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Fluorescent visualization and evaluation of NPC1L1-mediated cholesterol absorption at the levels of endocytic vesicles

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease. The absorption of intestinal cholesterol is primarily.....»»

Category: topSource:  physorgMar 28th, 2023

Chloroplast manipulation: A new strategy in pathogen warfare uncovered

A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»

Category: topSource:  physorgRelated NewsAug 28th, 2024

Cultured zooplankton provide new avenue to monitor and rid oceans of microplastic pollutants

Testing for levels of microplastic contamination in marine plankton aims to help develop new ways to assess and manage the rising global pollution problem, Flinders University experts say......»»

Category: topSource:  physorgRelated NewsAug 28th, 2024

Tattoo ink sold on Amazon has high levels of weird and rare bacteria

The recall announcement noted that the germs "present a health concern." Enlarge / BARCELONA, SPAIN - 2021/10/02: Spanish tattoo artist Oscar Garcia works on a man, during the Expo. Fira de Barcelona hosts the XXIV edition of the.....»»

Category: topSource:  arstechnicaRelated NewsAug 27th, 2024

Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation

Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»

Category: topSource:  physorgRelated NewsAug 26th, 2024

Socioeconomics found to shape children"s connection to nature more than where they live

The income and education levels of a child's environment determine their relationship to nature, not whether they live in a city or the countryside. This is the finding of a new study published in People and Nature and conducted by researchers at Lun.....»»

Category: topSource:  physorgRelated NewsAug 23rd, 2024

The 8 best OLED TVs for 2024

Experience the most accurate colors, contrast, and black levels you’ve ever seen on a TV with one of these amazing 2024 OLED TVs......»»

Category: topSource:  digitaltrendsRelated NewsAug 23rd, 2024

Pollution drives families to relocate—but only the rich can afford to live in healthier areas

Pollution levels factor in households' decision to relocate within the United States, but only richer households can afford areas with improved air quality, a new study finds......»»

Category: topSource:  pcmagRelated NewsAug 22nd, 2024

Fighting coastal erosion with electricity

New research from Northwestern University has systematically proven that a mild zap of electricity can strengthen a marine coastline for generations—greatly reducing the threat of erosion in the face of climate change and rising sea levels......»»

Category: topSource:  physorgRelated NewsAug 22nd, 2024

Honey bees may play key role in spreading viruses to wild bumble bees

Honey bees may play a role in increasing virus levels in wild bumble bees each spring, according to researchers at Penn State who analyzed seasonal trends of parasite and virus transmission in bees......»»

Category: topSource:  pcmagRelated NewsAug 21st, 2024

Some Chesapeake Bay goals won"t be reached by 2025, EPA evaluation finds

The EPA has released its latest evaluation of the Chesapeake Bay, and Virginia is only hitting some of its goals to meet by 2025......»»

Category: topSource:  physorgRelated NewsAug 21st, 2024

First visualization of valence electrons reveals fundamental nature of chemical bonding

The distribution of outermost shell electrons, known as valence electrons, of organic molecules was experimentally observed for the first time by a team led by Nagoya University in Japan. As the interactions between atoms are governed by the valence.....»»

Category: topSource:  physorgRelated NewsAug 21st, 2024

Unveiling the hottest period in a million years: The MIS 11c paradox

The hottest warm period in the past million years is believed to have occurred about 400,000 years ago. During this time, the Northern Hemisphere had less ice than today, and sea levels were about 10 meters higher. Surprisingly, solar radiation, a ke.....»»

Category: topSource:  physorgRelated NewsAug 21st, 2024

This year’s summer COVID wave is big; FDA may green-light COVID shots early

Wastewater SARS-CoV-2 levels suggest the summer surge is high and peaking right now. Enlarge (credit: Getty | Thomas Trutschel) With the country experiencing a relatively large summer wave of COVID-19, the Food and Drug.....»»

Category: topSource:  arstechnicaRelated NewsAug 20th, 2024

Green light for accurate vegetation research: Evaluation of global SIF datasets

A recent study has pinpointed the top-performing solar-induced chlorophyll fluorescence (SIF) products for precise global monitoring of photosynthesis and vegetation dynamics. By thoroughly evaluating eight widely-used SIF datasets, the research team.....»»

Category: topSource:  physorgRelated NewsAug 19th, 2024

Going slow is better for fast cycling: Study reveals unique replication fork behavior in pluripotent stem cells

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic replication stress. However, a recent report published in E.....»»

Category: topSource:  physorgRelated NewsAug 19th, 2024

Warming waters and nutrient overload: A dangerous combination threatening our rivers and lakes

Warming water temperatures and increased nutrient levels are putting freshwater ecosystems at serious risk, new research has revealed......»»

Category: topSource:  theglobeandmailRelated NewsAug 16th, 2024

Could manure and compost act like probiotics, reducing antibiotic resistance in urban soils?

Urban soils often contain chemical contaminants, such as heavy metals or trace amounts of antibiotics, along with higher levels of antibiotic-resistant bacteria. New research from the University of Maryland suggests that, in some cases, boosting urba.....»»

Category: topSource:  theglobeandmailRelated NewsAug 14th, 2024

Interactive map shows thresholds for coastal nuisance flooding

As sea levels rise around the world, communities in coastal areas are more frequently seeing the impact of routine high tide flooding. These incursions of sea water may weaken foundations and infrastructure, slow down traffic and curb business activi.....»»

Category: topSource:  physorgRelated NewsAug 14th, 2024

Municipal politicians claim to be ideological moderates. Is it true?

Municipal politicians often argue that local government is the part of the political world where things actually get done. Other levels of government might be plagued by partisan factionalism and ideological radicalism, they like to say, but municipa.....»»

Category: topSource:  physorgRelated NewsAug 14th, 2024

Trojan horse method gives malaria parasites a taste of their own medicine

More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive. Now, scientists from The Australian National University (ANU) say its role as.....»»

Category: topSource:  physorgRelated NewsAug 14th, 2024