Genetically engineered cell therapies with mRNA lipid nanoparticles for transferrable platelets
Platelet transfusions are essential in managing bleeding and hemostatic dysfunction, and can be expanded to be used as cell therapy for a variety of diseases. The efforts to create such cell therapies require that researchers modify donor platelets t.....»»
Better than blood tests? Nanoparticle potential found for assessing kidneys
In a study published July 29 in Advanced Materials, University of Texas at Dallas researchers found that X-rays of the kidneys using gold nanoparticles as a contrast agent might be more accurate in detecting kidney disease than standard laboratory bl.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Don"t overlook microorganisms" role in planet health, scientists warn
The tiniest and oldest creatures on—and in—Earth have a huge role in achieving a sustainable future for the planet, an international team of scientists, including faculty researchers from The Ohio State University, asserts in a new Cell article p.....»»
A $1 billion solar cell factory is coming to this U.S. state — and hundreds of new jobs are on the way
A $1 billion solar cell factory is coming to this U.S. state — and hundreds of new jobs are on the way.....»»
Meet the Advocates and Researchers Revolutionizing Sickle Cell Care
These sickle cell researchers and advocates are driving change from labs to global stages, transforming lives in the process......»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»
Researchers Seek New Solutions to Ease Sickle Cell’s Extreme Pain
Sickle cell disease causes severe pain that’s hard to treat, but researchers are finding new ways to offer relief.....»»
A Global Initiative to Advance Sickle Cell Research Could Benefit Millions
Increased funding and new public health policies for sickle cell research are needed to ease the burden on low-income nations and improve patient care.....»»
People Living with Sickle Cell Disease Share Their Experiences
Life expectancy for people with sickle cell in the U.S. has increased to about 50 years, but some people with the disease still face stigma and other barriers in health care.....»»
New Hope for Treating People with Sickle Cell Disease
Improving sickle cell care by expanding treatment options, advancing new therapies and amplifying the voices of people with the disease.....»»
New Sickle Cell Treatments Highlight the Power of Patient Perspectives
Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine.....»»
Going Back to the Moon, Researching Chickadee Hybrids and Understanding Addiction
This month’s issue covers the reasons it’s so hard to go back to the moon, the science of empathy and new advances in treating sickle cell disease.....»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»
Optogenetic control reveals collective cell behavior
New research led by the Institute for Bioengineering of Catalonia (IBEC) has studied the migratory movement of groups of cells using light control. The results show that there is no leader cell that directs the collective movement, as previously thou.....»»
Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»
Modified nano-sized cell particles found to boost cancer immunotherapy, reduce side effects
Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that bo.....»»
Beyond displays: Liquid crystals in motion mimic biological systems
Liquid crystals are all around us, from cell phone screens and video game consoles to car dashboards and medical devices. Run an electric current through liquid crystal displays (LCDs) and they generate colors, thanks to the unique properties of thes.....»»
New method to break down forever chemicals uses nanoparticles and ultrasound
What do firefighting foam, non-stick cookware, water-repellent textiles and pesticides all have in common? They all contain per- and polyfluoroalkyl substances, or PFAS—human-made chemicals that don't break down naturally. It's no wonder, then, tha.....»»
Fluorescent nanomaterial could transform how we visualize fingerprints
Researchers created a fluorescent nanoparticle using a combination of materials (MCM-41, chitosan and dansylglycine) to examine latent fingerprints. These nanoparticles have special properties that make them adhere well to fingerprint residues, even.....»»