How hydrophobicity shapes protein assemblies
Through a nuanced balance of electrical and hydrophobic forces, biological molecules self-assemble into the large functional structures that maintain life's vital functions. Understanding how proteins self-assemble requires knowledge of both forces......»»
A simple and robust experimental process for protein engineering
A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study by University of Michigan researchers......»»
"GPS nanoparticle" platform precisely delivers therapeutic payload to cancer cells
A newly developed "GPS nanoparticle" injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cel.....»»
New study discovers how altered protein folding drives multicellular evolution
Researchers have discovered a mechanism steering the evolution of multicellular life. They identify how altered protein folding drives multicellular evolution......»»
Pok Pok Montessori-inspired iOS app launches interactive ‘Shapes’ toy
A new toy has landed for the fantastic Montessori-inspired iOS app Pok Pok. “Shapes” helps kids with fine motor skills, problem-solving, imagination, confidence, and more. more….....»»
Often seen, never studied: First characterization of a key postsynaptic protein
A protein that appears in postsynaptic protein agglomerations has been found to be crucial to their formation. The Kobe University discovery identifies a new key player for synaptic function and sheds first light on its hitherto uncharacterized cellu.....»»
How new product development shapes firms and the economy
Understanding product life cycles plays an important role in the innovation arms race, helping to define firm growth and market competition......»»
Scientists use a new type of nanoparticle that can both deliver vaccines and act as an adjuvant
Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins. These vaccines often include other molecules called adjuvants, which help to boost the immune system's response to the protein......»»
Researchers use electrocatalysis for site-specific protein modification
Boston College researchers used a mild charge of electricity to precisely modify proteins, a new tool that can be used to develop novel biotherapeutics and protein-based research tools, the team reported recently in the journal Nature Chemistry......»»
Breakthrough in nanostructure technology for real-time color display
A technology that enables the real-time display of colors and shapes through changes in nanostructures has been developed by Professor Kang Hee Ku and her team in the School of Energy and Chemical Engineering at UNIST. The technology has the potentia.....»»
Newly discovered protein prevents DNA triplication
Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent. This means that, millions of times a day, a biochemical wonder takes place in the body: the copying of the DNA molecule. I.....»»
Research team develops protein-based microcapsule for point-of-care diagnostics
Aptamers, the nucleic acid-based biosensors with the ability to bind specific proteins or small molecules, offer a way to identify target molecules without the complexity of analytical apparatuses. While being increasingly used in diagnostic applicat.....»»
Scientists discover radiation from massive stars shapes planetary systems
How do planetary systems such as the solar system form? To find out, CNRS scientists taking part in an international research team studied a stellar nursery, the Orion Nebula, using the James Webb Space Telescope. By observing a protoplanetary disk n.....»»
How the SARS-CoV-2 virus acquires its spherical shape
For centuries, coronaviruses have triggered health crises and economic challenges, with SARS-CoV-2, the coronavirus that spreads COVID-19, being a recent example. One small protein in SARS-CoV-2, the membrane protein, or M protein, is the most abunda.....»»
Increasing soil salinity: New discovery may help make crops more resilient
Salination causes harvests to fail across the globe. Plants die, or their growth is stunted. Researchers of Wageningen University & Research (WUR) have discovered that a local regulator protein encourages root growth in saline soil, which allows the.....»»
Fluorescent protein outshines the competition when imaging cells
Delicate cellular structures and dynamic processes within cells that were hitherto unseen could be revealed by the next generation of a green fluorescent protein developed by chemists at RIKEN......»»
Researchers observe the structural heterogeneity of a lipid scramblase
Researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Nature Communications that TMEM16F, a transmembrane protein that facilitates the passive movement of phospholipids and ions across membranes, explores a larger.....»»
Unlocking the color code: The role of VvBBX44 and VvMYBA1 in regulating grape anthocyanin biosynthesis
Anthocyanins significantly influence grape quality and color, with transcription factors HY5 and MYBA1 playing pivotal roles in their biosynthesis. Recent findings show that VvBBX44, a B-box protein, inhibits anthocyanin production in grapes by suppr.....»»
Metal in glitter impairs aquatic plant growth, study shows
Glitter is used in a wide array of colors and shapes in apparel, footwear, cosmetics, makeup, handbags, festive decorations, arts and crafts, and jewelry, among many other applications. During the Carnival holidays, hundreds of thousands of Brazilian.....»»
Researchers reveal how cells regenerate protein factories at the endoplasmic reticulum
The synthesis of proteins in the cell is a key process of life. By this means, the genetic code of the genome is translated into the amino acid sequence of proteins. The process is complex—and has been studied in detail for decades......»»
Live imaging reveals key cell dynamics in 3D organ formation in Drosophila
Animal development requires successive changes in cell and tissue structures. To form complex 3D organs, cell shapes must adapt to support tissue morphogenesis. However, our understanding of how cellular structure changes are coupled with dynamic tis.....»»