How cancer cells make lactic acid to survive
For the first time, researchers have shown how cancer cells reprogram themselves to produce lactic acid and to tolerate the acidic environment that exists around tumors. The finding could lead to a whole new direction for treating cancer......»»
Fireworks forecast if comet survives risky sun flypast
A comet is expected to risk having its tail clipped on Friday by flying perilously close to the sun, promising fireworks next month should it survive the fraught flypast......»»
Elucidating the mechanism of cell division during plant self-healing
When the stem of a plant is injured, the surrounding cells proliferate to repair and fuse the damaged tissue, eventually restoring function. This self-healing property is utilized in grafting techniques to propagate fruit and vegetable plants......»»
Another building block of life can handle Venus" sulfuric acid
Venus is often described as a hellscape. The surface temperature breaches the melting point of lead, and though its atmosphere is dominated by carbon dioxide, it contains enough sulfuric acid to satisfy the comparison with Hades......»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Building better bone grafts: Nanofibrous scaffolds to activate two main collagen receptors in bone cells
Each year, about 2.2 million bone-grafting procedures are performed worldwide, the gold standard of care being autografting, which uses the patient's own bone for tooth implantation and to repair and reconstruct parts of the mouth, face and skull......»»
Scientists develop method to control timing of synthetic DNA droplet division
Many cellular functions in the human body are controlled by biological droplets called liquid-liquid phase separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside living cells but are not enclosed by membranes like.....»»
Biofuel production: Rhodococcus strain N1-S transforms succinic acid production
As the global push for sustainable biofuels intensifies, lignocellulosic biomass has emerged as a prime candidate for biofuels and biochemicals owing to its abundance and renewability. This biomass, derived from plant materials, holds great promise a.....»»
Semimetal-induced covalency achieves high-efficiency electrocatalysis for platinum intermetallic compounds
Compared with other types of batteries, proton exchange membrane fuel cells have the advantages of high discharge power and no pollution, which is also an important carrier for hydrogen energy conversion and utilization. Platinum intermetallic compou.....»»
Ingredients used in chewing gum help tilapia survive cold climates
Two common ingredients in ordinary chewing gum—Arabic gum and lecithin—have been found to help improve the overall health of tilapia, helping these fish survive better even in cold climates. This discovery paves the way for raising tilapia for fo.....»»
New insights into hot carrier solar cells: Study explores hot electron tunneling and collection to enhance efficiency
Hot carrier solar cells, a concept introduced several decades ago, have long been seen as a potential breakthrough in solar energy technology. These cells could surpass the Shockley–Queisser efficiency limit, which is a theoretical maximum efficien.....»»
Mechanism behind autophagy trigger unveiled
An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy, a self-degradation process cells use to eliminate unneeded or damaged components. In recent years, autophagy has also been.....»»
Yeast chit-chat: How microorganisms communicate food shortages
To grow and survive, tiny organisms such as yeast must sometimes adapt their nutrient sources in response to changes in the environment. FMI researchers have now found that yeast cells communicate with each other to use less favorable nutrients if th.....»»
Climate change is a pollution problem, and countries have stopped similar threats before—think DDT and acid rain
Climate change can seem like an insurmountable challenge. However, if you look closely at its causes, you'll realize that history is filled with similar health and environmental threats that humanity has overcome......»»
Compact "gene scissors" enable effective genome editing, may offer future treatment of high cholesterol gene defect
CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissors" but is much smaller and thus easier to transport into cells......»»
Giant panda skin cells transformed into stem cells to help ensure their survival
A team of biologists in China has reprogrammed skin cells from giant pandas into induced pluripotent stem cells (iPSCs), opening the door to creating primordial germ cells that could serve as precursors to sperm and egg cells......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
Frostpunk 2 goes wider and more political but keeps the gritty, stressful joy
Sequel has yet again made losing your humanity to survive somehow… fun? Enlarge / Frostpunk 2 has you planning and building districts, rather than individual buildings or roads. You make plans, and a particularly icy god laughs.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»