan Chairman Carlos Ghosn says Nissan's plan to team with Honda and Mitsubishi smells like a ‘disguised takeover' by Honda but will be a difficult partnership to pull off successfully no matter how it shapes up......»»
This new AI modeler can turn pictures into 3D sculptures in seconds
Stability AI debuts AI model that turns flat images into 3D shapes.....»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Researchers elucidate mechanisms behind protein selectivity in adenosine receptor
In a new study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate th.....»»