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Fluorescent visualization and evaluation of NPC1L1-mediated cholesterol absorption at the levels of endocytic vesicles

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease. The absorption of intestinal cholesterol is primarily.....»»

Category: topSource:  physorgMar 28th, 2023

First 3D visualization of an aluminum nanocomposite for the auto industry

Manufacturing cars with strong, lightweight aluminum alloys rather than steel could improve fuel efficiency and extend electric vehicle range, but the material's instability at high temperatures has held the alloys back from widespread adoption......»»

Category: topSource:  physorgRelated NewsAug 2nd, 2024

Sea level changes shaped early life on Earth, fossils show

A newly developed timeline of early animal fossils reveals a link between sea levels, changes in marine oxygen, and the appearance of the earliest ancestors of present-day animals......»»

Category: topSource:  physorgRelated NewsAug 1st, 2024

Amazon ends the month with a $799 MacBook Air deal, plus get up to $200 off upgraded specs

The sale encompasses the M2 and M3 MacBook Air range, with prices falling to Prime Day levels.Save $200 on Apple's MacBook Air.With back-to-school shopping kicking into high gear, the MacBook Air is a popular choice given it's budget-friendly price p.....»»

Category: appleSource:  appleinsiderRelated NewsJul 31st, 2024

Weight loss drugs like Ozempic can also help people stop smoking

Drugs containing semaglutide, like Ozempic and Wegovy, are intended to help people with diabetes lower their blood glucose levels while also reducing the risk of … The post Weight loss drugs like Ozempic can also help people stop smoking appear.....»»

Category: gadgetSource:  bgrRelated NewsJul 31st, 2024

Researchers discover high levels of non-coding RNAs in testes, suggesting new roles in sperm function and evolution

Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had been previously esti.....»»

Category: topSource:  physorgRelated NewsJul 30th, 2024

Children"s safer use of technology linked to improved feelings of well-being

New research by the UCD School of Medicine looking at the level of digital skills among children aged 10 and 11 found those with a safe and positive understanding of technology and smart devices enjoyed overall higher levels of contentment compared t.....»»

Category: topSource:  physorgRelated NewsJul 30th, 2024

Insights into strawberry senescence: Hormonal interplay key to extending shelf life of "Benihoppe" variety

A research team discovered that the rapid senescence of harvested strawberry "Benihoppe" results from increased perishability, softening, water loss, increased soluble sugars within 2 d, and changes in hormone levels. They found that ABA, JA, and eth.....»»

Category: topSource:  physorgRelated NewsJul 30th, 2024

New reconstruction shows low Artic sea ice cover in mid-20th century

An international research team presented a new reconstruction of past Arctic sea ice that revealed low levels of sea ice coverage in the 1940s......»»

Category: topSource:  physorgRelated NewsJul 29th, 2024

Massive appropriation of labor from the Global South enables high consumption in rich countries

The high levels of consumption enjoyed by wealthy countries in the Global North are only possible because of mass appropriation of labor from the population of the Global South. This is evidenced by research from the Institute of Environmental Scienc.....»»

Category: topSource:  physorgRelated NewsJul 29th, 2024

As California seeks to curb groundwater declines, farmers in one county fight back in court

With long-term declines in groundwater levels putting thousands of domestic wells at risk and causing the ground to sink in parts of the San Joaquin Valley, state regulators are moving forward with efforts to force local agencies to take stronger ste.....»»

Category: topSource:  physorgRelated NewsJul 29th, 2024

Unlocking carbon"s potential: CRISPR boosts lignocellulose absorption

Lignocellulosic biomass, such as paper mulberry, holds promise for sustainable material production due to its cost-effectiveness and renewability. However, optimizing lignin composition remains challenging due to its complex structure and varied comp.....»»

Category: topSource:  physorgRelated NewsJul 29th, 2024

Bronx study tracks exposure to air pollution through the day—data reveal demographic disparities in exposure levels

There are significant differences in how much people are exposed to air pollution, according to a new study co-authored by MIT scholars that takes daily mobility into account......»»

Category: topSource:  physorgRelated NewsJul 29th, 2024

The cost of cybersecurity burnout: Impact on performance and well-being

This article includes excerpts from recent reports we covered, providing statistics and insights into the levels of stress and burnout experienced by cybersecurity professionals. Most cybersecurity pros took time off due to mental health issues Hack.....»»

Category: securitySource:  netsecurityRelated NewsJul 29th, 2024

Skullcandy’s surprisingly good headphones are down to $65 from $200

The Skullcandy Crusher Evo wireless headphones, which offer amazing bass levels and a battery life of up to 40 hours, are on sale at 67% off from Amazon's Woot......»»

Category: topSource:  digitaltrendsRelated NewsJul 26th, 2024

Grindstone, Apple Arcade fan favorite, scores 100 new levels in update

Looking for a great time on Apple Arcade? One of the service’s games with a strong fan following, Grindstone, just scored a big update that adds 100 new levels. more….....»»

Category: topSource:  informationweekRelated NewsJul 25th, 2024

Air pollution falls after London vehicle curbs: Mayor

London's Mayor Sadiq Khan on Thursday claimed success for his expanded pollution toll zone for motor vehicles, pointing to a drop in levels of a harmful air pollutant since its controversial introduction......»»

Category: topSource:  theglobeandmailRelated NewsJul 25th, 2024

Spatially decoupling bromide-mediated process boosts propylene oxide electrosynthesis

A research team led by Prof. Zeng Jie and Geng Zhigang from the University of Science and Technology of China (USTC) of Chinese Academy of Sciences (CAS), utilized bromide as a reaction medium to spatially decouple the electrolysis process and propyl.....»»

Category: topSource:  physorgRelated NewsJul 24th, 2024

Study links nanoparticles to oxidative stress and neuron death

Researchers at the University of Kentucky have a better understanding of the regulation of extracellular vesicles by oxidative stress and how these vesicles spread oxidative stress and may damage neurons. Extracellular vesicles are nanoparticles rele.....»»

Category: topSource:  physorgRelated NewsJul 23rd, 2024

New car smell reaches toxic levels on hot days, researchers find

A study of volatile organic compounds (VOCs) emitted by new cars on hot summer days finds concerning levels of formaldehyde and other aldehydes......»»

Category: topSource:  physorgRelated NewsJul 23rd, 2024

Comprehensive evaluation identifies top finger lime varieties for commercial and ornamental use

A research team has conducted a comprehensive evaluation of nine finger lime varieties, identifying key differences in fruit peel color and suitability for commercial production. Xiangbinhong emerged as the best variety for commercial production, whi.....»»

Category: topSource:  physorgRelated NewsJul 22nd, 2024