How a calcium-sensing protein multitasks
The calcium-sensing receptor is critical for maintaining healthy calcium levels, but CaSR is also well-known for its side hustles. The receptor is increasingly recognized for its ability to detect other ions and proteins and for its role in breast ca.....»»
Expansion in situ genome sequencing innovation makes hidden DNA-protein interactions visible
Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The innovation allowed researchers to link nucleus abnormaliti.....»»
Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry
The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»
Targeting "undruggable" diseases: Researchers reveal new levels of detail in targeted protein degradation
Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and ne.....»»
Oxidative stress: How protein recycling protects against cell death
Researchers at LMU University Hospital have discovered a new molecular switch that protects against cell death......»»
Scientists discover how innate immunity envelops bacteria
The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now......»»
AI-driven approach challenges traditional views on protein structure
In a recently published article in Nature Communications,, a team offers an AI-driven approach to explore structural similarities and relationships across the protein universe. The team includes members from the University of Virginia—including Phi.....»»
Detailed images of key protein complexes provide new insights into bacterial photosynthesis
Researchers at the University of Liverpool and collaborators have arrived at a new understanding of bacterial photosynthesis. Using novel techniques, investigators have unveiled intricate detailed images of the key photosynthetic protein complexes of.....»»
Protein structure and design software gets the Chemistry Nobel
One academic and two people from DeepMind take home the Nobel. On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pion.....»»
Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level
Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»
Cellular agriculture research manages to culture pork fat tissue on rye protein scaffolds
National University of Singapore (NUS) food scientists have developed a simple and scalable method for culturing pork fat tissue using protein scaffolds made from secalin, a protein extracted from rye......»»
Scientists find plant-like behavior in human cells
A team of scientists from Monash University has solved the structure of a protein known as "LYCHOS," which can detect and regulate cell growth by sensing cholesterol levels in the body......»»
Ancient protein structure may have enabled early molecular evolution and diversification
In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab experiments that have revealed a previously unknown protein fold, which is completely absent in modern proteins......»»
Filament structure found to activate and regulate CRISPR-Cas "protein scissors"
CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, al.....»»
Protein involved in the early stages of age-related macular degeneration offers hope for prevention
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the United States. Despite existing treatments, the underlying causes of this disease and effective therapies remain elusive. Research published in the journal D.....»»
Researchers create orientation-independent magnetic field-sensing nanotube spin qubits
Purdue University researchers have developed patent-pending one-dimensional boron nitride nanotubes (BNNTs) containing spin qubits, or spin defects. The BNNTs are more sensitive in detecting off-axis magnetic fields at high resolution than traditiona.....»»
Researchers determine how a protein contributes to human immune defense against RNA viruses
An international research team led by Prof. Dr. Janosch Hennig from the University of Bayreuth has discovered how the TRIM25 protein contributes to defense against RNA viruses whose genetic material is contained as ribonucleic acid (RNA)......»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
DNA nanotechnology unravels complex protein interactions to inform cancer diagnostics
A team of researchers from NUS Institute for Health Innovation & Technology (iHealthtech), led by Associate Professor Shao Huilin and Associate Professor Brian Lim, has developed a first-of-its-kind technology to map out diverse protein interactions.....»»
Protein study reveals how the tiny shrew achieves a resting heart rate of 1,020 beats per minute
The shrew's resting heart rate can reach up to 17 beats per second, equivalent to about 1,020 beats per minute. In comparison, the average human resting heart rate is around 60 to 100 beats per minute, making the shrew's resting heart rate approximat.....»»
A new apparatus for analyzing partial coherence in integrated photonic networks
Anyone familiar with optics labs is familiar with the extremes of light coherence: laser beams are highly coherent, producing clear interference patterns used for precise applications like atomic manipulation or precise sensing. In contrast, light fr.....»»