Glycans can regulate their own biosynthesis by modifying enzyme activity
Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of cells and.....»»
Antithrombin study proposes new mechanism of action for the plasma protein"s functional role
Antithrombin, a plasma protein, has been reported to control thrombin activity by directly binding to thrombin, as well as to have an anti-inflammatory effect. However, the actual molecular mechanism of the anti-inflammatory effect of antithrombin wa.....»»
How can you write data to DNA without changing the base sequence?
A new method lets anyone with a kit write data to DNA with just one enzyme. Zettabytes—that’s 1021 bytes—of data are currently generated every year. All of those cat videos.....»»
Glycans can regulate their own biosynthesis by modifying enzyme activity
Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of cells and.....»»
Unique multidomain enzymes from bacteria identified
Pharmaceutical scientists from the National University of Singapore (NUS) have identified and characterized a unique multidomain enzyme capable of catalyzing two distinct types of reactions, both vital for making drug molecules......»»
A good cyber leader prioritizes the greater good
In the war against malicious cyber activity, it’s time for security vendors to step in – and it’s not how you might think. CISA Director Jen Easterly put it right at this year’s Black Hat conference: “We got ourselves into this; we have to.....»»
Synthesis method improves catalytic activity by controlling the surface structure of metal particles
Fine-tuning the reactions that produce hydrogen (H2) for use as a clean fuel is an important endeavor to fight against climate change. Researchers at Tohoku University and the Tokyo University of Science have succeeded in improving the catalytic acti.....»»
Natural compound found in flowers blocks activity of an enzyme involved in multiple sclerosis and cancer
Scientists have identified a natural compound that halts the process involved in the progression of certain forms of cancer and demyelinating conditions—those that damage the sheath, known as myelin, that surrounds neurons—such as multiple sclero.....»»
Apple Vision Pro guest mode may soon be controlled via iPhone
Code discovered in iOS 18.2 indicates that Apple Vision Pro owners may get to control guest mode via iPhone through a Live Activity session.Apple Vision Pro guest mode could soon be controlled by iPhoneThe current process for setting up Apple Vision.....»»
Column: Industry may need to think about Musk-Trump relations
We don't know why Elon Musk has become Donald Trump's biggest supporter, but he could be looking to regulate the regulators......»»
New chemical treatment reduces number of plant pores that regulate water loss
Researchers from Nagoya University Institute of Transformative Biomolecules (WPI-ITbM) in Japan and their colleagues have identified and derivatized a chemical compound that effectively regulates the density of stomata in model plants. Stomata are cr.....»»
Climate change to alter seasonal outdoor activity patterns in US
It can be hard to connect a certain amount of average global warming with one's everyday experience, so researchers at MIT have devised a different approach to quantifying the direct impact of climate change......»»
Scientists uncover how transcription drives motion within the genome
A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene regulation and expression......»»
Satellite-derived data on artificial light at night indicate rapidly increasing industrial activities in the Arctic
More than 800,000 km2 of the Arctic were affected by human activity in 2013, according to an analysis of satellite-derived data on artificial light at night. On average, 85% of the light-polluted areas are due to industrial activities rather than urb.....»»
Island arcs study reveals ancient connections between ocean chemistry and volcanic rocks
Bringing a novel approach to a classic problem, researchers have revealed how changes in ocean chemistry over the past 2 billion years have left an imprint on volcanic rocks formed in island arcs. Island arcs, which arise from volcanic activity along.....»»
Leveraging skyscraper architecture: New design enhances porosity and structural stability for metal-organic frameworks
The Burj Khalifa, the tallest building in the world, employs advanced construction techniques designed to withstand wind, seismic activity, and its own massive weight. Among these techniques is the "Meta Column System," which plays a pivotal role by.....»»
Cellular senescence research identifies key enzyme to promote healthy aging
A team at Kumamoto University has made a discovery that could help promote healthy aging. As the world's population ages, Japan's aging population in particular is growing at an unprecedented rate, making it crucial to extend healthy lifespans rather.....»»
Discovery of key protein for biosynthesis of plant defense steroids could enhance pest control strategies
Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum......»»
DNA-binding C2H2 zinc finger proteins also regulate RNA processing, researchers discover
Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study significantly expands our understanding of these proteins' funct.....»»
Mechanism of cobalt–manganese catalysts deciphered
Conventional catalysts for hydrogen production via water electrolysis usually contain precious metals and are expensive. However, cheaper alternatives have been developed, for example cobalt–manganese catalysts. They have a high activity and are st.....»»
Highly-stabilized and selective inhibitor for cancer-causing enzyme developed
A team of researchers from the Hebrew University of Jerusalem, the Weizmann Institute of Science, and the University of Tokyo has made a significant breakthrough in the fight against cancer by developing a highly selective inhibitor for an enzyme cal.....»»