Drug is promising against pancreatic and breast cancers
The drug is effective at treating pancreatic cancer and prolonging survival in mice, according to a new study. A second study shows the drug is also effective against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast canc.....»»
New chemical method advances toward targeted RNA medicine
Targeted drugs aim to pinpoint the exact location in the body where diseased tissue is located and where the medicine is required. The manifold benefits of administering a targeted drug include heightened efficacy, as the drug is meticulously designe.....»»
Advances in nanoscale carrier-based approaches to enhance efficacy of podophyllotoxin
Podophyllotoxin (PPT), an aryltetralin-type lignan isolated from Podophyllum species, exhibits a wide range of biologic and pharmacologic activities, and mainly serves as an antiviral agent or antitumor drug in clinical applications......»»
Drug-resistant fungus is on the rise worldwide, says molecular biologist
The Candida auris fungus is spreading across the globe at an "alarming" speed. This species of fungus, which can cause fatal infections in risk groups and was first discovered only 10 years ago, can now be found all over the world. In nearly all case.....»»
Crystal language empowers AI to design novel materials with desired properties
Over the past decade, generative deep learning models have been applied successfully to the design of novel drug molecules, organic synthesis routes, and functional molecules tailored for electronic/optoelectronic devices. This is largely enabled by.....»»
Glassy shell of microscopic algae inspires tiny ultrasound detectors for medical imaging
A multidisciplinary team of researchers from Skoltech has discovered the resonance frequencies of diatom frustules. These intricately structured silicon dioxide shells of single-celled microalgae provide a promising model for nature-inspired electron.....»»
Adapting cybersecurity for the quantum computing era
Researchers are exploring promising quantum computing applications across various domains, from cryptography and optimization problems to drug discovery and artificial intelligence. The race to harness the power of quantum bits has sparked a wave of.....»»
A revolution in laptop RAM is upon us
A new, very promising RAM standard just got approved by JEDEC. What does that mean for the future of laptops?.....»»
Catalyst makes drugs inside the body to minimize side effects
A highly active catalyst capable of synthesizing drug molecules within the body has been developed by RIKEN chemists. In mice, an anticancer drug assembled near tumors using the injected catalyst suppressed tumor growth......»»
Spinning up control: Propeller shape helps direct nanoparticles, researchers say
Self-propelled nanoparticles could potentially advance drug delivery and lab-on-a-chip systems—but they are prone to go rogue with random, directionless movements. Now, an international team of researchers has developed an approach to rein in the s.....»»
Bimetallic alloy nanocatalyst boosts efficient ammonia production with potential for carbon-free energy
Ammonia (NH3) is regarded as a promising carbon-free energy carrier, but its energy-intensive production process still challenges global scientists. A research team led by City University of Hong Kong (CityU) recently engineered a bimetallic alloy as.....»»
Novel insights into antibody aggregation expected to open up new avenues for research and therapeutic applications
Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising candidates for future drug development. However, their light chains—par.....»»
When research study materials don"t speak their participants" language, data can get lost in translation
Imagine your mother has cancer. You just heard about a promising new experimental treatment and want to enroll her in the study. However, your mother immigrated to the U.S. as an adult and speaks limited English. When you reach out to the research te.....»»
New leader of GM"s Cruise acknowledges "all-time low" amid safety review
General Motors’ Cruise autonomous vehicle unit has hit an “all time low,” said its new leader, while promising to restore trust with regulators and the public after the company pulled all of its vehicles from U.S. roads......»»
Engineering customizable bio-adhesives for personalized medical repair
Traditional medical adhesives used in surgical applications often have limited bio-absorbability, high toxicity and a lack of customizability, leading to suboptimal surgical outcomes. Recent advances in synthetic biology offer a promising alternative.....»»
New approach to drug discovery: Developing pain medication with fewer side effects
People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery......»»
A deep-learning framework for drug–drug interactions and drug–target interactions prediction
Exploring the biomedical interactions for chemical compounds and protein targets is crucial for drug discovery. Determining these drug–drug interactions (DDI) and drug–target interactions (DTI) not only reveals the potential synergistic effects o.....»»
Examining advances in additive manufacturing of promising heterostructures and their biomedical applications
To the authors' knowledge, there have been no review papers that summarize the biomedical applications of heterostructures prepared by additive manufacturing. This paper aims to highlight the research progress in additive manufacturing of promising h.....»»
Nanomaterial with "light switch" kills Gram-negative or Gram-positive bacteria
Health care-associated infections are a common problem in suppurating wound care, as is the rise in multi-drug resistant bacteria. In order to effectively and selectively combat bacterial infections, a team of researchers has developed a bactericidal.....»»
Clean energy innovation or illusion? JETP climate funds
They were billed as an ingenious new way of helping developing countries ditch planet-polluting coal, promising an injection of billions from wealthy governments looking for new ways to tackle carbon emissions......»»
Breakthroughs in nanosized contrast agents and drug carriers through self-folding molecules
Self-folding polymers containing gadolinium forming nanosized complexes could be the key to enhanced magnetic resonance imaging and next-generation drug delivery, as demonstrated by scientists at Tokyo Tech. Thanks to their small size, low toxicity,.....»»