Examining mRNA transcription difficulties
The corona pandemic has ensured that the term "mRNA" is now also known to a large public beyond laboratories and lecture halls. However, the molecule is much more than an important component of a successful vaccine against the SARS-CoV-2 virus. "mRNA.....»»
Researchers capture never-before-seen view of gene transcription
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one.....»»
New mRNA technology turns cells into long-lasting drug factories
A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body,.....»»
US prepares for bird flu pandemic with $176M Moderna vaccine deal
Phase 3 trial is expected to begin next year. Enlarge (credit: Getty | Justin Sullivan) The US government will pay Moderna $176 million to develop an mRNA vaccine against a pandemic influenza—an award given as the high.....»»
Scientists are testing mRNA vaccines to protect cows and people against bird flu
The bird flu outbreak in U.S. dairy cows is prompting development of new, next-generation mRNA vaccines—akin to COVID-19 shots—that are being tested in both animals and people......»»
Researchers uncover protein SRSF1"s uncommon ability to bind and unfold RNA G-quadruplexes
RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department of Chemistry Professor Jun Zhang, Ph.D., and his te.....»»
As bird flu spreads in cows, US close to funding Moderna’s mRNA H5 vaccine
If trials are successful, US government likely to buy doses for vaccine stockpile. Enlarge (credit: Digicom Photo/Science Photo Library via Getty) The US government is nearing an agreement to bankroll a late-stage trial.....»»
Creating HR success: Key factors in training assessors for enhanced performance ratings
New research published in Industrial and Organizational Psychology from University of Alabama at Birmingham Collat School of Business faculty is examining how organizations can improve their training programs by customizing frame-of-reference trainin.....»»
Victim-blaming, manipulation, and denial: How terrorists use language to justify violence
Victim-blaming, denial and reversal are among the tactics used by terrorists to justify their violent actions and influence audience perceptions of harm and agency, according to a new Charles Darwin University (CDU) study examining the language of so.....»»
Lipid nanoparticle-mRNA regimen reverses inflammation and aids recovery from diabetic wounds in mice
Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown t.....»»
Hawaii study shows almost 75% of Maui wildfire survey participants have respiratory issues
A University of Hawaii study examining the health effects of last year's deadly wildfires on Maui found that up to 74% of participants may have difficulty breathing and otherwise have poor respiratory health, and almost half showed signs of compromis.....»»
iOS 18 will bring AI-powered audio transcription and summary features, per report
Apple has dabbled in audio transcription in the past with mixed success. One shining example lately has been Apple Podcasts transcripts; more pessimistically, voicemail transcripts are still subpar. But according to a new report, the upcoming iOS 18.....»»
Apple set to deliver AI assistant for transcribing, summarizing meetings and lectures
Apple later this year hopes to make real-time audio transcription and summarization available system-wide on many of its devices, as the iPhone maker looks to harness the power of AI in delivering efficiency boosts to several of its core applications.....»»
Genes spatially organize for efficient mRNA splicing, study shows
The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 times smaller than the width of a human hair, genes a.....»»
Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic mo.....»»
In Tesla Autopilot probe, U.S. prosecutors focus on securities, wire fraud
U.S. prosecutors are examining whether Tesla committed securities or wire fraud by misleading investors and consumers about its electric vehicles’ self-driving capabilities, three people familiar with the matter told Reuters. .....»»
Z-Library Confusion as ‘Official’ Social Media Announces Crackdown in China
Last month Z-Library reported that users in China were experiencing difficulties accessing the site, with new domains being blocked very quickly. The site's official WeChat and Bilibili social media accounts seemed unaffected until a surprise announc.....»»
Educational research should pinpoint anti-Black aggressions to build better policy, scholar writes
Educational research has long lumped all people of color together when examining microaggressions perpetrated against them. A University of Kansas scholar has published an article that argues educational research should instead study anti-Black aggre.....»»
Decoding development: mRNA"s role in embryo formation
A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights into how pluripotent cells a.....»»
Developing a tech platform for fast, robust series production of nanoparticles
Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are neede.....»»
Understanding cellular transcription responses to oxygen deprivation
A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»