How a key immune protein is regulated in the cell
Scientists at EPFL have determined how a protein that is critical in our first line of immune defense is regulated in the cell to prevent autoinflammatory diseases......»»
Researchers uncover key insights into cholesterol"s structure in cell membranes
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. Th.....»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
New progenitor cell type discovered, may aid in tissue repair and generation
A team of SAHMRI scientists has discovered a completely new type of cell that has the potential to enhance the future of tissue repair and generation......»»
New biosensor illuminates physiological signals in living animals
Eric Schreiter and Luke Lavis thought they had figured it out. In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Don"t overlook microorganisms" role in planet health, scientists warn
The tiniest and oldest creatures on—and in—Earth have a huge role in achieving a sustainable future for the planet, an international team of scientists, including faculty researchers from The Ohio State University, asserts in a new Cell article p.....»»
A $1 billion solar cell factory is coming to this U.S. state — and hundreds of new jobs are on the way
A $1 billion solar cell factory is coming to this U.S. state — and hundreds of new jobs are on the way.....»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
Scientists find new epigenetic switch, revealing how genes are regulated in early development
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early emb.....»»
Meet the Advocates and Researchers Revolutionizing Sickle Cell Care
These sickle cell researchers and advocates are driving change from labs to global stages, transforming lives in the process......»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»
Researchers Seek New Solutions to Ease Sickle Cell’s Extreme Pain
Sickle cell disease causes severe pain that’s hard to treat, but researchers are finding new ways to offer relief.....»»
A Global Initiative to Advance Sickle Cell Research Could Benefit Millions
Increased funding and new public health policies for sickle cell research are needed to ease the burden on low-income nations and improve patient care.....»»
People Living with Sickle Cell Disease Share Their Experiences
Life expectancy for people with sickle cell in the U.S. has increased to about 50 years, but some people with the disease still face stigma and other barriers in health care.....»»
New Hope for Treating People with Sickle Cell Disease
Improving sickle cell care by expanding treatment options, advancing new therapies and amplifying the voices of people with the disease.....»»
New Sickle Cell Treatments Highlight the Power of Patient Perspectives
Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine.....»»
Going Back to the Moon, Researching Chickadee Hybrids and Understanding Addiction
This month’s issue covers the reasons it’s so hard to go back to the moon, the science of empathy and new advances in treating sickle cell disease.....»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
An unexpected protein connection in maize growth and defense could enhance crop resilience
Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored......»»