Epigenetic treatments: New allies for chemotherapies?
Though chemotherapies are effective in some patients, tumour cells may acquire tolerance to these treatments. In other words, cells adapt to chemotherapy so they can survive. A new study delivers promising results on epigenetic mechanisms that regula.....»»
Microbial allies may help turn tables on tar spot fungus in corn
Agricultural Research Service (ARS) scientists are leaving no stone—or rather, leaf—unturned in their search for new ways to counter the fungus that causes tar spot, a yield-robbing disease of field corn in the midwestern United States......»»
DNA methylation: The hidden mechanism enabling plants to adapt in a warmer world
As global warming continues to redefine ecosystems, plants are increasingly tasked with swift adaptation to ensure their survival. One primary mechanism facilitating such rapid adaptation is epigenetic memory, specifically DNA methylation......»»
Dangerous "Superbugs" Are on the Rise. What Can Stop Them?
Traditional antibiotics drive bacteria toward drug resistance, so scientists are looking to viruses, CRISPR, designer molecules and protein swords for better superbug treatments.....»»
New method to predict the risk of adverse drug events
Studying signaling within cells can predict the risk of adverse drug reactions of novel obesity and type II diabetes treatments before they reach the patient, according to a new study from Karolinska Institutet published in Nature Communications......»»
Epigenetic regulator MOF drives mitochondrial metabolism, new study shows
The intricate control of cellular metabolism relies on the coordinated and harmonious interplay between the nucleus and mitochondria. On the one hand, mitochondria are the hub for the production of essential metabolites, which aside from being requir.....»»
Timing plant evolution with a fast-ticking epigenetic clock
Recent discoveries in the field of epigenetics, the study of inheritance of traits that occur without changing the DNA sequence, have shown that chronological age in mammals correlates with epigenetic changes that accumulate during the lifetime of an.....»»
Facilitating a new nucleic acid detection platform
DNA phosphorothioate (PT)-modification, with a non-bridging oxygen in the phosphodiester backbone substituted by sulfur, is an epigenetic marker in prokaryotes and is involved in the bacterial defense system, anti-oxidative stress, and gene regulatio.....»»
Elk hoof disease likely causes systemic changes
Elk treponeme-associated hoof disease, previously thought to be limited to deformations in elks' hooves, appears to create molecular changes throughout the animal's system, according to epigenetic research from Washington State University......»»
Tiny bubbles could reveal immune cell secrets and improve treatments
Macrophages are cells vital to the immune system and could possibly inform cell-based therapies for a variety of medical conditions. However, realizing the full potential of macrophage therapies relies on being able to see what these cellular allies.....»»
New nanotech weapon takes aim at hard-to-treat breast cancer
Breast cancer in its various forms affects more than 250,000 Americans a year. One particularly aggressive and hard-to-treat type is triple-negative breast cancer (TNBC), which lacks specific receptors targeted by existing treatments. The rapid growt.....»»
Converting plant wastes into antimicrobial agents that could prevent pathogenic infections
Nebraska researchers are converting plant wastes into antimicrobial agents that could help prevent pathogenic infections and death while significantly lowering the cost of antimicrobial treatments and being a boon to the bioeconomy......»»
"American Horror Story: Delicate" trailer revels in the horror of pregnancy
The "American Horror Story: Delicate" trailer shows Anna (Emma Roberts) enduring horror of fertility treatments and pregnancy. The official trailer for American Horror Story: Delicate Part 1 is here, highlighting the unique horror of fertility.....»»
New bacteria discovery could lead to better treatments for people with cystic fibrosis
New research led by Queen's University Belfast has made a breakthrough in the field of microbiology, which could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis......»»
Biochemists focus on degrading key cancer-driving protein as a potential approach to stop cancer growth
Case Western Reserve University biochemical researchers have identified a new function of a key protein that leads to cancer—a finding they believe could lead to more effective treatments for a range of cancers and other diseases......»»
Cybersecurity experts say the west has failed to learn lessons from Ukraine
US and its allies struggle to copy Kyiv’s collaborative efforts. Enlarge / Viktor Zhora from Ukraine’s information protection service, says cyber has become a major component of hybrid warfare. (credit: Dragonflypd.com/Black.....»»
New gene-editing technique offers path to precision therapies
PNP editing is emerging as a versatile and programmable tool for site-specific DNA manipulations. An innovative genome-editing technique could enhance the delivery, specificity and targeting of gene-modifying tools for treatments......»»
Hard-of-hearing music fans prefer a different sound
Millions of people around the world experience some form of hearing loss, resulting in negative impacts to their health and quality of life. Treatments exist in the form of hearing aids and cochlear implants, but these assistive devices cannot replac.....»»
Who is Batman’s best sidekick? All the Dynamic Duos, ranked
Throughout the decades, Batman's had multiple allies by his side like Robin, Catwoman, and Red Hood. But which one of them is the absolute best?.....»»
Discovery of chikungunya virus"s "invisibility shield" may lead to vaccines or treatments
Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell—perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, c.....»»
Researchers develop versatile and low-cost technology for targeted long-read RNA sequencing
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children's Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules......»»