How does an intestinal microbe become a pathogen?
The bacterium Escherichia coli is found in the human intestine, and elsewhere. There it is harmless, but in certain conditions it can become a pathogen. It can cause bladder infections or even sepsis. A team of researchers led by RESIST professor Mar.....»»
Identifying intestinal microbiota bacteria that protect against antibiotic-resistant pathogens
A study by the "Microbiota, Infection and Inflammation" research group at the Foundation for the Promotion of Health and Biomedical Research of Valencia Region (Fisabio), an agency of the Conselleria de Sanitat Universal i Salut Pública, has identif.....»»
Spraying compound probiotics improves growth performance, modulates gut microbiota of suckling piglets
One factor that shapes the establishment of early neonatal intestinal microbiota is environmental microbial exposure, and probiotic application has been shown to promote health and growth of piglets, but inferences drawn from different studies are la.....»»
Significant alterations of intestinal symbiotic microbiota mediate changes in intestinal metabolism
As an effective method of preventing a wide range of bacterial diseases, vaccination plays a key role in aquaculture disease control, contributing to its environmental, social, and economic sustainability. In particular, vaccines based on inactivated.....»»
Study: Presence of E. coli is a poor indicator of fecal pollution
Escherichia coli is best known as a gastrointestinal pathogen in warm-blooded animals. For the last hundred years, its presence on beaches has been assumed to indicate fecal pollution, leading to beach closures. New research examines the genetic basi.....»»
Studies find that microbiome changes may be a signature for myalgic encephalomyelitis/chronic fatigue syndrome
Researchers have found differences in the gut microbiomes of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) compared to healthy controls. Findings from two studies, published in Cell Host & Microbe add to growing evidence th.....»»
Scientists Grew Mini Human Guts Inside Mice
These tiny organoids with working immune systems mimic the function of the GI tract and could be used to study intestinal diseases and drugs to treat them......»»
Evolutionary trade-offs: Balancing genetic disease risks and pathogen protection
Certain genes can exist in different, functionally divergent variants in the individuals of a species. If they lead to clear differences, for example in a phenotype or susceptibility to disease, this is known in biology as a polymorphism. Typical exa.....»»
How a sugar cane pathogen is gearing up a new era of antibiotic discovery
A potent plant toxin with a unique way of killing harmful bacteria has emerged as one of the strongest new antibiotic candidates in decades......»»
Researchers discover novel mechanism for MRSA virulence
Researchers at Mount Sinai, in collaboration with researchers at New York University, have published a study in Cell Host & Microbe that sheds light on the mechanisms behind the severity, or virulence, of methicillin-resistant Staphylococcus aureus (.....»»
Lethal pathogen causes widespread biological disruption for frogs, but responses differ by species
A new study by a Western Sydney University researcher has explored a lethal fungal pathogen causing widespread biological disruption for frogs, assessing how responses differ by species across the globe......»»
Sugar-based inhibitors that can disarm the pathogen Pseudomonas aeruginosa
The hospital pathogen Pseudomonas aeruginosa requires the sugar-binding proteins LecA and LecB to form biofilms as well as to attach to and penetrate host cells. These so-called lectins are therefore suitable targets for active substances to combat P.....»»
Legionella bononiensis: A new Legionella species has been identified
They call it Legionella bononiensis: it is the 64th species of Legionella identified worldwide, the second to be isolated in Italy since the discovery of the pathogen. It was discovered in 2019 in a hotel facility by researchers from the Laboratory o.....»»
Deciphering disease progression and cell processes with TIGER, in vivo and non-invasively
Could patients in the future simply ingest a diagnostic probiotic based on programmed ribonucleic acids to analyze their intestinal health from individual cells? Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the J.....»»
Investigating the intestinal transport of mercury ions with a gut-on-a-chip device
The transport of mercury ions across intestinal epithelial cells can be studied for toxicology assessments by using animal models and static cell cultures. However, the concepts do not reliably replicate conditions of the human gut microenvironment t.....»»
Scientists discover a new way of sharing genetic information in a common ocean microbe
From the tropics to the poles, from the sea surface to hundreds of feet below, the world's oceans are teeming with one of the tiniest of organisms: a type of bacteria called Prochlorococcus, which despite their minute size are collectively responsibl.....»»
Researchers reassemble plasmid to deliver genes across diverse environmental microbiomes
Microbiome engineering is at the forefront of improving human health and agricultural productivity. It aims to enhance ecosystem function by altering microbe composition. This can be accomplished through a "bottom-up" approach involving the introduct.....»»
Feeding apple waste to chickens may boost their health
An apple a day may keep the livestock veterinarian away. Juice, pulp and other waste from Empire apples, when injected into chicken eggs before hatching, show signs of boosting the animal's intestinal health, according to Cornell research......»»
Researchers investigate the role of sulfides in aerobic/anaerobic switching in bacteria
The bacteria in our intestinal tract play many essential roles in maintaining our health and metabolism. Keeping these organisms happy and striking a good balance among species is therefore very important to remaining healthy. Many of these bacteria.....»»
The future of replacement organs is (quite possibly) here: Robust human intestinal organoids created in a lab
Growing miniature organ-like tissues in the lab is already within our reach. Now, researchers from Japan have developed a new approach that enables intestinal mini-organs to be grown more easily and efficiently in the lab. This holds immense promise.....»»
Researchers discover a master regulator of plant immunity
The demonstration that a regulatory protein linked to stress responses in plants also serves as a master switch for anti-pathogen immunity could help breeders develop more pest-resistant and climate-resilient crops......»»