Enantioselective synthesis of indole derivatives
Indoles, and structures derived from them, are a component of many natural substances, such as the amino acid tryptophan. A new catalytic reaction produces cyclopenta[ b ] indoles—frameworks made of three rings that are joined at the edges—very s.....»»
A new reaction to enhance aromatic ketone use in chemical synthesis
Aromatic ketones have long been valuable intermediates in chemical synthesis, particularly in cross-coupling reactions where different chemical entities are combined to form new compounds. For instance, a process called deacylative cross-coupling rem.....»»
Mechanistic insights on SSZ-13 zeolite in catalytic dimethyl ether carbonylation
Dimethyl ether (DME) carbonylation to methyl acetate (MA) is one of the crucial steps in an indirect synthesis route of ethanol from syngas. SSZ-13 zeolite, with a typical topology of CHA, characterized by its 8-membered ring (8-MR) channels, has sho.....»»
New twist on synthesis technique promises sustainable manufacturing
James Tour's lab at Rice University has developed a new method known as flash-within-flash Joule heating (FWF) that could transform the synthesis of high-quality solid-state materials, offering a cleaner, faster and more sustainable manufacturing pro.....»»
Musk’s new Grok upgrade allows X users to create largely uncensored AI images
With Grok's new AI image generator, X users put Musk's "freedom of speech" to the test. Enlarge / An AI-generated image of Donald Trump and catgirls created with Grok, which uses the Flux image synthesis model. (credit: BEAST / X.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
Precise stirring conditions key to optimizing nanostructure synthesis
Stirring allows for homogenization and efficient gas exchange—this fact has been known for decades. Controlling the stirring rate during the nanocluster synthesis is pivotal in achieving nanostructures with well-defined sizes, structures, optical p.....»»
Research team achieves faster and more efficient synthesis of high-density RNA microarrays
An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used.....»»
Green synthesis of copper oxide nanoparticles from mangifera indica: A solution for agricultural disease management
A research team has successfully synthesized green copper oxide nanoparticles (CuO.NPs) from Mangifera indica (M. indica) leaf extract. The CuO.NPs showed potent activity against gram-positive and negative bacteria, as well as fungicidal effects on p.....»»
Breakthrough in Z-alkene synthesis: Scientists develop efficient and sustainable method
Z-alkenes are organic compounds with a double bond between two carbon atoms and two substituents attached to the carbon atoms on the same side of the double bond. They are ubiquitous structural components of organic compounds in chemistry and biology.....»»
New opportunities for organic synthesis under superheated flow conditions
Research programs from the Center for Integrated Technology and Organic Synthesis of the University of Liège (Belgium), demonstrate the many opportunities offered by micro/mesofluidic technologies to explore new reaction spaces......»»
Shining light on similar crystals reveals photoreactions can differ
A rose by any other name is a rose, but what of a crystal? Osaka Metropolitan University-led researchers have found that single crystals of four anthracene derivatives with different substituents react differently when irradiated with light, perhaps.....»»
We made a cat drink a beer with Runway’s AI video generator, and it sprouted hands
Gen-3 Alpha produces wild and whimsical results. Here's what it cooked up for us. Enlarge In June, Runway debuted a new text-to-video synthesis model called Gen-3 Alpha. It converts written descriptions called "prompts".....»»
Research team overcomes heteroatom constraints via cobalt catalysis
Professor Fu Yao and Associate Professor Lu Xi from the University of Science and Technology of China (USTC) have conducted a cobalt-hydride-catalyzed enantioselective hydroalkylation, enabling the efficient construction of chiral tertiary carbon cen.....»»
Synthesis of a new compound with excellent intrinsic magnetic properties using smaller amounts of rare earth elements
The National Institute for Materials Science has successfully synthesized a new SmFe-based magnetic compound, SmFe8.8N1.1, which possesses superior intrinsic magnetic properties when compared to those of NdFeB compound used in neodymium magnets. The.....»»
New technique streamlines synthesis of heavy element compounds
Molecular compounds with heavy elements, like americium, curium and others can now be synthesized in a streamlined and efficient way thanks to a new technique developed by Lawrence Livermore National Laboratory (LLNL) researchers......»»
Discovery of a tRNA modification enzyme that also acts on nucleosides
The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»
A comprehensive derivative synthesis method for development of new antimicrobial drugs
Efforts to combat the increasing threat of drug-resistant bacteria are being assisted by a new approach for streamlining the search for antimicrobial drug candidates, pioneered by researchers at Hokkaido University, led by Assistant Professor Kazuki.....»»
A better way to make RNA drugs: Enzymatic synthesis method expands capabilities while eliminating toxic byproducts
While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis. RNA therapies offer many advantages over tra.....»»
Unlocking the potential of anti-perovskites through a convenient one-step synthesis route
Although perovskites have attracted a lot of attention lately, anti-perovskites hold just as much potential as functional materials. Bearing a similar crystal structure to perovskites but with an inverted electrical configuration, anti-perovskites ex.....»»
Photoenzymatic synthesis achieves efficient oxidation of fatty acids
A research team designed and built a photoenzymatic cascade by combining photochemical water oxidation/O2 reduction with P450 peroxygenase catalysis to achieve efficient visible-light-driven oxidation of a range of fatty acids (C12-C20), leading to p.....»»