Genetically engineered cell therapies with mRNA lipid nanoparticles for transferrable platelets
Platelet transfusions are essential in managing bleeding and hemostatic dysfunction, and can be expanded to be used as cell therapy for a variety of diseases. The efforts to create such cell therapies require that researchers modify donor platelets t.....»»
Tubular scaffolds boost stem cell-driven bone regeneration in skull defects
Scientists from Sun Yat-sen University's School of Biomedical Engineering have developed tubular scaffolds made from electrospun membranes, which significantly enhance bone regeneration in critical skull defects......»»
Battery EVs vs fuel-cell EVs: Could hydrogen power your next car?
While battery EVs have a huge lead, there are still plenty of proponents of hydrogen EVs, or fuel-cell EVs. Could FCEVs actually take over? Well, probably not......»»
Archaeologists discover an ancient Neanderthal lineage that remained isolated for over 50,000 years
A fossilized Neanderthal discovered in a cave system in the Rhône Valley, France, represents an ancient and previously undescribed lineage that diverged from other currently known Neanderthals around 100,000 years ago and remained genetically isolat.....»»
Researchers identify new tools for anti-Acinetobacter drug development and AMR preparedness
University of Liverpool researchers have engineered a library of strains that can be used to develop new antibacterial compounds to help address antimicrobial resistance (AMR) in Acinetobacter baumannii bacteria......»»
A roadmap for using viruses to enhance crop performance
Humans, livestock and companion animals benefit from virus-based vaccines and gene therapies, but crops do not. This paradox is highlighted by an international research group led by the Institute of Molecular and Cellular Biology of Plants (IBMCP) wi.....»»
Iron-doped carbon-based nanoparticles boost cancer treatment with enhanced precision and safety
Recently, a collaborative research team led by Prof. Wang Hui and Prof. Qian Junchao from Hefei Institutes of Physical Science of the Chinese Academy of Sciences designed a catalytically active, photoresponsive, Fe-doped carbon nanoparticle (FDCN) fo.....»»
Silver nanoparticles and a new sensing method can fight back against antibiotic-resistant biofilms
From safeguarding our food supply to preventing hospital infections, the battle against antibiotic-resistant bacteria is a growing challenge. Some bacteria can form biofilms, thick aggregates of millions of individual cells surrounded by protective m.....»»
Biomolecules inside living cells can now be seen with infrared light thanks to new method
To accelerate biotechnology innovations, such as the development of lifesaving drug therapies, scientists strive to develop faster, more quantitative and more widely available ways to observe biomolecules in living cells......»»
Researchers examine protein arrangement in cell membrane that triggers programmed cell death
How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from the fields of physics, chemistry and medicine at Heinrich Heine University Düsseldorf (HHU) have combined and further develo.....»»
Studying fungi"s "weak link" to fight global rise in deadly fungal infections
A group of scientists at the Department of Energy's Oak Ridge National Laboratory have conducted neutron scattering research to reveal key information about fungus cell membranes that could aid in developing new antifungal treatments......»»
Research team achieves high-resolution 2D imaging for graphene devices under high pressure
A research team led by Prof Zhang Zengming from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) has combined nitrogen-vacancy (NV) centers in diamond with a diamond anvil cell (DAC) to achieve non-inv.....»»
Glitch in protein synthesis could affect tumor growth
During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation machinery carouses along the string of nucleotides that m.....»»
How context-specific factors control gene activity
Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene regulation; essentially how and when genes are turned.....»»
Saturday Citations: Teen seals photobomb research site; cell phones are safe; serotonin and emotional resilience
If you're not susceptible to urban myths and misinformation, there's a new study from the World Health Organization that will ease your 2010s-era anxieties about cell phones. There were a lot of other developments this week, including the return of B.....»»
Jail put ‘violent’ inmate in man’s cell and he was killed within 45 minutes, suit says
Jail put ‘violent’ inmate in man’s cell and he was killed within 45 minutes, suit says.....»»
Elevating analysis of genomic data with advanced mathematical techniques
A novel approach to analyzing single-cell RNA sequencing (scRNA-seq) data has been unveiled by NUS researchers. This method promises to enhance both the precision and speed of data interpretation, potentially accelerating progress in numerous areas o.....»»
Hijacking the command center of the cell: Nuclear parasites in deep-sea mussels
Most animals live in intimate relationships with bacteria. Some of these bacteria live inside the cells of their hosts, but only very few are able to live inside cell organelles (structures inside the cell, like organs in the body). One group of bact.....»»
Decoding the language of cells with the power of proteomics
Hundreds of millions of years ago, single cells joined forces to become multicellular organisms. At the foundation of this multicellular world is the cell surface: the plasma membrane surrounding each cell, where individual units meet and communicate.....»»
Q&A: How single-cell and spatial proteomics reveal proteins" nuanced roles in health and disease
When Steve Carr, senior director of the Proteomics Platform at the Broad Institute of MIT and Harvard, began working in proteomics, the field was able to detect only the most abundant proteins in a given sample. In recent years, increasingly sensitiv.....»»
New mRNA and gene editing tools offer hope for dengue virus treatment
Dengue virus, a painful and sometimes fatal mosquito-borne infection well known in tropical countries, is surging rapidly across the planet. Now, 4 billion people live in places at risk for the disease, like the southeastern United States, which does.....»»