Gamma-secretase "buckles up" to reach its destination
New research has uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease. In a first step, two dimeric subcomplexes are formed, which independently exit.....»»
First spatial map of malaria infection in the liver opens new possibilities for more effective treatments
For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upward of seven days, making it a bottleneck in the parasite's lifecycle. This bottle.....»»
Studying the journey, not the destination, provides new insight into songbird migrations
Migration is an adaptive phenomenon, typically triggered by a change of season, that is vital to ecosystem health. Animals may journey thousands of miles, in some cases, in search of food, better living conditions, or to find a mate. Conversely, huma.....»»
A hopper could explore more than 150 km of Triton"s surface in two years
Neptune's largest moon, Triton, is one of the most biologically interesting places in the solar system. Despite being hard to reach, it appears to have active volcanoes, a thin atmosphere, and even some organic molecules called tholins on its surface.....»»
Apple Store Workers in Maryland reach ‘historic’ union contract with Apple [U: Approved]
After becoming the first Apple Store in the country to unionize back in June 2022, the retail employees at the Towson Town Center location have reached a “historic” union contract with Apple this week, providing numerous benefits to the workers......»»
Scientists discover highest-energy gamma-ray line in the universe
A research group led by the Institute of High Energy Physics (IHEP) of the Chinese Academy of Sciences (CAS) report the discovery of a gamma-ray line up to 37 million electron-volts from an extremely bright gamma-ray burst, which represents the highe.....»»
The next SSDs may be over 80% faster
Micron just unveiled its next-gen PCIe 6.0 SSD which will reportedly reach speeds of over 26GB/s. That's a massive increase over PCIe 5.0, but there's a catch......»»
Sniff test for explosives detection extends its reach
Scientists have developed a way to detect tiny amounts of hard-to-detect explosives more than eight feet away, reducing the need to swipe clothing, luggage or other materials......»»
Senate passed child protection bills, but ‘not a priority for the House’ [U]
The Senate has passed two major child protection bills that could have a dramatic impact on how social media apps operate. Update: Congress went into recess before the KOSA Act could reach a vote in the House, and a Wired report suggests the House Re.....»»
Trap review: M. Night Shyamalan’s new thriller is deeply stupid
Josh Harnett is creepily entertaining in Trap, a new M. Night Shyamalan movie that buckles under the weight of too many contrivances......»»
Carbon credits "ineffective", says corporate climate watchdog
The world's top judge of corporate climate action on Tuesday described carbon credits as "ineffective" at addressing global warming and a risk for companies trying to reach net zero targets......»»
Researchers develop 3D printed model for targeted antibiotic therapy against follicular infections
Hair follicle infections are often difficult to treat because bacteria settle in the gap between hair and skin, where it is difficult for active substances to reach them......»»
Podcasting getting tougher as big names get most of the cash and audience
Podcasting is getting tougher for those who don’t already have a significant following, says a new report, as a few big names take most of the cash and get most of the audience. Recent data shows that the top 25 podcasts reach almost half of reg.....»»
Apple Store Workers in Maryland reach ‘historic’ union contract with Apple
After becoming the first Apple Store in the country to unionize back in June 2022, the retail employees at the Towson Town Center location have reached a “historic” union contract with Apple this week, providing numerous benefits to the workers......»»
Fermi Telescope finds new feature in brightest gamma-ray burst yet seen
In October 2022, astronomers were stunned by what was quickly dubbed the BOAT—the brightest-of-all-time gamma-ray burst (GRB). Now an international science team reports that data from NASA's Fermi Gamma-ray Space Telescope reveals a feature never s.....»»
UAW, Lear reach tentative agreement, ending strike that idled GM Wentzville plant
The UAW and Lear Corp. reached a tentative agreement at a Missouri seating factory late July 24, ending a strike that idled midsize pickup and full-size van production at General Motors' Wentzville, Mo., assembly plant......»»
Google’s Play Store wants to pivot from grab-and-go to an active destination
If multi-app shopping doesn't keep you there, maybe free Pixel gear will. Enlarge / I like the idea of clicking "Realistic," "MMORPG," and "Word" boxes, just to see what comes back. (credit: Google) Google Play is a lot.....»»
Telomere-to-telomere genome assembly research opens the door to new crop varieties
Completely new crop varieties which can better withstand drought, salinity and pests are within reach thanks to international genomics research published today in Nature Genetics......»»
AT&T failed to test disastrous update that kicked all devices off network
AT&T caused outage that blocked 92 million calls, 25,000 attempts to reach 911. Enlarge (credit: Getty Images | AaronP/Bauer-Griffin) A government investigation has revealed more detail on the impact and causes of a rece.....»»
Retaining flavor while removing caffeine—a chemist explains the chemistry behind decaf coffee
For many people, the aroma of freshly brewed coffee is the start of a great day. But caffeine can cause headaches and jitters in others. That's why many people reach for a decaffeinated cup instead......»»
iOS PlayStation Emulator ‘Gamma’ receives a series of new updates
Gamma debuted on the App Store back in May, thanks to a new App Store policy change that began to allow game emulators. Gamma is a PlayStation 1 emulator for iPhone and iPad, and it has recently received a number of updates, making the emulator a who.....»»