Filament structure found to activate and regulate CRISPR-Cas "protein scissors"
CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, al.....»»
Exploring Huntington"s disease: Researchers discover that protein aggregates poke holes in the nuclear membrane
Researchers at Utrecht University in the Netherlands have identified a new way in which the toxic protein aggregates associated with Huntington's disease may damage nerve cells and cause them to die......»»
Research team releases a 76 m-per-pixel global color image dataset and map of Mars
Remote-sensing images of Mars contain rich information about its surface morphology, topography, and geological structure. These data are fundamental for scientific research and exploration missions of Mars. Prior to China's first Mars exploration mi.....»»
Tree mortality may lead to carbon tipping point in the Amazon by 2050s
The Amazon rainforest is home to a diverse cast of plants and animals. This vital, verdant landscape also plays a crucial role in managing the effects of climate change by storing significant amounts of carbon and helping regulate temperatures and ra.....»»
Newly discovered protein stops DNA damage
Researchers from Western University have discovered a protein that has the never-before-seen ability to stop DNA damage in its tracks. The finding could provide the foundation for developing everything from vaccines against cancer, to crops that can.....»»
Surprise finding in study of environmental bacteria could advance search for better antibiotics
In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial.....»»
Chromatin structure found to play a key role in canine social behavior evolution
A study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also plays a crucial role in gene regulation......»»
Harnessing compact RNA-guided endonucleases for enhanced genome editing
The review paper "CRISPR Beyond: Harnessing Compact RNA-Guided Endonucleases for Enhanced Genome Editing," authored by Feizuo Wang from National University of Singapore, presents a comprehensive examination of the advancements in CRISPR-Cas technolog.....»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
House call: A new study rethinks early Christian landmark
Since its discovery by modern researchers a century ago, an ancient structure known as the "Christian building" has become widely considered the cornerstone of early Christian architecture. Constructed around 232 C.E. in the ancient city of Dura-Euro.....»»
Nearly 25,000 Cadillac Lyriq EVs recalled for braking software glitch
Antilock braking system may activate at low speeds, increasing crash risk......»»
Study finds protein reduces toxicity of graphene oxide for drug delivery
A new study has discovered ways to reduce the toxicity of graphene oxide (GO), an ultra-thin sheet of nanomaterial derived from graphite, laying the groundwork to use it as a drug delivery system......»»
International team discovers key protein that helps cells maintain their identity
A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell. The discovery is the result of an international research collaboration, led by Professors Genevieve.....»»
Comparing Apple’s latest App Store changes in the EU to Google’s Play Store guidelines
Last week, Apple announced changes to its compliance strategy with the Digital Markets Act in the European Union. These changes apply to apps that link to a web page and include a new fee structure centered around the Initial Acquisition Fee and the.....»»
Researchers identify body"s "quality control" regulator for protein folding, could lead to targeted treatments
Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
Align or die: Revealing unknown mechanism essential for bacterial cell division
A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto "dying to align": Misaligned filaments "die" spontaneously to form a ring structure at the center of the dividing cell. The stud.....»»
Former Xbox head credits Apple watch with life-saving low heart rate alerts
Veteran tech executive Peter Moore credits his Apple Watch with an alert that ended up saving his life, resulting in the implantation of a pacemaker to regulate his heartbeat.Tech and sports exec Peter Moore is alive and well, thanks to his Apple Wat.....»»
The molecular shield: How tea plants combat drought through protein phosphorylation
Drought stress poses a significant challenge to agriculture, causing substantial yield losses in many crops. Tea plants, known for their rich flavonoid content which enhances both quality and health benefits, are particularly affected. Under drought.....»»
PhAI—an AI system that figures out the phase of x-rays that crystals have diffracted
A trio of chemists at the University of Copenhagen has developed an AI application that can be used to figure out the phase of x-rays that crystals have diffracted as part of efforts to predict the structure of small molecules......»»
Unlocking the potential of rapeseed: CRISPR edits for hybrid efficiency
Hybrid production in rapeseed faces several significant challenges, primarily due to the complexities and limitations of current male sterility systems. Traditional methods often involve intricate management processes and are highly sensitive to envi.....»»