Getting protein factories to run—How deubiquitinating enzymes moonlight as Fubi proteases
The small protein ubiquitin is particularly famous for marking proteins for degradation but it has also been shown to regulate virtually all cellular processes. In parallel to the ubiquitin system various other ubiquitin-like modifiers have evolved,.....»»
Synthetic chemistry approach yields new compounds with potential biomedical applications
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability to modulate protein-protein.....»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Honda plants 85,000 trees outside factories in Ohio
The initiative will increase biodiversity in the region near three of Honda's operations and will help the automaker get closer to its carbon neutrality goal......»»
Clumps of an otherwise non-toxic molecule inhibit strep"s DNA-cleaving enzymes, researchers discover
An entirely new approach to inhibiting DNA-cleaving enzymes works through the aggregation of an otherwise non-toxic molecule. This Kobe University discovery may lead to a much-needed method for curbing Streptococcus growth......»»
Apple"s iPhone factory shift has left a ghost town behind in China
Foxconn is closing factories in China as iPhone production moves elsewhere, and impacts beyond industry have been made crystal clear in a new video.A Foxconn facility signApple has long operated its production in China, but in recent years it has bee.....»»
Microgravity-grown crystals reveal new insights into protein structures
Biochemists have long been working around a blind spot when it comes to proteins. They know that hydrogen constitutes nearly half of the atoms in proteins, but how they contribute to protein function in these complex structures has been less clear. H.....»»
Researchers develop tiny droplets that harness laser light to detect disease markers
A team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has created tiny droplets that, when activated by laser light, can detect viral protein biomarkers indicating the presence of certain diseases......»»
Bacteria "nanowires" could help develop green electronics
Engineered protein filaments originally produced by bacteria have been modified by scientists to conduct electricity. In a study published recently in the journal Small, researchers revealed that protein nanowires—which were modified by adding a si.....»»
Researchers decipher how an enzyme modifies the genetic material in the cell nucleus
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»
Honda to spend $11 billion on four EV factories in North America
The new facilities are in addition to the previously announced EV hub in Ohio. Enlarge / Honda is investing CAD$15 billion (US $11 billion) to expand EV manufacturing in North America with four sites in Ontario, Canada. (credit:.....»»
Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell
The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»
Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater
Scientists from Nanyang Technological University, Singapore (NTU Singapore) and Temasek Polytechnic have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a "single cell protein" cultivated from microbes in.....»»
10 best coming-of-age movies of all time, ranked
The best coming-of-age movies of all time are celebrated for their ability to capture the universal experience of adolescence, from Stand by Me to Moonlight......»»
AI designs active pharmaceutical ingredients quickly and easily based on protein structures
A new computer process developed by chemists at ETH Zurich makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process, detailed in Nature Communications, could re.....»»
A new method for enzymatic synthesis of potential RNA therapeutics
A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases, enzymes commonly used for the synthesis of DNA,.....»»
New small molecule helps scientists study regeneration
Regenerating damaged tissues or organs has been a dream of scientists for decades. Now, researchers at the FMI and Novartis Biomedical Research have discovered a new molecule that activates a protein involved in regeneration. The tool holds promise f.....»»
Researchers map protein network dynamics during cell division
An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the.....»»
Suppliers scramble to avoid low factory utilization amid rocky EV transition
The uneven ramp-up of electric vehicle production and flattening EV sales growth in North America have left suppliers scrambling to make sure they're not left with significantly underutilized factories, supplier executives said......»»
Some plant-based steaks and cold cuts are lacking in protein, researchers find
Many plant-based meats have seemingly done the impossible by recreating animal products ranging from beef to seafood. But beyond just the taste and texture, how do these products compare to the real thing in nutritional value? A small-scale study pub.....»»