FDA approves first CRISPR therapy—here’s how it works against sickle cell
The landmark treatment turns on another blood protein that prevents sickling. Enlarge / This digitally colorized scanning electron micrograph (SEM) revealed some of the comparative ultrastructural morphology between normal red b.....»»
Study sheds light on cancer cell "tug-of-war"
Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is a.....»»
How a "conductor" makes sense of chaos in early mouse embryos
Early embryonic development is tumultuous. It involves a rapid sequence of events, including cell division, differentiation, and lots of compartments moving around within each cell. Like an orchestra performance where each member of the band must sta.....»»
Microbiome studies help explore treatments for genetic disorders
A collaboration has led to the identification, in a bacterium of the intestine, of new CRISPR-Cas9 molecules that could have a clinical potential to treat genetic diseases such as retinitis pigmentosa, through sub-retinal injections. Anna Cereseto an.....»»
Nanoparticle researchers develop microfluidic platform for better delivery of gene therapy for lung disease
Drug delivery researchers at Oregon State University have developed a device with the potential to improve gene therapy for patients with inherited lung diseases such as cystic fibrosis......»»
Laboratory and natural strains of intestinal bacterium turn out to have similar mutational profiles
Understanding mutational processes in a cell offers clues to the evolution of a genome. Most actively, mutation processes are studied in human cancer cells, while other genomes are often neglected......»»
Rich molecular language guides tiny liquid droplet formation in cells
Peering into a biological cell reveals a bustling microscopic world. The workhorses within this realm are specialized structures called organelles that perform vital cellular functions. Curiously, some organelles defy accepted convention: Instead of.....»»
Usually $390, this HP 2-in-1 Chromebook is discounted to $270
Want a Chromebook that also works as a tablet? Check out the HP x360 Chromebook which is currently on sale at HP right now......»»
Researchers develop new AI tool for fast and precise tissue analysis to support drug discovery and diagnostics
A team of scientists from A*STAR's Genome Institute of Singapore (GIS) and Bioinformatics Institute (BII) has developed a new AI software tool called "BANKSY" that automatically recognizes the cell types present in a tissue, such as muscle cells, ner.....»»
Novel chemical tool for understanding membrane remodeling in the cell
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell......»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Hadeda ibises" "sixth sense" works best in wet soil: New research is a wake-up call for survival of wading birds
Hadeda ibises (Bostrychia hagedash) are one of the most familiar species of birds across sub-Saharan Africa. They are large, long-legged birds with long, thin beaks for probing invertebrates out of soil, and though they appear dull brown at a glance,.....»»
Researchers develop "founding document" on synthetic cell development
Cells are the fundamental units of life, forming the variety of all living things on Earth as individual cells and multicellular organisms. To better understand how cells perform the essential functions of life, scientists have begun developing synth.....»»
Bioreactor processes and cryotechnologies improve active ingredient tests using human cell cultures
Many new drug candidates end up failing because they cause serious side effects in clinical trials even though lab tests involving cell cultures have been successful. This is a common occurrence if the cells used come from animal tissue, for example......»»
Antimicrobial peptide from cows shows potential for treating hypervirulent bacteria
University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use to protect themselves from.....»»
Apple is deepening ties with China even as it boosts suppliers globally
Despite its well-publicized moves to cut its dependence on China as its main supplier, Apple has also been increasing the number of firms it works with for production with in the region.Tim Cook visits Luxshare factory in 2017. Source: AppleBy Januar.....»»
Toyota executives like fuel cell technology for zero-emission pickups
A hydrogen pickup would have bigger towing ranges and a fuel-like gasoline truck, Toyota executives say......»»
iOS 17.5 makes it less of a hassle to send your iPhone into Apple for repairs
Feature currently only works on iPhones, and not iPads, Macs, or Apple Watches. Enlarge (credit: Apple) If you've ever sent an iPhone in for repair, you might be familiar with the dance Apple asks you to do if your devic.....»»
Cell contraction drives the initial shaping of human embryos, study finds
Human embryo compaction, an essential step in the first days of an embryo's development, is driven by the contractility of its cells. This is the finding of a team of scientists from CNRS, Institut Curie, Inserm, AP-HP and the Collège de France. Pub.....»»
Toyota establishes North American hydrogen business headquarters in Los Angeles
The H2HQ facility will do R&D, commercialization and sales for hydrogen fuel cell products......»»