Efficiently smuggling drugs into cells
A new, patented method called Progressive Mechanoporation makes it possible to mechanically disrupt the membranes of cells for a short time period and let drugs or genes inside cells. In this way, researchers can test new therapies more easily than b.....»»
Giant panda skin cells transformed into stem cells to help ensure their survival
A team of biologists in China has reprogrammed skin cells from giant pandas into induced pluripotent stem cells (iPSCs), opening the door to creating primordial germ cells that could serve as precursors to sperm and egg cells......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
Analysis of heterostructures for spintronics shows how two desired quantum-physical effects reinforce each other
Spintronics uses the spins of electrons to perform logic operations or store information. Ideally, spintronic devices could operate faster and more energy-efficiently than conventional semiconductor devices. However, it is still difficult to create a.....»»
Obesity-Drug Pioneers Win Prestigious Lasker Award for Medical Science
Three scientists are honored for developing a class of blockbuster weight-loss drugs. Is a Nobel prize on the way?.....»»
First-of-its kind tool allows scientists to manipulate cells without touching them
When studying the spread of cancer or the behavior of a virus like the one that causes COVID-19, the irony is that working with these harmful pathogens requires gentleness. Especially in the case of COVID, the particles do not survive well when makin.....»»
Visible-light-antenna ligand enhances samarium-catalyzed reactions
Samarium (Sm), a rare earth metal, is important to organic chemists because of the ability of its divalent compounds to efficiently perform single-electron transfer reductions......»»
Redwood Materials signs deal to recycle BMW’s EV batteries in the US
The automaker will use recycled materials from Redwood in its American-made EVs. Enlarge / BMW is moving to cylindrical cells for its sixth-generation EV powertrain, which debuts in the Neue Klasse. And now it has a recycling par.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
Computational tool can pinpoint causal relationships from complex biological data
Researchers have developed a tool that provides new insights into cause-and-effect relationships between cells and how these change over time......»»
Do bacteria age?
Any organism that lives, grows and reproduces must also age. People often think of aging in the physical sense—gray hair, slowed movements and wrinkles—but aging fundamentally occurs on a molecular level, inside of cells......»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»
Study sheds light on trade-off between noise and power in nanoscale heat engines
Thanks to nanoscale devices as small as human cells, researchers can create groundbreaking material properties, leading to smaller, faster, and more energy-efficient electronics. However, to fully unlock the potential of nanotechnology, addressing no.....»»
Optogenetic control reveals collective cell behavior
New research led by the Institute for Bioengineering of Catalonia (IBEC) has studied the migratory movement of groups of cells using light control. The results show that there is no leader cell that directs the collective movement, as previously thou.....»»
Researchers develop new method for delivering RNA and drugs into cells
Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases......»»
Trimetallic-based nanocarriers method shows promise for visualized idiopathic pulmonary fibrosis therapy
A research group from Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS) developed a novel method for idiopathic pulmonary fibrosis (IPF) therapy by transplanting mesenchymal stem cells (MSCs), w.....»»
Modified nano-sized cell particles found to boost cancer immunotherapy, reduce side effects
Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that bo.....»»