Glycerol phosphate serves as a terminator of glycan elongation in cancer malignancy
Dystroglycans on epithelial cell surfaces interact with the extracellular matrix via long sugar chains (called matriglycans), and they are responsible for cell adhesion. Abnormalities in the formation of matriglycans can impair cell adhesion and caus.....»»
Nanoparticle technology demonstrates selective destruction of leukemia cancer cells
A research team, affiliated with UNIST has developed nanoparticles that effectively treat acute myeloid leukemia (AML), offering the potential to reduce side effects while enhancing therapeutic efficacy by selectively targeting and eliminating leukem.....»»
Team develops promising new form of antibiotic that makes bacterial cells self-destruct
To address the global threat of antibiotic resistance, scientists are on the hunt for new ways to sneak past a bacterial cell's defense system. Taking what they learned from a previous study on cancer, researchers from the University of Toronto (U of.....»»
Molecular "cut and sew" process could accelerate drug design
A innovative molecular "cut and sew" process by University of Dundee scientists has allowed the design of a research tool that will accelerate drug design for diseases for which no other options exist, including cancer......»»
Single-molecule imaging reveals aberrant DNA-binding dynamics of cancer-linked chromatin remodelers
Biophysical chemists from the National University of Singapore (NUS) have uncovered a previously hidden landscape that governs the intracellular organization and dynamics of SWI/SNF chromatin remodelers, an important class of protein complexes that c.....»»
Plant fungus provides new drug target for colorectal cancer therapy
Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide......»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
Apple secretly tapped BYD for long-range EV battery tech, report says
Apple and BYD teamed up around 2017 to build a battery system using lithium iron phosphate cells, Bloomberg reported, signaling just how far the iPhone maker went in its efforts to produce a car......»»
Nanoparticle therapy offers new hope for prostate cancer patients
Prostate cancer is the second leading cause of cancer death among American men. A recent study, conducted by researchers from the University of Virginia, Mount Sinai, the University of Michigan, the University of Texas and others, has demonstrated th.....»»
The Kindle Colorsoft is a Kindle we’ve waited years for
Amazon revealed the Kindle Colorsoft Signature Edition, an e-reader that serves up a color panel inside a waterproof chassis, with wireless charging support......»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
Canopy structure regulates autumn phenology by mediating microclimate in temperate forests, finds study
Autumn phenology serves as a sensitive indicator of temperate forests' response to climate change and is a key factor influencing forest carbon sequestration. Understanding the mechanisms driving the spatiotemporal variations in autumn phenology is c.....»»
Highly-stabilized and selective inhibitor for cancer-causing enzyme developed
A team of researchers from the Hebrew University of Jerusalem, the Weizmann Institute of Science, and the University of Tokyo has made a significant breakthrough in the fight against cancer by developing a highly selective inhibitor for an enzyme cal.....»»
New bacteria-based therapy shows promise for fighting cancer
Even as cancer remains a leading cause of death globally, bacteria-based cancer therapy presents an exciting and innovative treatment option. Owing to their ability to penetrate the rigid stromal barrier, bacteria can naturally target solid tumors an.....»»
Quantum research unlocks PET scan potential in disease detection
New research in quantum entanglement could vastly improve disease detection, such as for cancer and Alzheimer's disease......»»
Why a diabetes drug fell short of anticancer hopes
Studies suggested it could treat cancer, but the clinical trials were a bust. Pamela Goodwin has received hundreds of emails from patients asking if they should take a cheap, read.....»»
High-resolution structural data shows how a supercomplex links mRNA translation and decay
Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena Conti and her team at the Max Planck Institute of Biochemistry in Martinsried near Munich have now been able to show that the.....»»
Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level
Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»
Alcohol Plays a Major Role in New Cancer Cases
A new report estimates that 40 percent of all cancer cases are associated with factors we can change—alcohol consumption being a prominent one......»»
Cancer, cardiovascular drugs tipped for Nobel as prize week opens
Cancer research or drugs treating cardiovascular illnesses could win a Nobel Prize on Monday when a week of laureate announcements kicks off, bringing a ray of optimism to a world beset by crises......»»
Ford eases driving for cancer patients
The Ford SupportBelt is designed to reduce painful seat belt pressure on women recovering from a mastectomy......»»