Histone mutational landscape of human cancers
Researchers have completed a comprehensive analysis of cancer-associated histone mutations in the human genome, featuring both biochemical and cellular characterizations of these substrates. Their study reports that histone mutations that perturb nuc.....»»
Researchers suggest that mechanical pressure triggers a key event in HIV infection
It has been more than 40 years since the beginning of the HIV/AIDS epidemic and scientists still don't fully understand how HIV enters and replicates in human cells, which has hindered the development of treatments......»»
Genetic adaptations have impacted the blood compositions of two populations from Papua New Guinea, finds study
Papua New Guinea (PNG) has a wide range of environments, each presenting unique challenges to human survival. Highlanders and lowlanders of PNG are striking examples of populations facing distinct environmental stress. Whereas the highlanders encount.....»»
Women should be included in decisions on the protection of human rights in the climate crisis, say researchers
Eighty percent of climatic migrants are women and children. This figure means that a new international legal framework is required to protect human rights by adding gender-sensitive measures to policies and legislation. This is the claim made by Susa.....»»
Better reservoir management could aid food security and fisheries conservation in US
After nearly a century of people building dams on most of the world's major rivers, artificial reservoirs now represent an immense freshwater footprint across the landscape. Yet, these reservoirs are understudied and overlooked for their fisheries pr.....»»
Scientists" research on RNA editing illuminates possible lifesaving treatments for genetic diseases
A team at Montana State University published research this month that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs. The work reveals a new process in human cells that has potential for treating a wide variety of geneti.....»»
Cartilage healing discovery in animal models could lead to new human therapies
Researchers hope their discovery about the healing properties of fetal cartilage cells in mice will lay the groundwork for new treatments for human growth disorders and degenerative diseases......»»
Isotopic evidence reveals surprising dietary practices of ancient hunter-gatherers
It has long been thought that meat played an important role in the diet of hunter-gatherers before the Neolithic transition. However, due to the scarcity of well-preserved human remains from Paleolithic sites, little information exists about the diet.....»»
Prehistoric Irish monuments may have been pathways for the dead
Archaeologists have used advanced lidar technology to discover hundreds of monuments in the famous prehistoric landscape of Baltinglass, Ireland, revealing insights into the ritual activities of the farming communities that occupied the area......»»
Mammals on "sky islands" may be threatened by climate change, human development
A new study sheds light on how climate change and human development threaten mammal species living in isolated biodiversity hotspots known as "sky islands.".....»»
Human activities have an intense impact on Earth"s deep subsurface fluid flow
The impact of human activities—such as greenhouse gas emissions and deforestation—on Earth's surface have been well-studied. Now, hydrology researchers from the University of Arizona have investigated how humans impact Earth's deep subsurface, a.....»»
New quarantine scheme could reduce risk of rabies reintroduction in the EU following Russian invasion, study finds
Rabies is a major concern to both human and animal health, with rabies in dogs and cats widespread in Eastern Europe, and there are concerns the war in Ukraine could pose a greater risk of rabies being reintroduced to the European Union (EU). A four-.....»»
Researchers decipher how an enzyme modifies the genetic material in the cell nucleus
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»
Granting legal "personhood" to nature is a growing movement: Can it stem biodiversity loss?
Biodiversity is declining at rates unprecedented in human history. This suggests the ways we currently use to manage our natural environment are failing......»»
NASA astronauts arrive for Boeing"s first human spaceflight
The two NASA astronauts assigned to Boeing's first human spaceflight arrived at their launch site Thursday, just over a week before their scheduled liftoff......»»
A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»
Philippines" counter-terrorism strategy still stalled after 7 years since the "ISIS siege" on Marawi
Following the 2017 siege of Marawi, the Philippines' counter-terrorism efforts have faced an increasingly complex and unpredictable landscape. While authorities have claimed victory, one which garnered global media attention during the peak of ISIS r.....»»
Managing meandering waterways in a changing world
Just as water moves through a river, rivers themselves move across the landscape. They carve valleys and canyons, create floodplains and deltas, and transport sediment from the uplands to the ocean......»»
Advanced cell atlas opens new doors in biomedical research
Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about huma.....»»
Congo accuses Apple of using illegal conflict minerals in its supply chain
The Democratic Republic of Congo is accusing Apple of using illegally exploited minerals sourced in the eastern regions, involving violence, child labor and other human rights violations. This allegation disagrees with Apple’s published Conflic.....»»
Emperor penguins perish as ice melts to new lows: Study
Colonies of emperor penguin chicks were wiped out last year as global warming eroded their icy homes, a study published Thursday found, despite the birds' attempts to adapt to the shrinking landscape......»»