Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Enzyme study sheds light on the molecular mechanism behind "sleepiness"
Recent research has observed that chemical modifications called phosphorylation of proteins in brain neurons dynamically regulate sleep and wakefulness. But the protein kinases that suppress sleep and the dephosphorylation enzymes that control sleep.....»»
Multimodal machine learning model increases accuracy of catalyst screening
Identifying optimal catalyst materials for specific reactions is crucial to advance energy storage technologies and sustainable chemical processes. To screen catalysts, scientists must understand systems' adsorption energy, something that machine lea.....»»
Nanoscale bumps and grooves trigger big changes in cell behavior
The surfaces that cells come into contact with can influence how the cells grow, function, and communicate—shaping metabolism and even cellular health. Now, engineering researchers at the University of California San Diego have developed a platform.....»»
Infrared detectors made from quantum dots—a keener eye for the invisible
What do motion detectors, self-driving cars, chemical analyzers and satellites have in common? They all contain detectors for infrared (IR) light. At their core and besides readout electronics, such detectors usually consist of a crystalline semicond.....»»
Physicists take a step closer to controlling single-molecule chemical reactions
Controlling matter at the atomic level has taken a major step forward, thanks to nanotechnology research by an international team of scientists led by physicists at the University of Bath......»»
Stable perovskite catalyst achieves selective oxidation of light alkanes
Light alkanes are relatively simple molecules made entirely of carbon and hydrogen, arranged in linear or branching structures. Their oxidized counterparts, which include alcohols, epoxides, ketones, and aldehydes, are ubiquitous in the chemical indu.....»»
Novel organoid mimics all three key cell types of pancreas to offer a view of early fetal development
Researchers from the Organoid group (previously Clevers group) at the Hubrecht Institute have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development. The researchers were able to recreate a com.....»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
Seeing is believing: Leveraging defining morphological features for accurate selection of brain organoids
By combining morphological and single-cell level gene expression analyses, a team of researchers led by Professor Jun Takahashi in the Department of Clinical Application at Kyoto University has established a new non-destructive system to select high-.....»»
Cyclone Fengal toll rises to 20 in South Asia
The death toll from Cyclone Fengal's fierce push through Sri Lanka and southern India reached 20 on Monday as downpours and flooding followed the storm's wake after its winds calmed......»»
Minerals in hot springs performed a key chemical reaction for early life on Earth, new study confirms
One of the biggest scientific mysteries is where life on Earth started......»»
Watch Yellowstone season 5, episode 12: release date, time, channel, and plot
After last week's shocking death, things are becoming more dangerous for the Dutton family. Find out how and when to watch Yellowstone season 5, episode 12......»»
Novel quantum computing algorithm enhances single-cell analysis
A new quantum algorithm developed by University of Georgia statisticians addresses one of the most complex challenges in single-cell analysis, signaling significant impact in both the fields of computational biology and quantum computing......»»
Scientists reveal structural link for initiation of protein synthesis in bacteria
Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has been a visual mys.....»»
Chemical replacement of TNT explosive more harmful to plants, study shows
The increased use of a chemical compound to replace TNT in explosive devices has a damaging and long lasting effect on plants, new research has shown......»»
Man suffers chemical burn that lasted months after squeezing limes
The toxin is in more foods than you might think, including carrots, parsley, limes, and lemons. If Margaritaville were a real place, it should definitely keep a few dermatologists.....»»
Nanopesticide delivery system made with neem seed extract improves pesticide effectiveness
Pesticides can be made more effective and environmentally friendly by improving how they stick to plant surfaces, thanks to new research led by Dr. Mustafa Akbulut, professor of chemical engineering at Texas A&M University......»»
Cell model identifies important factor in neural development
The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the under.....»»
FCC approves Starlink plan for cellular phone service, with some limits
Starlink can provide cell service but FCC defers action on waiver of power limits. Starlink yesterday obtained federal approval to provide service to cell phones, with some limits.....»»
Shells, teeth and bones of "weird and wonderful organisms" provide historical environmental clues
An international study shows how chemical fingerprints left by "underappreciated" aquatic organisms could help scientists monitor global environmental change......»»