Genetic "hitchhikers" can be directed using CRISPR
In a new study, North Carolina State University researchers characterize a range of molecular tools to rewrite—not just edit—large chunks of an organism's DNA, based on CRISPR-Cas systems associated with selfish genetic "hitchhikers" called trans.....»»
Breaking boundaries: PAM-less genome editing in soybean
CRISPR-Cas9 has transformed crop genetic improvement, yet its reliance on specific protospacer adjacent motif (PAM), sequences limits editing scope and efficiency. In soybean, a critical source of protein and oil, these limitations hinder the develop.....»»
From wild relatives to super tomatoes: Unearthing new genetic potential
Tomato breeding has historically depended on a narrow genetic pool, leading to decreased diversity and loss of valuable traits. Traditional methods and biparental populations fall short in harnessing the full potential of wild relatives, posing chall.....»»
Cells use alternative splicing to regulate gene expression, research suggests
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»
How fruit flies use internal representations of head direction to support goal-directed navigation
Animal behavior is known to rely on transforming sensory information into motor commands, often influenced by an animal's internal needs. While in mammals and other large animals this process is supported by complex brain processes, simpler versions.....»»
Study finds RNA molecule controls butterfly wing coloration
A team of international researchers has uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. In a study published in the Proceedings of the National Academy of Sciences, the team, led by Luca L.....»»
Public perceptions on the use of gene tech for environmental problems
Addressing public concerns about the suitability and safety of new innovations is crucial to the responsible use of genetic technologies for environmental problems, according to a new report on New Zealanders' perceptions commissioned by BioHeritage.....»»
"Silent" mutations found to have repercussions beyond their own gene
Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide in a codon is switched. In non-synonymous muta.....»»
Population genetic insights into the conservation of common walnut (Juglans regia) in Central Asia
Understanding species distribution, differentiation and the factors affecting genetic diversity is important for sustainable conservation and effective management, as well as the rational utilization of species germplasm......»»
From antiquity to adaptation: Tracing the genetic journey of east Asian chestnut varieties
Uncovering the genetic saga of Castanea trees, a study maps their evolutionary journey and local climate adaptations. This research reveals the genetic markers and molecular mechanisms that have allowed these nut fruit trees to adapt and flourish acr.....»»
New genetic sensor for DNA methylation discovered
DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and is a major way that DNA is epigenetically marked. Epigenetic modifications can act as on–off switches to regulate gene expression and hel.....»»
Researchers achieve first CRISPR-based genome editing in Nile grass rats
A team of researchers at Michigan State University has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats......»»
Vernicia montana"s genome unearths new breeding horizons
A study has unveiled the genetic blueprint of Vernicia montana, a plant renowned for its high-value tung oil and ornamental beauty. The research decodes its chromosome-level genome, providing unparalleled insights into its evolution and setting the s.....»»
From genome to grocer"s aisle: Decoding the Chinese cherry for firmer fruits
A significant milestone in horticultural genomics has been reached with the successful decoding of the tetraploid Chinese cherry genome. A recent study provides essential insights into the genetic factors that influence fruit firmness, a critical tra.....»»
Roundworm study paves way for better RNA-based drugs to treat human disease
RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer. These therapeutics can target and silence di.....»»
Advances in bermudagrass research highlight genetic insights, potential for environmental resilience
A research team has reviewed recent studies to highlight the significant progress in understanding the growth and stress response mechanisms in bermudagrass, a widely distributed and valuable grass species. A recent review reveals the genetic diversi.....»»
Novel ratchet mechanism uses a geometrically symmetric gear driven by asymmetric surface wettability
The ratchet mechanism is a fascinating energy-conversion system that converts disorderly or random motion into orderly, directed movement through a process known as spontaneous rectification. It is a critical component of mechanical systems, typicall.....»»
Sea anemone study identifies potentially regenerative stem cells linked to conserved genes
The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the se.....»»
A visionary approach: How a team developed accessible maps for colorblind scientists
Imagine having to do your job, but not being able to visually process the data right in front of you. Nearly 8% of genetic males and 0.5% of genetic females have some form of Color Vision Deficiency (CVD), or the decreased ability to discern between.....»»
DNA study challenges thinking on ancestry of people in Japan
A genetic study led by researchers from RIKEN's Center for Integrative Medical Sciences has uncovered evidence that people in Japan descend from three ancestral groups......»»
Elongated tortoises exhibit minimal genetic variation, aiding conservation efforts
The genetic homogeneity of the endangered elongated tortoise aids the species' protection, as demonstrated in a study by Senckenberg researchers and an international team, published in the journal Salamandra......»»