Everything You Need to Know About Getting Your Genome Sequenced
DNA sequencing can assess your risk of developing certain diseases. It could even help provide medicines personalized to your genes one day. Governments want you to get involved......»»
How bats evolved to avoid cancer
A new paper titled "Long-read sequencing reveals rapid evolution of immunity and cancer-related genes in bats" in Genome Biology and Evolution shows that rapid evolution in bats may account for the animals' extraordinary ability to both host and surv.....»»
Notorious fungus Aspergillus fumigatus completely scrambles its genome after just one bout of sex
Researchers at Wageningen University & Research (WUR) have found that Aspergillus fumigatus produces more meiotic crossovers than any other organism. This means that the fungus can establish its complex resistance mechanism after just one cycle of se.....»»
A NICER approach to genome editing
The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended DNA mutations that ma.....»»
Researchers make genome prime editors smaller and more efficient for therapeutic applications
Prime editing technologies allow scientists to precisely edit the genome in a variety of ways and could one day be used to treat genetic diseases. Now researchers at the Broad Institute of MIT and Harvard have used cutting-edge continuous laboratory.....»»
Researchers determine how type II restriction endonuclease Sau3AI cleaves DNA
Sau3AI is a type II restriction enzyme widely used for genetic manipulation, such as genome library construction. Sau3AI consists of two domains, the N-terminal domain (Sau3AI-N) and the C-terminal domain (Sau3AI-C). How these two domains work togeth.....»»
Study provides evidence for hidden diversity within Hydnoraceae
Researchers from the Wuhan Botanical Garden of the Chinese Academy of Sciences (CAS) have conducted a phylogenetic analysis of Hydnora plants in the family Hydnoraceae through plastid genome sequencing, assembly and annotation after extensive data qu.....»»
The first telomere-to-telomere haplotype-resolved reference genome of triploid banana
Banana is one of the most important crops of the world. The demand for cultivated bananas continues to grow; however, their production is greatly affected by a complex of biotic and abiotic stresses. For instance, banana yields are severely threatene.....»»
New genetic analysis of Ötzi the Iceman yields some surprising findings
Ötzi’s ancestors were early Anatolian farmers, not Steppe Herders as previously believed. Enlarge / Study reveals that compared to other contemporary Europeans, Ötzi’s genome had an unusually high proportion of genes in com.....»»
Surprise! Ötzi the Iceman was bald and had darker skin than presumed
Ötzi’s ancestors were early Anatolian farmers, not Steppe Herders as previously believed. Enlarge / Study reveals that compared to other contemporary Europeans, Ötzi’s genome had an unusually high proportion of genes in com.....»»
The "weird" male Y chromosome has finally been fully sequenced. Can we now understand how it works, how it evolved?
The Y chromosome is a never-ending source of fascination (particularly to men) because it bears genes that determine maleness and make sperm. It's also small and seriously weird; it carries few genes and is full of junk DNA that makes it horrendous t.....»»
New gene-editing technique offers path to precision therapies
PNP editing is emerging as a versatile and programmable tool for site-specific DNA manipulations. An innovative genome-editing technique could enhance the delivery, specificity and targeting of gene-modifying tools for treatments......»»
Scientists reveal how proteins drive growth of multiple cancer types
Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone. Understanding how proteins operate in cancer cells raises the prospect of new therapi.....»»
High-precision genome sequencing of buckwheat breeds hope for future harvests
A research group led by Kyoto University's Graduate School of Agriculture has deciphered buckwheat's high-precision chromosomal-level genome sequence, a key step toward unraveling the evolution of the buckwheat genome and the origins of the cultivate.....»»
The "unknome": A database of human genes we know almost nothing about
Researchers from the United Kingdom hope that a new, publicly available database they have created will shrink, not grow, over time. That's because it is a compendium of the thousands of understudied proteins encoded by genes in the human genome, who.....»»
Size matters: Genome size dynamics driven by copy number variation in a green alga
A new study challenges the conventional wisdom surrounding genome stability within closely related organisms and sheds new light on the mechanisms underlying extensive genome size variation......»»
Your Genes May Influence What You Like to Eat
New research identifies genome areas linked to dietary patterns and our taste for things such as tea, tobacco and grapes.....»»
Genome data rewrite the story of oat domestication in China
Oat is among the top ten cereal crop species in terms of global production. It can adapt to different climates, and farmers can grow it successfully even in harsh environments where other crops such as rice and corn fail. However, not all oat plants.....»»
Genome analysis of 46,000-year-old roundworm from Siberian permafrost reveals novel species
Some organisms, such as tardigrades, rotifers, and nematodes, can survive harsh conditions by entering a dormant state known as "cryptobiosis.".....»»
Generation of a human haploid neural stem cell line for genome-wide genetic screening
Haploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific screens......»»
Modifying shelf-life of melons via gene editing
The gaseous plant hormone ethylene has been long known to promote fruit ripening and plays a certain role in shelf-life. In a study published in Frontiers in Genome Editing, researchers performed gene editing using the Clustered Regularly Interspaced.....»»