How hydrophobicity shapes protein assemblies
Through a nuanced balance of electrical and hydrophobic forces, biological molecules self-assemble into the large functional structures that maintain life's vital functions. Understanding how proteins self-assemble requires knowledge of both forces......»»
Genes spatially organize for efficient mRNA splicing, study shows
The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 times smaller than the width of a human hair, genes a.....»»
DeepMind adds a diffusion engine to latest protein-folding software
Major under-the-hood changes let AlphaFold handle protein-DNA complexes and more. Enlarge / Prediction of the structure of a coronavirus Spike protein from a virus that causes the common cold. (credit: Google DeepMind) M.....»»
MATE transporter facilitates bitter saponin transport from cytoplasm to vacuole
Domestic soybeans serve as an important source of healthy edible plant oil and high-quality plant protein in our food culture. In addition to the well-known components of oil (approximately 20%), protein (approximately 40%), and carbohydrates (approx.....»»
Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins
A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. Th.....»»
Synthetic chemistry approach yields new compounds with potential biomedical applications
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability to modulate protein-protein.....»»
How mantle movements shape Earth"s surface
The movement of tectonic plates shapes the rocky features of Earth's surface. Plates' convergence can form mountain ranges or ocean trenches, and their divergence can form oceanic ridges. But it's not just the plates themselves that influence Earth's.....»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
How the plant world shapes the climate cycle
In order to understand the Earth's resilience, researchers at ETH Zurich are modeling climate changes from times long past. And they show that plants are not simply victims of circumstances, but have helped to shape climate conditions on Earth......»»
Microgravity-grown crystals reveal new insights into protein structures
Biochemists have long been working around a blind spot when it comes to proteins. They know that hydrogen constitutes nearly half of the atoms in proteins, but how they contribute to protein function in these complex structures has been less clear. H.....»»
Researchers develop tiny droplets that harness laser light to detect disease markers
A team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has created tiny droplets that, when activated by laser light, can detect viral protein biomarkers indicating the presence of certain diseases......»»
Bacteria "nanowires" could help develop green electronics
Engineered protein filaments originally produced by bacteria have been modified by scientists to conduct electricity. In a study published recently in the journal Small, researchers revealed that protein nanowires—which were modified by adding a si.....»»
Study sheds light on the diversity of carnivore skull shapes and their function
In a study published in Nature Communications, a team of international researchers led by Gabriele Sansalone and Carmelo Fruciano has made a significant discovery about the diversity of skull shapes in carnivores......»»
The real reason so many laptops have moved to soldered RAM
Soldered RAM is becoming very common in laptops of all shapes and sizes -- but is that a good thing?.....»»
A new way to study and help prevent landslides
Landslides are one of the most destructive natural disasters on the planet, causing billions of dollars of damage and devastating loss of life every year. By introducing a new paradigm for studying landslide shapes and failure types, a global team of.....»»
Researchers decipher how an enzyme modifies the genetic material in the cell nucleus
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»
Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell
The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»
Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater
Scientists from Nanyang Technological University, Singapore (NTU Singapore) and Temasek Polytechnic have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a "single cell protein" cultivated from microbes in.....»»
Imaging technique shows new details of peptide structures
A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies—stacks of peptides that include amyloid beta, most notably associated with Alzheimer's disease......»»
AI designs active pharmaceutical ingredients quickly and easily based on protein structures
A new computer process developed by chemists at ETH Zurich makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process, detailed in Nature Communications, could re.....»»
Apple Vision Pro shipments reportedly cut as US demand for headset wanes
Ming-Chi Kuo says Apple has reduced its orders for Apple Vision Pro parts and assemblies, with the cut in shipments said to indicate lower demand for Apple's headset than previously thought.Apple Vision ProThe launch of the Apple Vision Pro in the Un.....»»