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Elucidating the biosynthetic mechanism for protoberberine alkaloids from Coptis chinensis

Protoberberine alkaloids are a group of tetracyclic isoquinoline compounds known for their well-established antimicrobial and anti-inflammatory properties. Although protoberberine alkaloids are broadly found in various plant families such as Ranuncul.....»»

Category: topSource:  physorgJan 16th, 2024

How network segmentation can strengthen visibility in OT networks

What role does the firewall play in the protection of operational technology (OT) networks and systems? Many would say that it’s the defensive mechanism to protect that environment from IT and the outside world. For the operators responsible fo.....»»

Category: securitySource:  netsecurityRelated NewsAug 8th, 2024

Researchers demonstrate mechanism that may have stabilized the first RNA molecules

The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team at ORIGINS, a Munich-based Cluster of Excellence, has demonstrated a mechanism that could have.....»»

Category: topSource:  physorgRelated NewsAug 2nd, 2024

Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs

Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»

Category: topSource:  physorgRelated NewsAug 2nd, 2024

When it comes to DNA replication, humans and baker"s yeast are more alike than different, scientists discover

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Scienc.....»»

Category: topSource:  pcmagRelated NewsAug 1st, 2024

Best OnePlus Open screen protectors to buy in 2024

Keep your OnePlus Open display safe and protected with these screen protectors. The post Best OnePlus Open screen protectors to buy in 2024 appeared first on Phandroid. The OnePlus Open is a foldable smartphone with a book-style mechanism......»»

Category: asiaSource:  phandroidRelated NewsJul 30th, 2024

Ice 0: Researchers discover a new mechanism for ice formation

Ice is far more complicated than most of us realize, with over 20 different varieties known to science, forming under various combinations of pressure and temperature. The kind we use to chill our drinks is known as ice I, and it's one of the few for.....»»

Category: topSource:  physorgRelated NewsJul 26th, 2024

Discovery of Piezo1"s new signaling mechanism may aid search for better pain and itch treatments

The human body's sense of touch is so important it can be found throughout the body, not just on the skin. Two tiny sensors of touch, Piezo1 and Piezo2, signal the lightest pressures and can be found monitoring the circulatory system, telling the bod.....»»

Category: topSource:  physorgRelated NewsJul 22nd, 2024

Researchers zero in on the underlying mechanism that causes alloys to crack when exposed to hydrogen-rich environments

When deciding what material to use for infrastructure projects, metals are often selected for their durability. However, if placed in a hydrogen-rich environment, like water, metals can become brittle and fail. Since the mid-19th century, this phenom.....»»

Category: topSource:  theglobeandmailRelated NewsJul 20th, 2024

Blue Origin shows off landing mechanism for New Glenn rocket

Blue Origin is aiming to land the first stage of its new rocket in late September, the New Glenn......»»

Category: topSource:  digitaltrendsRelated NewsJul 19th, 2024

Scientists uncover the molecular mechanism behind pineapple peel coloration

Pineapple peel coloration, especially the red hue, significantly enhances its commercial and aesthetic value. However, the genetic mechanisms driving this trait are not well understood, complicating breeding efforts for red-skinned varieties......»»

Category: topSource:  physorgRelated NewsJul 18th, 2024

Scientists develop dual-functional, high-efficiency antimicrobial nanozyme

A research team led by Prof. Gao Lizeng from the Institute of Biophysics of the Chinese Academy of Sciences proposed a bactericidal mechanism based on nanozymes that simulate antimicrobial peptides (AMPs) and antimicrobial enzymes (AMEs) according to.....»»

Category: topSource:  theglobeandmailRelated NewsJul 17th, 2024

E. coli variant may cause antimicrobial resistance in dogs, humans

Researchers studying antimicrobial-resistant E. coli—the leading cause of human death due to antimicrobial resistance worldwide—have identified a mechanism in dogs that may render multiple antibiotic classes ineffective......»»

Category: topSource:  physorgRelated NewsJul 16th, 2024

Nano-confinement may be key to improving hydrogen production

Researchers at Lawrence Livermore National Laboratory (LLNL) have discovered a new mechanism that can boost the efficiency of hydrogen production through water splitting......»»

Category: topSource:  physorgRelated NewsJul 15th, 2024

New Antikythera mechanism analysis challenges century-old assumption

Physicists drew on statistical techniques used to analyze gravitational waves. Enlarge / Fragment of the Antikythera mechanism, circa 205 BC, housed in the collection of the National Archaeological Museum, Athens. (credit: Fine A.....»»

Category: topSource:  arstechnicaRelated NewsJul 10th, 2024

Team discovers a new defense mechanism in bacteria

When confronted with an antibiotic, toxic substance, or other source of considerable stress, bacteria are able to activate a defense mechanism using cell-to-cell communication to "warn" unaffected bacteria, which can then anticipate, shield themselve.....»»

Category: topSource:  physorgRelated NewsJul 10th, 2024

Pear-derived discovery: A genetic mechanism to fortify crops against drought

A recent study has shed light on a critical genetic mechanism that boosts plants' ability to withstand drought. The research uncovers the role of the transcription factor PbERF3, native to wild pears, which works in concert with the protein PbHsfC1a.....»»

Category: topSource:  physorgRelated NewsJul 5th, 2024

Scientists uncover conserved mechanism of pericentric heterochromatin initiation in vertebrates

A study published in Nature on July 4 by Prof. Zhu Bing from the Institute of Biophysics of the Chinese Academy of Sciences has shed light on the conserved mechanism responsible for the initiation of pericentric heterochromatin in vertebrates......»»

Category: topSource:  physorgRelated NewsJul 5th, 2024

New theory reveals fracture mechanism in soft materials

A new theory has finally deciphered the physical mechanisms of fracture in soft materials. This discovery could soon lead to new, defect-free materials that are more resistant and durable as well as environmentally friendly. The article "Elastic inst.....»»

Category: topSource:  physorgRelated NewsJul 4th, 2024

Simulations demonstrate potential mechanisms of intermediate-mass black hole formation in globular clusters

Joint research led by Michiko Fujii of the University of Tokyo demonstrates a possible formation mechanism of intermediate-mass black holes in globular clusters, star clusters that could contain tens of thousands or even millions of tightly packed st.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

Scientists elucidate substrate recognition and proton coupling mechanism of transporter protein VMAT2

Vesicular monoamine transporter 2 (VMAT2) is the only transporter protein in the central nervous system that mediates the storage of monoamine neurotransmitters. It plays a critical role in mediating nerve impulse transmission and neuroprotection......»»

Category: topSource:  physorgRelated NewsMay 28th, 2024