How hydrophobicity shapes protein assemblies
Through a nuanced balance of electrical and hydrophobic forces, biological molecules self-assemble into the large functional structures that maintain life's vital functions. Understanding how proteins self-assemble requires knowledge of both forces......»»
Flat faces and difficulty breathing: How pet trends have harmed animal health—and what we can we do about it
Dogs come in all shapes and sizes. We've molded some of them to have large protruding eyes, sloping backs and shortened legs through selective breeding......»»
New small molecule helps scientists study regeneration
Regenerating damaged tissues or organs has been a dream of scientists for decades. Now, researchers at the FMI and Novartis Biomedical Research have discovered a new molecule that activates a protein involved in regeneration. The tool holds promise f.....»»
The best of WWDC -- the developer conference that shapes technology for the rest of us
Apple's annual Worldwide Developers Conference isn't as high profile as its iPhone launches. But, it has been the setting for moments that have radically changed the company — and all of our lives.Tim Cook announcing Apple Silicon at WWDC 2020The i.....»»
Researchers map protein network dynamics during cell division
An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the.....»»
Some plant-based steaks and cold cuts are lacking in protein, researchers find
Many plant-based meats have seemingly done the impossible by recreating animal products ranging from beef to seafood. But beyond just the taste and texture, how do these products compare to the real thing in nutritional value? A small-scale study pub.....»»
Key protein regulates immune response to viruses in mammal cells
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and.....»»
How a calcium-sensing protein multitasks
The calcium-sensing receptor is critical for maintaining healthy calcium levels, but CaSR is also well-known for its side hustles. The receptor is increasingly recognized for its ability to detect other ions and proteins and for its role in breast ca.....»»
A powerful technique for tracking a protein"s fleeting shape changes
Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate "movies" of changing protein structures and speeds of up to 50 frames per second......»»
New class of antimicrobials discovered in soil bacteria
Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species......»»
Illuminating the path to hearing recovery: Structural insights into a receptor protein"s role in auditory function
Researchers have worked to uncover the mysteries surrounding a specific receptor protein associated with hearing. Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republ.....»»
New time-resolved ultraviolet photodissociation mass spectrometry strategy for target protein stability analysis
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle structure dynamics is st.....»»
New study details how starving cells hijack protein transport stations
A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions......»»
Researchers develop method to extract useful proteins from beer-brewing leftovers
Researchers from Nanyang Technological University, Singapore (NTU Singapore), have created a method that extracts more than 80% of the available protein in grain leftovers from brewing beer, commonly known as brewers' spent grain......»»
"Fallout" star Ella Purnell shares BTS of stuntman flossing in power armor
"Fallout" star Ella Purnell appeared on "The Tonight Show" and shared a video of stuntman Adam Shippey flossing in Maximus' power armor. What good is wearing a seven foot suit of armor if you're not at least going to throw a few shapes in it?Th.....»»
"Kinds of Kindness" teaser sees Emma Stone throwing some serious shapes
A new teaser for Yorgos Lanthimos' "Kinds of Kindness" sees Emma Stone dancing like no-one is watching. There's a new teaser for Yorgos Lanthimos' hotly anticipated Kinds of Kindness, and this time it mainly features the director's Poor Things.....»»
A promising target for new RNA therapeutics now accessible
Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein mo.....»»
New protein imaging method supports the design of innovative new cancer drugs
Scientists have successfully used a new imaging technique to determine the structure and interactions of a protein complex that plays a significant part in the initiation and progression of cancer. They showed that it was possible to use a high-resol.....»»
Scientists report that buffer and pH strongly affect the phase separation of SARS-CoV-2 N protein
In a new paper published in Molecular Biology of the Cell, the Allain lab (IBC) reported that the phase separation of the SARS-CoV-2 N protein strongly depends on the chosen buffer and pH. For example, the protonation of a single histidine side chain.....»»
New method reveals secrets of protein interactions with potential for drug discovery
Scientists from the University of Oulu (Finland) and Texas A&M University (U.S.), have developed a new method to study how proteins interact with small ligand molecules, paving the way, for example, for faster and more efficient drug discovery......»»
New study paves the way for precision drugs to treat blood cancers
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent signaling and under.....»»